FR2408601A1 - Procede d'acylation d'une aniline substituee par une lactone en l'absence d'accepteur d'acide - Google Patents
Procede d'acylation d'une aniline substituee par une lactone en l'absence d'accepteur d'acideInfo
- Publication number
- FR2408601A1 FR2408601A1 FR7830402A FR7830402A FR2408601A1 FR 2408601 A1 FR2408601 A1 FR 2408601A1 FR 7830402 A FR7830402 A FR 7830402A FR 7830402 A FR7830402 A FR 7830402A FR 2408601 A1 FR2408601 A1 FR 2408601A1
- Authority
- FR
- France
- Prior art keywords
- absence
- acid acceptor
- gammabutyrolactone
- dimethylphenylamino
- lactone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
L'INVENTION CONCERNE UN PROCEDE D'ACYLATION D'UNE ANILINE SUBSTITUEE PAR UNE LACTONE EN L'ABSENCE D'ACCEPTEUR D'ACIDE. LE PROCEDE CONSISTE A FAIRE REAGIR, EN L'ABSENCE D'UN ACCEPTEUR D'ACIDE, UN HALOGENURE D'ACYLE AVEC UNE GAMMA-BUTYROLACTONE SUBSTITUEE PAR DE L'ANILINE EN PRESENCE D'UN SOLVANT NON BASIQUE, A UNE TEMPERATURE DE 65 A 150C. AINSI, ON PREPARE LA 3-(N-CHLORACETYL-N-2,6-DIMETHYLPHENYLAMINO)- GAMMABUTYROLACTONE PAR UN PROCEDE QUI CONSISTE A FAIRE ENTRER, EN L'ABSENCE D'UNE ADDITION D'ACCEPTEUR D'ACIDE, DU CHLORURE DE CHLORACETYLE EN CONTACT AVEC LA 3-(N-2,6-DIMETHYLPHENYLAMINO) GAMMABUTYROLACTONE EN PRESENCE D'UN SOLVANT ORGANIQUE NON BASIQUE, A UNE TEMPERATURE DE 65 A 150C. LA 3-(N-2,6-DIMETHYLPHENYLAMINO)- GAMMABUTYROLACTONE EST FORMEE DE PREFERENCE PAR REACTION D'A-BROMOGAMMABUTYROLACTONE AVEC LA DIMETHYLANILINE EN PRESENCE D'EAU DANS UN SOLVANT ORGANIQUE NON BASIQUE ET LA PHASE ORGANIQUE CONTENANT LA 3-(N-2,6-DIMETHYLPHENYLAMINO)- GAMMABUTYROLACTONE EST SOUMISE DIRECTEMENT, APRES SEPARATION, A L'OPERATION D'ACETYLATION. LES COMPOSES PREPARES PAR LE COMPOSE DE L'INVENTION SONT DOUES NOTAMMENT DE PROPRIETES FONGICIDES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84750477A | 1977-11-01 | 1977-11-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2408601A1 true FR2408601A1 (fr) | 1979-06-08 |
FR2408601B1 FR2408601B1 (fr) | 1983-08-12 |
Family
ID=25300794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7830402A Granted FR2408601A1 (fr) | 1977-11-01 | 1978-10-25 | Procede d'acylation d'une aniline substituee par une lactone en l'absence d'accepteur d'acide |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS5470260A (fr) |
BR (1) | BR7807190A (fr) |
CH (1) | CH639966A5 (fr) |
DE (1) | DE2847075A1 (fr) |
FR (1) | FR2408601A1 (fr) |
GB (1) | GB2006783B (fr) |
IT (1) | IT1100884B (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2407210A1 (fr) * | 1977-11-01 | 1979-05-25 | Chevron Res | Nouvelles 3-(n-acyl-n-arylamino)-gamma-butyro (thio)-lactones et leurs applications a la lutte fongicide |
FR2415634A1 (fr) * | 1978-01-28 | 1979-08-24 | Ciba Geigy Ag | Nouvelles 3-(n-hydroxyacetyl-n-phenyl)-amino-tetrahydro-2-furanones utiles comme agents microbicides |
