FR2384781A2 - Nouvelles oximes derivees de l'article 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments - Google Patents
Nouvelles oximes derivees de l'article 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicamentsInfo
- Publication number
- FR2384781A2 FR2384781A2 FR7701713A FR7701713A FR2384781A2 FR 2384781 A2 FR2384781 A2 FR 2384781A2 FR 7701713 A FR7701713 A FR 7701713A FR 7701713 A FR7701713 A FR 7701713A FR 2384781 A2 FR2384781 A2 FR 2384781A2
- Authority
- FR
- France
- Prior art keywords
- thiazolyl
- acetamido
- cephalosporanic acid
- isomers
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NYBWUHOMYZZKOR-UHFFFAOYSA-N tes-adt Chemical class C1=C2C(C#C[Si](CC)(CC)CC)=C(C=C3C(SC=C3)=C3)C3=C(C#C[Si](CC)(CC)CC)C2=CC2=C1SC=C2 NYBWUHOMYZZKOR-UHFFFAOYSA-N 0.000 title abstract 2
- 241000894006 Bacteria Species 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 title 1
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 6
- SJRJJKPEHAURKC-UHFFFAOYSA-N N-Methylmorpholine Chemical compound CN1CCOCC1 SJRJJKPEHAURKC-UHFFFAOYSA-N 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- -1 amine salts Chemical class 0.000 abstract 2
- LWRXBZDYMOWJEV-UHFFFAOYSA-N 2-ethoxyimino-2-[2-(tritylamino)-1,3-thiazol-4-yl]acetic acid Chemical compound CCON=C(C(O)=O)C1=CSC(NC(C=2C=CC=CC=2)(C=2C=CC=CC=2)C=2C=CC=CC=2)=N1 LWRXBZDYMOWJEV-UHFFFAOYSA-N 0.000 abstract 1
- YOETUEMZNOLGDB-UHFFFAOYSA-N 2-methylpropyl carbonochloridate Chemical compound CC(C)COC(Cl)=O YOETUEMZNOLGDB-UHFFFAOYSA-N 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7701713A FR2384781A2 (fr) | 1977-01-21 | 1977-01-21 | Nouvelles oximes derivees de l'article 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7701713A FR2384781A2 (fr) | 1977-01-21 | 1977-01-21 | Nouvelles oximes derivees de l'article 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2384781A2 true FR2384781A2 (fr) | 1978-10-20 |
| FR2384781B2 FR2384781B2 (cs) | 1980-04-11 |
Family
ID=9185771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7701713A Granted FR2384781A2 (fr) | 1977-01-21 | 1977-01-21 | Nouvelles oximes derivees de l'article 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2384781A2 (cs) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0155103A3 (en) * | 1984-02-24 | 1986-07-23 | Kureha Kagaku Kogyo Kabushiki Kaisha | Cephalosporin derivatives |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH642957A5 (de) | 1980-02-18 | 1984-05-15 | Lonza Ag | Verfahren zur herstellung von (2-aminothiazol-4-yl)-essigsaeure-hydrochlorid. |
-
1977
- 1977-01-21 FR FR7701713A patent/FR2384781A2/fr active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0155103A3 (en) * | 1984-02-24 | 1986-07-23 | Kureha Kagaku Kogyo Kabushiki Kaisha | Cephalosporin derivatives |
| US4734409A (en) * | 1984-02-24 | 1988-03-29 | Kureha Kagaku Kogyo Kabushiki Kaisha | Cephalosporin derivative, process for producing the same and pharmaceutical composition containing the same |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2384781B2 (cs) | 1980-04-11 |
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