FR2374309B1 - - Google Patents

Info

Publication number
FR2374309B1
FR2374309B1 FR7738009A FR7738009A FR2374309B1 FR 2374309 B1 FR2374309 B1 FR 2374309B1 FR 7738009 A FR7738009 A FR 7738009A FR 7738009 A FR7738009 A FR 7738009A FR 2374309 B1 FR2374309 B1 FR 2374309B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7738009A
Other versions
FR2374309A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB52955/76A external-priority patent/GB1598662A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of FR2374309A1 publication Critical patent/FR2374309A1/fr
Application granted granted Critical
Publication of FR2374309B1 publication Critical patent/FR2374309B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7738009A 1976-12-18 1977-12-16 Compose a cycle diazole utilisable comme medicament Granted FR2374309A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB52955/76A GB1598662A (en) 1976-12-18 1976-12-18 10,12-diazoprostaglandins
GB3036977 1977-07-20

Publications (2)

Publication Number Publication Date
FR2374309A1 FR2374309A1 (fr) 1978-07-13
FR2374309B1 true FR2374309B1 (fr) 1980-05-16

Family

ID=26260409

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7738009A Granted FR2374309A1 (fr) 1976-12-18 1977-12-16 Compose a cycle diazole utilisable comme medicament

Country Status (15)

Country Link
JP (1) JPS5382779A (fr)
AT (1) AT368498B (fr)
AU (1) AU514523B2 (fr)
CH (1) CH639076A5 (fr)
DE (1) DE2755771A1 (fr)
DK (1) DK551777A (fr)
ES (1) ES465176A1 (fr)
FI (1) FI773812A (fr)
FR (1) FR2374309A1 (fr)
IL (1) IL53559A0 (fr)
NL (1) NL7713971A (fr)
NO (1) NO774348L (fr)
NZ (1) NZ185909A (fr)
PH (1) PH14398A (fr)
SE (1) SE7714373L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337262A (en) 1977-12-01 1982-06-29 Burroughs Wellcome Co. Hydantoin derivatives, pharmaceutical compounds and methods of use

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK543178A (da) * 1977-12-01 1979-06-02 Wellcome Found Thiodydantoinderivater
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (fr) * 1978-03-30 1979-10-17 Beecham Group Plc Déoxyhydantoines, leurs procédés de préparation et compositions pharmaceutiques les contenant
EP0006352A1 (fr) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoines et thiohydantoines, procédé pour leur préparation et compositions pharmaceutiques les contenant
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
US4294972A (en) * 1978-06-15 1981-10-13 Beecham Group Limited 1,2-Disubstituted oxo triazolidine
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
GB2050371A (en) * 1979-05-09 1981-01-07 Wellcome Found Optically active hydantoin derivatives and pharmaceutical formulations containing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2323193A1 (de) 1972-05-10 1973-11-22 Du Pont Pyrazolidinone
FR2258376A1 (en) 1974-01-21 1975-08-18 Aries Robert 10-Aza prostaglandins - for treatment of blood pressure and gastro-intestinal disorders and in prepn for confinement
GB1524818A (en) 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337262A (en) 1977-12-01 1982-06-29 Burroughs Wellcome Co. Hydantoin derivatives, pharmaceutical compounds and methods of use

Also Published As

Publication number Publication date
AU3161377A (en) 1979-06-21
SE7714373L (sv) 1978-06-19
NL7713971A (nl) 1978-06-20
CH639076A5 (en) 1983-10-31
NO774348L (no) 1978-06-20
AT368498B (de) 1982-10-11
ATA893777A (de) 1982-02-15
IL53559A0 (en) 1978-03-10
DK551777A (da) 1978-06-19
JPS5382779A (en) 1978-07-21
NZ185909A (en) 1980-11-14
FR2374309A1 (fr) 1978-07-13
ES465176A1 (es) 1979-01-01
DE2755771A1 (de) 1978-06-29
AU514523B2 (en) 1981-02-12
PH14398A (en) 1981-06-25
FI773812A (fi) 1978-06-19

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Legal Events

Date Code Title Description
ST Notification of lapse