FR2399993A1 - Composition pour le traitement de l'hypertension a base d'un alcool polyprenylique ou d'un de ses esters - Google Patents

Composition pour le traitement de l'hypertension a base d'un alcool polyprenylique ou d'un de ses esters

Info

Publication number
FR2399993A1
FR2399993A1 FR7823571A FR7823571A FR2399993A1 FR 2399993 A1 FR2399993 A1 FR 2399993A1 FR 7823571 A FR7823571 A FR 7823571A FR 7823571 A FR7823571 A FR 7823571A FR 2399993 A1 FR2399993 A1 FR 2399993A1
Authority
FR
France
Prior art keywords
esters
treatment
composition
hypertension based
polyprenyl alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7823571A
Other languages
English (en)
Other versions
FR2399993B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9496577A external-priority patent/JPS5432632A/ja
Priority claimed from JP13300877A external-priority patent/JPS5467037A/ja
Priority claimed from JP13944377A external-priority patent/JPS5476513A/ja
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of FR2399993A1 publication Critical patent/FR2399993A1/fr
Application granted granted Critical
Publication of FR2399993B1 publication Critical patent/FR2399993B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/04—Acyclic alcohols with carbon-to-carbon triple bonds
    • C07C33/048—Acyclic alcohols with carbon-to-carbon triple bonds with double and triple bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention a pour objet une composition pour le traitement de l'hypertension contenant, à titre de principe actif, un alcool polyprénylique ou un de ses esters, répondant à la formule :
FR7823571A 1977-08-10 1978-08-10 Composition pour le traitement de l'hypertension a base d'un alcool polyprenylique ou d'un de ses esters Granted FR2399993A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP9496577A JPS5432632A (en) 1977-08-10 1977-08-10 Depressors containing polyprenyl alcohols
JP13300877A JPS5467037A (en) 1977-11-08 1977-11-08 Hypotensive agent containing polyprenyl alcohol as main component
JP13944377A JPS5476513A (en) 1977-11-22 1977-11-22 Polyprenyl alcohol ester and hypotensives containing it

Publications (2)

Publication Number Publication Date
FR2399993A1 true FR2399993A1 (fr) 1979-03-09
FR2399993B1 FR2399993B1 (fr) 1983-11-18

Family

ID=27307697

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7823571A Granted FR2399993A1 (fr) 1977-08-10 1978-08-10 Composition pour le traitement de l'hypertension a base d'un alcool polyprenylique ou d'un de ses esters

Country Status (3)

Country Link
DE (1) DE2834911C2 (fr)
FR (1) FR2399993A1 (fr)
GB (1) GB2002231B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318989A1 (de) * 1982-05-28 1983-12-01 Eisai Co., Ltd., Tokyo Ss,(gamma)-dihydropolyprenylalkoholderivate und arzneimittel, welche diese enthalten

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1179929A (fr) * 1954-05-11 1959-05-29 Hoffmann La Roche Procédé de préparation d'esters d'alcools tertiaires oléfiniques
FR1341487A (fr) * 1959-10-09 1963-11-02 Hoffmann La Roche Procédé pour la préparation de dériés de 2, 3-diméthoxy-5-méthyl-benzohydroquinone-(1, 4)
DE2019835A1 (de) * 1969-04-24 1970-11-12 Nisshin Flour Milling Co Verfahren zur Herstellung von Solanesol
FR2332009A1 (fr) * 1975-11-18 1977-06-17 Sankyo Co Nouveaux derives polyprenyliques, leur procede de preparation et leurs applications

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52144614A (en) * 1976-05-27 1977-12-02 Eisai Co Ltd Polyprenyl carboxylic acid compounds and hypo-tensor containing same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1179929A (fr) * 1954-05-11 1959-05-29 Hoffmann La Roche Procédé de préparation d'esters d'alcools tertiaires oléfiniques
FR1341487A (fr) * 1959-10-09 1963-11-02 Hoffmann La Roche Procédé pour la préparation de dériés de 2, 3-diméthoxy-5-méthyl-benzohydroquinone-(1, 4)
DE2019835A1 (de) * 1969-04-24 1970-11-12 Nisshin Flour Milling Co Verfahren zur Herstellung von Solanesol
FR2332009A1 (fr) * 1975-11-18 1977-06-17 Sankyo Co Nouveaux derives polyprenyliques, leur procede de preparation et leurs applications

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ABJP/70 *
CA1967 *
CA1971 *
CA1977 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318989A1 (de) * 1982-05-28 1983-12-01 Eisai Co., Ltd., Tokyo Ss,(gamma)-dihydropolyprenylalkoholderivate und arzneimittel, welche diese enthalten
FR2532844A1 (fr) * 1982-05-28 1984-03-16 Eisai Co Ltd Composition pharmaceutique contenant un compose polyprenylique
FR2569108A1 (fr) * 1982-05-28 1986-02-21 Eisai Co Ltd Composition pharmaceutique contenant un compose polyprenylique

Also Published As

Publication number Publication date
FR2399993B1 (fr) 1983-11-18
GB2002231A (en) 1979-02-21
DE2834911A1 (de) 1979-03-01
GB2002231B (en) 1982-03-17
DE2834911C2 (de) 1985-11-21

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Legal Events

Date Code Title Description
ST Notification of lapse