FR2371923A1 - Sels de lysine et d'arginine de l'acide 7-((cyanomethylthio)-acetamido)-3-(2-(5-methyl-1, 3, 4-thiadiazolyl)-thiomethyl)-d3-cepheme-4-carboxylique et procede pour leur preparation - Google Patents
Sels de lysine et d'arginine de l'acide 7-((cyanomethylthio)-acetamido)-3-(2-(5-methyl-1, 3, 4-thiadiazolyl)-thiomethyl)-d3-cepheme-4-carboxylique et procede pour leur preparationInfo
- Publication number
- FR2371923A1 FR2371923A1 FR7636047A FR7636047A FR2371923A1 FR 2371923 A1 FR2371923 A1 FR 2371923A1 FR 7636047 A FR7636047 A FR 7636047A FR 7636047 A FR7636047 A FR 7636047A FR 2371923 A1 FR2371923 A1 FR 2371923A1
- Authority
- FR
- France
- Prior art keywords
- lysine
- carboxylic acid
- intramuscular injection
- arginine
- antibacterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000004472 Lysine Substances 0.000 title abstract 3
- 238000010255 intramuscular injection Methods 0.000 title abstract 2
- 239000007927 intramuscular injection Substances 0.000 title abstract 2
- UDTVQXNZIKQKOI-BAFYGKSASA-N (6r)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-4-carboxylic acid Chemical class C1=CC(C(=O)O)S[C@@H]2CC(=O)N21 UDTVQXNZIKQKOI-BAFYGKSASA-N 0.000 title 1
- 239000004475 Arginine Substances 0.000 title 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 4
- 235000019766 L-Lysine Nutrition 0.000 abstract 2
- 150000008545 L-lysines Chemical class 0.000 abstract 2
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- -1 L-arginino salts Chemical class 0.000 abstract 1
- 125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7636047A FR2371923A1 (fr) | 1976-11-30 | 1976-11-30 | Sels de lysine et d'arginine de l'acide 7-((cyanomethylthio)-acetamido)-3-(2-(5-methyl-1, 3, 4-thiadiazolyl)-thiomethyl)-d3-cepheme-4-carboxylique et procede pour leur preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7636047A FR2371923A1 (fr) | 1976-11-30 | 1976-11-30 | Sels de lysine et d'arginine de l'acide 7-((cyanomethylthio)-acetamido)-3-(2-(5-methyl-1, 3, 4-thiadiazolyl)-thiomethyl)-d3-cepheme-4-carboxylique et procede pour leur preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2371923A1 true FR2371923A1 (fr) | 1978-06-23 |
| FR2371923B1 FR2371923B1 (Direct) | 1979-03-23 |
Family
ID=9180468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7636047A Granted FR2371923A1 (fr) | 1976-11-30 | 1976-11-30 | Sels de lysine et d'arginine de l'acide 7-((cyanomethylthio)-acetamido)-3-(2-(5-methyl-1, 3, 4-thiadiazolyl)-thiomethyl)-d3-cepheme-4-carboxylique et procede pour leur preparation |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2371923A1 (Direct) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2190422A1 (Direct) * | 1972-06-30 | 1974-02-01 | Takeda Chemical Industries Ltd |
-
1976
- 1976-11-30 FR FR7636047A patent/FR2371923A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2190422A1 (Direct) * | 1972-06-30 | 1974-02-01 | Takeda Chemical Industries Ltd |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2371923B1 (Direct) | 1979-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |