FR2366311B1 - - Google Patents

Info

Publication number
FR2366311B1
FR2366311B1 FR7729043A FR7729043A FR2366311B1 FR 2366311 B1 FR2366311 B1 FR 2366311B1 FR 7729043 A FR7729043 A FR 7729043A FR 7729043 A FR7729043 A FR 7729043A FR 2366311 B1 FR2366311 B1 FR 2366311B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7729043A
Other languages
French (fr)
Other versions
FR2366311A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of FR2366311A1 publication Critical patent/FR2366311A1/en
Application granted granted Critical
Publication of FR2366311B1 publication Critical patent/FR2366311B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7729043A 1976-09-29 1977-09-27 PROCESS FOR THE PREPARATION OF POLYHALOGENIC STEROIDS USEFUL AS MEDICINAL PRODUCTS Granted FR2366311A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (en) 1976-09-29 1976-09-29

Publications (2)

Publication Number Publication Date
FR2366311A1 FR2366311A1 (en) 1978-04-28
FR2366311B1 true FR2366311B1 (en) 1982-12-03

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7729043A Granted FR2366311A1 (en) 1976-09-29 1977-09-27 PROCESS FOR THE PREPARATION OF POLYHALOGENIC STEROIDS USEFUL AS MEDICINAL PRODUCTS

Country Status (24)

Country Link
JP (1) JPS5356652A (en)
AT (3) AT363197B (en)
AU (1) AU514200B2 (en)
BE (1) BE859120A (en)
CA (1) CA1101410A (en)
CH (9) CH624967A5 (en)
CY (1) CY1178A (en)
DD (1) DD133150A5 (en)
DE (1) DE2743069C2 (en)
DK (1) DK146017C (en)
ES (1) ES462763A1 (en)
FR (1) FR2366311A1 (en)
GB (1) GB1563638A (en)
HK (1) HK16683A (en)
HU (1) HU175218B (en)
IE (1) IE46047B1 (en)
IL (1) IL53012A (en)
KE (1) KE3258A (en)
LU (1) LU75903A1 (en)
MY (1) MY8400092A (en)
NL (1) NL7710089A (en)
SE (1) SE436751B (en)
SG (1) SG3383G (en)
ZA (1) ZA775800B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (en) * 1978-04-05 1991-11-18 Sibla Srl 3-ACETOXY-9BETA, 11BETA-EPOXY-PREGNA-1,3,5-TRIEN, PROCESS FOR THE PREPARATION THEREOF, AND PROCESS FOR THE PREPARATION OF 6-alpha-halogen-1,4-diene-3-ones.
DE3227312A1 (en) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen NEW 6.16 DIMETHYL CORTICOIDS, THEIR PRODUCTION AND USE
EP0523132A1 (en) * 1990-03-27 1993-01-20 Schering Corporation PROCESS FOR 9$g(a)-HYDROXY STEROID DEHYDRATION
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
CA2473471A1 (en) 2001-11-29 2003-06-12 Taro Pharmaceuticals U.S.A., Inc. Method for the preparation of 6-alpha-fluoro corticosteroids
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
AU2016279801B2 (en) 2015-06-18 2021-09-09 Valeant Pharmaceuticals North America Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Also Published As

Publication number Publication date
AT363197B (en) 1981-07-10
BE859120A (en) 1978-03-28
CH632521A5 (en) 1982-10-15
ZA775800B (en) 1978-08-30
IE46047L (en) 1978-03-29
FR2366311A1 (en) 1978-04-28
CA1101410A (en) 1981-05-19
DK146017C (en) 1983-10-24
JPS5356652A (en) 1978-05-23
CH625809A5 (en) 1981-10-15
CY1178A (en) 1983-06-10
DK146017B (en) 1983-05-24
GB1563638A (en) 1980-03-26
HU175218B (en) 1980-06-28
AU2914877A (en) 1979-04-05
DE2743069C2 (en) 1987-03-05
IL53012A (en) 1982-05-31
ES462763A1 (en) 1978-05-16
HK16683A (en) 1983-05-27
AT363203B (en) 1981-07-27
NL7710089A (en) 1978-03-31
IE46047B1 (en) 1983-02-09
SG3383G (en) 1983-09-09
AT363202B (en) 1981-07-27
CH632279A5 (en) 1982-09-30
CH625808A5 (en) 1981-10-15
ATA691077A (en) 1980-12-15
CH631999A5 (en) 1982-09-15
CH624967A5 (en) 1981-08-31
SE7706673L (en) 1978-03-30
ATA151379A (en) 1980-12-15
IL53012A0 (en) 1977-11-30
DE2743069A1 (en) 1978-03-30
JPS6214557B2 (en) 1987-04-02
ATA151279A (en) 1980-12-15
CH631998A5 (en) 1982-09-15
KE3258A (en) 1983-03-04
SE436751B (en) 1985-01-21
LU75903A1 (en) 1978-05-16
MY8400092A (en) 1984-12-31
CH632000A5 (en) 1982-09-15
DD133150A5 (en) 1978-12-13
DK256977A (en) 1978-03-30
AU514200B2 (en) 1981-01-29
CH625810A5 (en) 1981-10-15

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Legal Events

Date Code Title Description
TP Transmission of property