FR2401152A1 - Nouveaux thienyloxamates, leur procede de preparation et medicaments anti-allergiques les contenant - Google Patents
Nouveaux thienyloxamates, leur procede de preparation et medicaments anti-allergiques les contenantInfo
- Publication number
- FR2401152A1 FR2401152A1 FR7821764A FR7821764A FR2401152A1 FR 2401152 A1 FR2401152 A1 FR 2401152A1 FR 7821764 A FR7821764 A FR 7821764A FR 7821764 A FR7821764 A FR 7821764A FR 2401152 A1 FR2401152 A1 FR 2401152A1
- Authority
- FR
- France
- Prior art keywords
- thienyl
- low toxicity
- oxamate
- antiallergic agents
- amino carbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
L'invention concerne une nouvelle série de thiényloxamates ainsi que leur procédé de préparation. Des 2-amino-thiophène-3-carboxamides sont transformés en oxamates ou en fumaramides par acylation du groupe amino. Les composés de l'invention sont doués d'activité anti-allergique ; ils exercent une action inhibitrice sur la réaction d'hypersensibilité immédiate chez les mammifères.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/826,591 US4159377A (en) | 1975-09-10 | 1977-08-22 | Selected thieno[2,3-d]pyrimidines |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2401152A1 true FR2401152A1 (fr) | 1979-03-23 |
FR2401152B1 FR2401152B1 (fr) | 1982-04-02 |
Family
ID=25246995
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7731213A Granted FR2401163A1 (fr) | 1977-08-22 | 1977-10-17 | Nouvelles thieno(2,3-d)pyrimidines, leur procede de preparation et medicament anti-allergique les contenant |
FR7821764A Granted FR2401152A1 (fr) | 1977-08-22 | 1978-07-21 | Nouveaux thienyloxamates, leur procede de preparation et medicaments anti-allergiques les contenant |
FR7821765A Granted FR2401164A1 (fr) | 1977-08-22 | 1978-07-21 | Nouvelles thieno-oxazines et medicament anti-allergique les contenant |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7731213A Granted FR2401163A1 (fr) | 1977-08-22 | 1977-10-17 | Nouvelles thieno(2,3-d)pyrimidines, leur procede de preparation et medicament anti-allergique les contenant |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7821765A Granted FR2401164A1 (fr) | 1977-08-22 | 1978-07-21 | Nouvelles thieno-oxazines et medicament anti-allergique les contenant |
Country Status (2)
Country | Link |
---|---|
CA (1) | CA1094063A (fr) |
FR (3) | FR2401163A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0234557A1 (fr) * | 1986-02-25 | 1987-09-02 | Merrell Dow Pharmaceuticals Inc. | 3-(1H-tétrazol-5-yl)thiéno[2,3-d]pyrimidin-4(3H)-ones |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9426021D0 (en) * | 1994-12-22 | 1995-02-22 | Smithkline Beecham Plc | Pharmaceuticals |
AU1595997A (en) * | 1996-01-26 | 1997-08-20 | Smithkline Beecham Plc | Thienoxazinone derivatives useful as antiviral agents |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2035767A1 (fr) * | 1969-03-07 | 1970-12-24 | Centre Etd Ind Pharma | |
US3963750A (en) * | 1973-08-09 | 1976-06-15 | Beecham Group Limited | Thiophene derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2121341A1 (en) * | 1971-01-04 | 1972-08-25 | Ferlux | 2-substd-3,1-benzoxazin-4-ones - antiinflammatories, analgesics sedatives and diuretics |
BE859818A (fr) * | 1977-10-17 | 1978-04-17 | Bristol Myers Co | Thieno(2,3-d)pyrimidines antiallergiques |
-
1977
- 1977-10-17 CA CA288,853A patent/CA1094063A/fr not_active Expired
- 1977-10-17 FR FR7731213A patent/FR2401163A1/fr active Granted
-
1978
- 1978-07-21 FR FR7821764A patent/FR2401152A1/fr active Granted
- 1978-07-21 FR FR7821765A patent/FR2401164A1/fr active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2035767A1 (fr) * | 1969-03-07 | 1970-12-24 | Centre Etd Ind Pharma | |
US3963750A (en) * | 1973-08-09 | 1976-06-15 | Beecham Group Limited | Thiophene derivatives |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0234557A1 (fr) * | 1986-02-25 | 1987-09-02 | Merrell Dow Pharmaceuticals Inc. | 3-(1H-tétrazol-5-yl)thiéno[2,3-d]pyrimidin-4(3H)-ones |
Also Published As
Publication number | Publication date |
---|---|
FR2401163B1 (fr) | 1982-04-02 |
CA1094063A (fr) | 1981-01-20 |
FR2401163A1 (fr) | 1979-03-23 |
FR2401152B1 (fr) | 1982-04-02 |
FR2401164A1 (fr) | 1979-03-23 |
FR2401164B1 (fr) | 1982-04-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |