FR2402658A1 - MESO-IONIC DIDEHYDROGEN DERIVATIVES OF 1,7-DIHYDRO-3H-PYRAZOLO (4,3-E) -1,2,4-TRIAZOLO (4,3-C) PYRIMIDINE-3-THIONES OR 3-ONES 1-SUBSTITUTED, AND THEIR THERAPEUTIC USE - Google Patents

MESO-IONIC DIDEHYDROGEN DERIVATIVES OF 1,7-DIHYDRO-3H-PYRAZOLO (4,3-E) -1,2,4-TRIAZOLO (4,3-C) PYRIMIDINE-3-THIONES OR 3-ONES 1-SUBSTITUTED, AND THEIR THERAPEUTIC USE

Info

Publication number
FR2402658A1
FR2402658A1 FR7826046A FR7826046A FR2402658A1 FR 2402658 A1 FR2402658 A1 FR 2402658A1 FR 7826046 A FR7826046 A FR 7826046A FR 7826046 A FR7826046 A FR 7826046A FR 2402658 A1 FR2402658 A1 FR 2402658A1
Authority
FR
France
Prior art keywords
triazolo
dihydro
derivatives
substituted
didehydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7826046A
Other languages
French (fr)
Inventor
Uwe D Treuner
Hermann Breuer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/833,103 external-priority patent/US4124764A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2402658A1 publication Critical patent/FR2402658A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne de nouveaux dérivés didéhydrogénés méso-ioniques de 1,7-dihydro-3H-pyrazoloØ4,3-eõ1,2,4-triazolo-Ø4,3-cõdyrimidine-3-thione et 3-one substitués en position 1 de formule :The invention relates to novel didehydrogenated mesoionic derivatives of 1,7-dihydro-3H-pyrazoloØ4,3-eõ1,2,4-triazolo-Ø4,3-cõdyrimidine-3-thione and 3-one substituted in position 1 of formula :

FR7826046A 1977-09-13 1978-09-11 MESO-IONIC DIDEHYDROGEN DERIVATIVES OF 1,7-DIHYDRO-3H-PYRAZOLO (4,3-E) -1,2,4-TRIAZOLO (4,3-C) PYRIMIDINE-3-THIONES OR 3-ONES 1-SUBSTITUTED, AND THEIR THERAPEUTIC USE Withdrawn FR2402658A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/833,103 US4124764A (en) 1976-04-21 1977-09-13 Meso-ionic didehydro derivatives of 1,7-dehydro-1-substituted-3H-pyrazolo[4,]-1,2,4-triazolo[4,3-c]pyrimidine-3-thiones and 3-ones

Publications (1)

Publication Number Publication Date
FR2402658A1 true FR2402658A1 (en) 1979-04-06

Family

ID=25263436

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7826046A Withdrawn FR2402658A1 (en) 1977-09-13 1978-09-11 MESO-IONIC DIDEHYDROGEN DERIVATIVES OF 1,7-DIHYDRO-3H-PYRAZOLO (4,3-E) -1,2,4-TRIAZOLO (4,3-C) PYRIMIDINE-3-THIONES OR 3-ONES 1-SUBSTITUTED, AND THEIR THERAPEUTIC USE

Country Status (13)

Country Link
JP (1) JPS5452098A (en)
AU (1) AU3914178A (en)
BE (1) BE870456A (en)
CA (1) CA1095907A (en)
DE (1) DE2838029A1 (en)
DK (1) DK402178A (en)
FR (1) FR2402658A1 (en)
GB (1) GB2004278B (en)
HU (1) HU176023B (en)
IT (1) IT1099031B (en)
NL (1) NL7809035A (en)
NO (1) NO783086L (en)
SE (1) SE7809601L (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348927A1 (en) * 1976-04-21 1977-11-18 Squibb & Sons Inc NEW PYRAZOLO (4,3-E) (1,2,4-TRIAZOLO) (4,3-C) PYRIMIDINES AND A PROCESS FOR THEIR PREPARATION

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348927A1 (en) * 1976-04-21 1977-11-18 Squibb & Sons Inc NEW PYRAZOLO (4,3-E) (1,2,4-TRIAZOLO) (4,3-C) PYRIMIDINES AND A PROCESS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
GB2004278B (en) 1982-01-13
DK402178A (en) 1979-03-14
NO783086L (en) 1979-03-14
JPS5452098A (en) 1979-04-24
AU3914178A (en) 1980-02-28
IT7827559A0 (en) 1978-09-12
IT1099031B (en) 1985-09-18
NL7809035A (en) 1979-03-15
CA1095907A (en) 1981-02-17
BE870456A (en) 1979-03-13
HU176023B (en) 1980-11-28
GB2004278A (en) 1979-03-28
SE7809601L (en) 1979-03-14
DE2838029A1 (en) 1979-03-22

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Legal Events

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