FR2374326A1 - Procede pour la preparation des cephalosporines a partir de l'acide 7-aminocephalosporanique et de l'acide 7-amino-desacetoxycephalosporanique - Google Patents
Procede pour la preparation des cephalosporines a partir de l'acide 7-aminocephalosporanique et de l'acide 7-amino-desacetoxycephalosporaniqueInfo
- Publication number
- FR2374326A1 FR2374326A1 FR7737985A FR7737985A FR2374326A1 FR 2374326 A1 FR2374326 A1 FR 2374326A1 FR 7737985 A FR7737985 A FR 7737985A FR 7737985 A FR7737985 A FR 7737985A FR 2374326 A1 FR2374326 A1 FR 2374326A1
- Authority
- FR
- France
- Prior art keywords
- acid
- cephalosporins
- preparation
- amino
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 3
- 229940124587 cephalosporin Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 title 1
- NVIAYEIXYQCDAN-CLZZGJSISA-N 7beta-aminodeacetoxycephalosporanic acid Chemical compound S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](N)[C@@H]12 NVIAYEIXYQCDAN-CLZZGJSISA-N 0.000 title 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052796 boron Inorganic materials 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
- C07D501/06—Acylation of 7-aminocephalosporanic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT30482A/76A IT1065387B (it) | 1976-12-16 | 1976-12-16 | Proccedimento per la preparazione di cefalosporine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2374326A1 true FR2374326A1 (fr) | 1978-07-13 |
| FR2374326B1 FR2374326B1 (enExample) | 1983-01-14 |
Family
ID=11229809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7737985A Granted FR2374326A1 (fr) | 1976-12-16 | 1977-12-16 | Procede pour la preparation des cephalosporines a partir de l'acide 7-aminocephalosporanique et de l'acide 7-amino-desacetoxycephalosporanique |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4139702A (enExample) |
| JP (1) | JPS5398990A (enExample) |
| CA (1) | CA1077029A (enExample) |
| DE (1) | DE2755902A1 (enExample) |
| FR (1) | FR2374326A1 (enExample) |
| IL (1) | IL53624A (enExample) |
| IT (1) | IT1065387B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004083172A2 (en) * | 2003-03-21 | 2004-09-30 | Ranbaxy Laboratories Limited | Process for the preparation of 7-amino (p-hydroxyphenylglyclyamido) cephem compounds |
| LT1641933T (lt) * | 2003-07-03 | 2018-04-10 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Cefradino gamybos būdas |
| US20070072945A1 (en) * | 2004-03-31 | 2007-03-29 | Pohoreski Anton | Sulphur-containing oils for controlling plant pathogens and stimulating nutrient uptake |
| US20080281093A1 (en) * | 2004-11-01 | 2008-11-13 | Bandi Parthasaradhi Reddy | Novel Process For Preparation of Cefprozil Intermediate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4051131A (en) * | 1972-11-29 | 1977-09-27 | American Home Products Corporation (Del.) | Intermediates for preparing cephalosporins |
| US3988326A (en) * | 1974-02-22 | 1976-10-26 | Meiji Seika Kaisha, Ltd. | Process for N-acylation of 7 amino cephem compounds |
| DE2440268A1 (de) * | 1974-08-22 | 1976-03-04 | Bayer Ag | Beta-lactamantibiotika, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1976
- 1976-12-16 IT IT30482A/76A patent/IT1065387B/it active
-
1977
- 1977-03-29 JP JP3514677A patent/JPS5398990A/ja active Pending
- 1977-12-12 US US05/859,526 patent/US4139702A/en not_active Expired - Lifetime
- 1977-12-15 CA CA293,174A patent/CA1077029A/en not_active Expired
- 1977-12-15 IL IL53624A patent/IL53624A/xx unknown
- 1977-12-15 DE DE19772755902 patent/DE2755902A1/de not_active Withdrawn
- 1977-12-16 FR FR7737985A patent/FR2374326A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IL53624A (en) | 1980-11-30 |
| CA1077029A (en) | 1980-05-06 |
| IT1065387B (it) | 1985-02-25 |
| JPS5398990A (en) | 1978-08-29 |
| US4139702A (en) | 1979-02-13 |
| IL53624A0 (en) | 1978-03-10 |
| FR2374326B1 (enExample) | 1983-01-14 |
| DE2755902A1 (de) | 1978-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |