FR2387981A1 - SPIRO (INDOLINE-3,4'-PIPERIDINE) S AND RELATED COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION - Google Patents

SPIRO (INDOLINE-3,4'-PIPERIDINE) S AND RELATED COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Info

Publication number
FR2387981A1
FR2387981A1 FR7811909A FR7811909A FR2387981A1 FR 2387981 A1 FR2387981 A1 FR 2387981A1 FR 7811909 A FR7811909 A FR 7811909A FR 7811909 A FR7811909 A FR 7811909A FR 2387981 A1 FR2387981 A1 FR 2387981A1
Authority
FR
France
Prior art keywords
indoline
spiro
piperidine
preparation
related compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7811909A
Other languages
French (fr)
Other versions
FR2387981B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2387981A1 publication Critical patent/FR2387981A1/en
Application granted granted Critical
Publication of FR2387981B1 publication Critical patent/FR2387981B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

L'invention a pour objet des spiro(indoline-3,4'-pipéridine)s de formule :The invention relates to spiro (indoline-3,4'-piperidine) s of formula:

FR7811909A 1977-04-21 1978-04-21 SPIRO (INDOLINE-3,4'-PIPERIDINE) S AND RELATED COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Granted FR2387981A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78972377A 1977-04-21 1977-04-21

Publications (2)

Publication Number Publication Date
FR2387981A1 true FR2387981A1 (en) 1978-11-17
FR2387981B1 FR2387981B1 (en) 1980-08-29

Family

ID=25148495

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7811909A Granted FR2387981A1 (en) 1977-04-21 1978-04-21 SPIRO (INDOLINE-3,4'-PIPERIDINE) S AND RELATED COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Country Status (17)

Country Link
JP (1) JPS53132578A (en)
AU (1) AU523799B2 (en)
BE (1) BE866254A (en)
CA (1) CA1105025A (en)
DE (1) DE2816380A1 (en)
DK (1) DK173678A (en)
EG (1) EG13581A (en)
ES (1) ES468860A1 (en)
FI (1) FI781208A (en)
FR (1) FR2387981A1 (en)
GB (1) GB1603030A (en)
IL (1) IL54538A0 (en)
NL (1) NL7804246A (en)
NZ (1) NZ187015A (en)
PH (1) PH13590A (en)
SE (1) SE7804590L (en)
ZA (1) ZA782273B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307235A (en) * 1978-08-23 1981-12-22 American Hoechst Corporation Spiro[indoline-3,4'-piperidine]s
US4477667A (en) * 1980-02-15 1984-10-16 American Hoechst Corporation Spiro[indoline-3,4'-piperidine]s and related compounds
DE3300522A1 (en) * 1982-01-21 1983-07-28 Sandoz-Patent-GmbH, 7850 Lörrach 3,3-DIALKYL AND 3,3-ALKYLENE INDOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
AU2223495A (en) * 1994-04-15 1995-11-10 Yamanouchi Pharmaceutical Co., Ltd. Spiro compound and medicinal composition thereof
WO1996033189A1 (en) * 1995-04-19 1996-10-24 Merck & Co., Inc. Process for the preparation of spiroindolines
WO1998051687A1 (en) * 1997-05-14 1998-11-19 Fujisawa Pharmaceutical Co., Ltd. Piperidino derivatives which promote growth hormone release
GB0213715D0 (en) 2002-06-14 2002-07-24 Syngenta Ltd Chemical compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299075A (en) * 1964-03-12 1967-01-17 Smith Kline French Lab Spiro [3h-indole-3, 3'-pyrrolidine and piperidine] derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299075A (en) * 1964-03-12 1967-01-17 Smith Kline French Lab Spiro [3h-indole-3, 3'-pyrrolidine and piperidine] derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NV2054/76 *

Also Published As

Publication number Publication date
SE7804590L (en) 1978-10-22
IL54538A0 (en) 1978-07-31
EG13581A (en) 1981-12-31
DE2816380A1 (en) 1978-12-07
FI781208A (en) 1978-10-22
JPS53132578A (en) 1978-11-18
AU523799B2 (en) 1982-08-19
CA1105025A (en) 1981-07-14
ES468860A1 (en) 1979-09-16
BE866254A (en) 1978-10-23
GB1603030A (en) 1981-11-18
ZA782273B (en) 1979-04-25
NZ187015A (en) 1981-04-24
DK173678A (en) 1978-10-22
NL7804246A (en) 1978-10-24
PH13590A (en) 1980-07-16
AU3528678A (en) 1979-10-25
FR2387981B1 (en) 1980-08-29

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Legal Events

Date Code Title Description
ST Notification of lapse