FR2401162A1 - ANTIBIOTIC DERIVED FROM A STREPTOMYCE, USED AS A MEDICINAL PRODUCT - Google Patents
ANTIBIOTIC DERIVED FROM A STREPTOMYCE, USED AS A MEDICINAL PRODUCTInfo
- Publication number
- FR2401162A1 FR2401162A1 FR7806154A FR7806154A FR2401162A1 FR 2401162 A1 FR2401162 A1 FR 2401162A1 FR 7806154 A FR7806154 A FR 7806154A FR 7806154 A FR7806154 A FR 7806154A FR 2401162 A1 FR2401162 A1 FR 2401162A1
- Authority
- FR
- France
- Prior art keywords
- compounds
- salts
- streptomyce
- medicinal product
- formulae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The novel derivatives are compounds of the formulae I and II and their salts. These compounds are prepared by culturing Streptomyces olivaceus or Streptomyces gedanensis and recovering the compounds formed and/or their salts from the culture medium. Microorganisms preferred for the culture are the strains ATCC 31126 and 31365. The novel compounds of the formulae I and II and their salts exhibit antibacterial action and are employed as active component in medicaments, on their own or in combination with other antibiotics, preferably in the form of an individual, isolated salt.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9366/77A GB1601688A (en) | 1977-03-05 | 1977-03-05 | 6-(1-hydroxyethyl)-7-oxo 1-aza bicyclo (3,2,0)-hept-2-ene-2-carboxylic acid derivatives and their use in pharmaceutical compositions |
GB3283677 | 1977-08-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2401162A1 true FR2401162A1 (en) | 1979-03-23 |
FR2401162B1 FR2401162B1 (en) | 1980-08-29 |
Family
ID=26242889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7806154A Granted FR2401162A1 (en) | 1977-03-05 | 1978-03-03 | ANTIBIOTIC DERIVED FROM A STREPTOMYCE, USED AS A MEDICINAL PRODUCT |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS53116396A (en) |
AU (1) | AU525142B2 (en) |
CH (1) | CH641805A5 (en) |
DE (1) | DE2808563A1 (en) |
DK (1) | DK98478A (en) |
ES (1) | ES467562A1 (en) |
FR (1) | FR2401162A1 (en) |
IE (1) | IE46736B1 (en) |
IT (1) | IT7848280A0 (en) |
NL (1) | NL7802356A (en) |
SE (1) | SE7802462L (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4162323A (en) * | 1977-04-18 | 1979-07-24 | Merck & Co., Inc. | Antibiotic N-acetyl-dehydro-thienamycin |
EP0008885B1 (en) * | 1978-09-09 | 1983-11-30 | Beecham Group Plc | Beta-lactam compounds, their preparation and use |
EP0033209B1 (en) * | 1980-01-25 | 1984-06-13 | Beecham Group Plc | Beta-lactam containing compounds, their preparation and use |
IN155384B (en) * | 1980-05-14 | 1985-01-19 | Pfizer | |
JP4977670B2 (en) * | 2008-09-11 | 2012-07-18 | 啓司 関口 | Fresh flower shaping device |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2332018A1 (en) * | 1975-11-21 | 1977-06-17 | Merck & Co Inc | NEW ANTIBIOTIC SUBSTANCE, N-ACETYL THIENAMYCIN |
FR2332017A1 (en) * | 1975-11-21 | 1977-06-17 | Merck & Co Inc | THIENAMYCIN-TYPE ANTIBIOTICS USEFUL AS MEDICINAL PRODUCTS |
FR2349586A1 (en) * | 1976-04-28 | 1977-11-25 | Merck & Co Inc | NEW ANTIBIOTICS IN THE THIENAMYCIN FAMILY |
-
1978
- 1978-02-28 DE DE19782808563 patent/DE2808563A1/en not_active Withdrawn
- 1978-03-03 JP JP2437578A patent/JPS53116396A/en active Pending
- 1978-03-03 NL NL7802356A patent/NL7802356A/en not_active Application Discontinuation
- 1978-03-03 IE IE443/78A patent/IE46736B1/en unknown
- 1978-03-03 IT IT7848280A patent/IT7848280A0/en unknown
- 1978-03-03 SE SE7802462A patent/SE7802462L/en unknown
- 1978-03-03 FR FR7806154A patent/FR2401162A1/en active Granted
- 1978-03-03 ES ES467562A patent/ES467562A1/en not_active Expired
- 1978-03-03 CH CH233978A patent/CH641805A5/en not_active IP Right Cessation
- 1978-03-03 AU AU33841/78A patent/AU525142B2/en not_active Expired
- 1978-03-03 DK DK98478A patent/DK98478A/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2332018A1 (en) * | 1975-11-21 | 1977-06-17 | Merck & Co Inc | NEW ANTIBIOTIC SUBSTANCE, N-ACETYL THIENAMYCIN |
FR2332017A1 (en) * | 1975-11-21 | 1977-06-17 | Merck & Co Inc | THIENAMYCIN-TYPE ANTIBIOTICS USEFUL AS MEDICINAL PRODUCTS |
FR2349586A1 (en) * | 1976-04-28 | 1977-11-25 | Merck & Co Inc | NEW ANTIBIOTICS IN THE THIENAMYCIN FAMILY |
Also Published As
Publication number | Publication date |
---|---|
JPS53116396A (en) | 1978-10-11 |
AU525142B2 (en) | 1982-10-21 |
DE2808563A1 (en) | 1978-09-07 |
FR2401162B1 (en) | 1980-08-29 |
ES467562A1 (en) | 1980-05-16 |
DK98478A (en) | 1978-09-06 |
IE46736B1 (en) | 1983-09-07 |
CH641805A5 (en) | 1984-03-15 |
IT7848280A0 (en) | 1978-03-03 |
SE7802462L (en) | 1978-09-06 |
IE780443L (en) | 1978-09-05 |
NL7802356A (en) | 1978-09-07 |
AU3384178A (en) | 1979-09-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |