FR2399432A1 - Cephalosporines, leurs procedes de preparation et leur utilisation comme agents therapeutiques - Google Patents

Cephalosporines, leurs procedes de preparation et leur utilisation comme agents therapeutiques

Info

Publication number
FR2399432A1
FR2399432A1 FR7823018A FR7823018A FR2399432A1 FR 2399432 A1 FR2399432 A1 FR 2399432A1 FR 7823018 A FR7823018 A FR 7823018A FR 7823018 A FR7823018 A FR 7823018A FR 2399432 A1 FR2399432 A1 FR 2399432A1
Authority
FR
France
Prior art keywords
cephalosporins
therapeutic agents
preparation methods
øcarbamoyloximino
acetamidoõ
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7823018A
Other languages
English (en)
Other versions
FR2399432B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2399432A1 publication Critical patent/FR2399432A1/fr
Application granted granted Critical
Publication of FR2399432B1 publication Critical patent/FR2399432B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention décrit de nouvelles Ø2-(syn)- Øcarbamoyloximino-acétamidoõ céphalosporines correspondant à la formule :
FR7823018A 1977-08-06 1978-08-03 Cephalosporines, leurs procedes de preparation et leur utilisation comme agents therapeutiques Granted FR2399432A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52094469A JPS609719B2 (ja) 1977-08-06 1977-08-06 セフアロスポリン誘導体およびその製造法

Publications (2)

Publication Number Publication Date
FR2399432A1 true FR2399432A1 (fr) 1979-03-02
FR2399432B1 FR2399432B1 (fr) 1982-10-08

Family

ID=14111131

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7823018A Granted FR2399432A1 (fr) 1977-08-06 1978-08-03 Cephalosporines, leurs procedes de preparation et leur utilisation comme agents therapeutiques

Country Status (6)

Country Link
US (1) US4200575A (fr)
JP (1) JPS609719B2 (fr)
CH (1) CH641467A5 (fr)
DE (1) DE2834097A1 (fr)
FR (1) FR2399432A1 (fr)
GB (1) GB2002761B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2967356D1 (en) 1978-07-17 1985-02-28 Fujisawa Pharmaceutical Co Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
IL61458A0 (en) * 1979-12-07 1980-12-31 Erba Farmitalia N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
US4252802A (en) * 1980-03-13 1981-02-24 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
IL63965A (en) * 1980-10-10 1985-01-31 Sparamedica Ag 7-(2-(2-amino-4-selenazoyl)acetamido)cephalosporin derivatives,and intermediates therefor,their preparation and pharmaceutical compositions containing them
US4367228A (en) * 1980-10-29 1983-01-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compound and composition
US4396619A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin betaines
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins
US4402955A (en) * 1981-10-02 1983-09-06 Eli Lilly And Company Dioximino cephalosporin antibiotics
US4379787A (en) * 1981-10-02 1983-04-12 Eli Lilly And Company Oximino-substituted cephalosporin compounds
US4450270A (en) * 1981-10-02 1984-05-22 Eli Lilly And Company Dioximino cephalosporin antibiotics
US4388316A (en) * 1981-10-02 1983-06-14 Eli Lilly And Company Amino-substituted oxazole, oxadiazole and isoxazole-substituted cephalosporins
ES522549A0 (es) * 1982-05-20 1984-08-16 Glaxo Group Ltd Un procedimiento para la preparacion de un derivado de cefalosporina.
US4690921A (en) * 1983-10-11 1987-09-01 Yamanouchi Pharmaceutical Co., Ltd. Cephalosporin compounds and salts thereof
DE3585434D1 (de) * 1984-12-27 1992-04-02 Banyu Pharma Co Ltd Cephalosporinverbindungen.
AU586215B2 (en) * 1985-01-21 1989-07-06 Nippon Pharmaceutical Development Institute Company Limited Novel ```-lactam antibiotics
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
US20130065874A1 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
KR102226197B1 (ko) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
AU2014233637A1 (en) 2013-09-09 2015-03-26 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024134A (en) * 1971-01-29 1977-05-17 Glaxo Laboratories Limited Syn isomers of cephalosporins having α-hydroximino- or α-acyloxyiminoacylamido groups at position-7
US4024137A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf

Also Published As

Publication number Publication date
DE2834097A1 (de) 1979-02-22
GB2002761B (en) 1982-06-16
US4200575A (en) 1980-04-29
JPS5430194A (en) 1979-03-06
FR2399432B1 (fr) 1982-10-08
JPS609719B2 (ja) 1985-03-12
CH641467A5 (de) 1984-02-29
GB2002761A (en) 1979-02-28

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Legal Events

Date Code Title Description
ST Notification of lapse