FR2485013A1 (fr) * | 1980-06-23 | 1981-12-24 | Chevron Res | Procede de production de 3-(n-aryl-n-acylamino)-gamma-butyrothiolates et produits obtenus |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0016985A1 (fr) * | 1979-03-16 | 1980-10-15 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Anilides substitués, procédés pour leur préparation, fongicides contenant de tels composés et utilisation de tels composés ou fongicides dans la lutte contre les champignons des plantes |
US4289701A (en) * | 1979-11-13 | 1981-09-15 | Chevron Research | Lactone substituted aniline preparation |
DK13681A (da) * | 1980-01-31 | 1981-08-01 | Hoffmann La Roche | Substituerede anilider |
US4721797A (en) * | 1986-09-02 | 1988-01-26 | Ciba-Geigy Corporation | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3933860A (en) * | 1975-02-10 | 1976-01-20 | Chevron Research Company | 3-(N-acyl-N-arylamino) lactones |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH587605A5 (fr) * | 1974-04-01 | 1977-05-13 | Ciba Geigy Ag | |
US4147792A (en) * | 1977-02-04 | 1979-04-03 | Ciba-Geigy Corporation | Fungicidal compositions |
-
1978
- 1978-10-25 FR FR7830402A patent/FR2408601A1/fr active Granted
- 1978-10-28 DE DE19782847075 patent/DE2847075A1/de not_active Ceased
- 1978-10-31 JP JP13442078A patent/JPS5470260A/ja active Pending
- 1978-10-31 GB GB7842563A patent/GB2006783B/en not_active Expired
- 1978-10-31 BR BR7807190A patent/BR7807190A/pt unknown
- 1978-10-31 IT IT29299/78A patent/IT1100884B/it active
- 1978-11-01 CH CH1127378A patent/CH639966A5/de not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3933860A (en) * | 1975-02-10 | 1976-01-20 | Chevron Research Company | 3-(N-acyl-N-arylamino) lactones |
Non-Patent Citations (1)
Title |
---|
HW1958 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2407210A1 (fr) * | 1977-11-01 | 1979-05-25 | Chevron Res | Nouvelles 3-(n-acyl-n-arylamino)-gamma-butyro (thio)-lactones et leurs applications a la lutte fongicide |
FR2433524A1 (fr) * | 1977-11-01 | 1980-03-14 | Chevron Res | Nouvelles 3-(n-acyl-n-arylamino-gamma-butyrothiolactones et leurs applications a la lutte fongicide |
FR2415634A1 (fr) * | 1978-01-28 | 1979-08-24 | Ciba Geigy Ag | Nouvelles 3-(n-hydroxyacetyl-n-phenyl)-amino-tetrahydro-2-furanones utiles comme agents microbicides |
FR2485013A1 (fr) * | 1980-06-23 | 1981-12-24 | Chevron Res | Procede de production de 3-(n-aryl-n-acylamino)-gamma-butyrothiolates et produits obtenus |
Also Published As
Publication number | Publication date |
---|---|
FR2408601B1 (fr) | 1983-08-12 |
JPS5470260A (en) | 1979-06-05 |
CH639966A5 (de) | 1983-12-15 |
DE2847075A1 (de) | 1979-05-10 |
IT7829299A0 (it) | 1978-10-31 |
GB2006783A (en) | 1979-05-10 |
GB2006783B (en) | 1982-02-03 |
IT1100884B (it) | 1985-09-28 |
BR7807190A (pt) | 1979-06-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse | ||
RC | Opposition against decision of lapse | ||
DA | Annulment of decision of lapse | ||
ST | Notification of lapse | ||
ST | Notification of lapse |