FR2401162A1 - ANTIBIOTIC DERIVED FROM A STREPTOMYCE, USED AS A MEDICINAL PRODUCT - Google Patents

ANTIBIOTIC DERIVED FROM A STREPTOMYCE, USED AS A MEDICINAL PRODUCT

Info

Publication number
FR2401162A1
FR2401162A1 FR7806154A FR7806154A FR2401162A1 FR 2401162 A1 FR2401162 A1 FR 2401162A1 FR 7806154 A FR7806154 A FR 7806154A FR 7806154 A FR7806154 A FR 7806154A FR 2401162 A1 FR2401162 A1 FR 2401162A1
Authority
FR
France
Prior art keywords
compounds
salts
streptomyce
medicinal product
formulae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7806154A
Other languages
French (fr)
Other versions
FR2401162B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9366/77A external-priority patent/GB1601688A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of FR2401162A1 publication Critical patent/FR2401162A1/en
Application granted granted Critical
Publication of FR2401162B1 publication Critical patent/FR2401162B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

The novel derivatives are compounds of the formulae I and II and their salts. These compounds are prepared by culturing Streptomyces olivaceus or Streptomyces gedanensis and recovering the compounds formed and/or their salts from the culture medium. Microorganisms preferred for the culture are the strains ATCC 31126 and 31365. The novel compounds of the formulae I and II and their salts exhibit antibacterial action and are employed as active component in medicaments, on their own or in combination with other antibiotics, preferably in the form of an individual, isolated salt.
FR7806154A 1977-03-05 1978-03-03 ANTIBIOTIC DERIVED FROM A STREPTOMYCE, USED AS A MEDICINAL PRODUCT Granted FR2401162A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9366/77A GB1601688A (en) 1977-03-05 1977-03-05 6-(1-hydroxyethyl)-7-oxo 1-aza bicyclo (3,2,0)-hept-2-ene-2-carboxylic acid derivatives and their use in pharmaceutical compositions
GB3283677 1977-08-05

Publications (2)

Publication Number Publication Date
FR2401162A1 true FR2401162A1 (en) 1979-03-23
FR2401162B1 FR2401162B1 (en) 1980-08-29

Family

ID=26242889

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7806154A Granted FR2401162A1 (en) 1977-03-05 1978-03-03 ANTIBIOTIC DERIVED FROM A STREPTOMYCE, USED AS A MEDICINAL PRODUCT

Country Status (11)

Country Link
JP (1) JPS53116396A (en)
AU (1) AU525142B2 (en)
CH (1) CH641805A5 (en)
DE (1) DE2808563A1 (en)
DK (1) DK98478A (en)
ES (1) ES467562A1 (en)
FR (1) FR2401162A1 (en)
IE (1) IE46736B1 (en)
IT (1) IT7848280A0 (en)
NL (1) NL7802356A (en)
SE (1) SE7802462L (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162323A (en) * 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
EP0008885B1 (en) * 1978-09-09 1983-11-30 Beecham Group Plc Beta-lactam compounds, their preparation and use
DE3164021D1 (en) * 1980-01-25 1984-07-19 Beecham Group Plc Beta-lactam containing compounds, their preparation and use
IN155384B (en) * 1980-05-14 1985-01-19 Pfizer
JP4977670B2 (en) * 2008-09-11 2012-07-18 啓司 関口 Fresh flower shaping device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2332017A1 (en) * 1975-11-21 1977-06-17 Merck & Co Inc THIENAMYCIN-TYPE ANTIBIOTICS USEFUL AS MEDICINAL PRODUCTS
FR2332018A1 (en) * 1975-11-21 1977-06-17 Merck & Co Inc NEW ANTIBIOTIC SUBSTANCE, N-ACETYL THIENAMYCIN
FR2349586A1 (en) * 1976-04-28 1977-11-25 Merck & Co Inc NEW ANTIBIOTICS IN THE THIENAMYCIN FAMILY

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2332017A1 (en) * 1975-11-21 1977-06-17 Merck & Co Inc THIENAMYCIN-TYPE ANTIBIOTICS USEFUL AS MEDICINAL PRODUCTS
FR2332018A1 (en) * 1975-11-21 1977-06-17 Merck & Co Inc NEW ANTIBIOTIC SUBSTANCE, N-ACETYL THIENAMYCIN
FR2349586A1 (en) * 1976-04-28 1977-11-25 Merck & Co Inc NEW ANTIBIOTICS IN THE THIENAMYCIN FAMILY

Also Published As

Publication number Publication date
NL7802356A (en) 1978-09-07
ES467562A1 (en) 1980-05-16
IE780443L (en) 1978-09-05
JPS53116396A (en) 1978-10-11
AU525142B2 (en) 1982-10-21
DE2808563A1 (en) 1978-09-07
AU3384178A (en) 1979-09-06
IT7848280A0 (en) 1978-03-03
IE46736B1 (en) 1983-09-07
SE7802462L (en) 1978-09-06
FR2401162B1 (en) 1980-08-29
CH641805A5 (en) 1984-03-15
DK98478A (en) 1978-09-06

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Legal Events

Date Code Title Description
ST Notification of lapse