FR2366293A1 - Nouvelles lactones utiles dans la synthese du thromboxane b2 - Google Patents
Nouvelles lactones utiles dans la synthese du thromboxane b2Info
- Publication number
- FR2366293A1 FR2366293A1 FR7735045A FR7735045A FR2366293A1 FR 2366293 A1 FR2366293 A1 FR 2366293A1 FR 7735045 A FR7735045 A FR 7735045A FR 7735045 A FR7735045 A FR 7735045A FR 2366293 A1 FR2366293 A1 FR 2366293A1
- Authority
- FR
- France
- Prior art keywords
- thromboxane
- synthesis
- lactons
- new useful
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- XNRNNGPBEPRNAR-UHFFFAOYSA-N Thromboxane B2 Natural products CCCCCC(O)C=CC1OC(O)CC(O)C1CC=CCCCC(O)=O XNRNNGPBEPRNAR-UHFFFAOYSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- XNRNNGPBEPRNAR-JQBLCGNGSA-N thromboxane B2 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1OC(O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O XNRNNGPBEPRNAR-JQBLCGNGSA-N 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Abstract
L'invention concerne de nouvelles lactones utiles comme intermédiaires pour la synthèse du thromboxane B2 .
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/676,893 US4048194A (en) | 1976-04-14 | 1976-04-14 | 6α-Methoxy-4α-hydroxy-2β-hydroxymethyl-3.alpha.-tetrahydropyranacetic acid 4α γ-lactone ethers and acylates |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2366293A1 true FR2366293A1 (fr) | 1978-04-28 |
FR2366293B1 FR2366293B1 (fr) | 1981-12-24 |
Family
ID=24716462
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7711304A Granted FR2435474A1 (fr) | 1976-04-14 | 1977-04-14 | Nouveaux composes utiles dans la synthese du thromboxane b2 |
FR7735045A Granted FR2366293A1 (fr) | 1976-04-14 | 1977-11-22 | Nouvelles lactones utiles dans la synthese du thromboxane b2 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7711304A Granted FR2435474A1 (fr) | 1976-04-14 | 1977-04-14 | Nouveaux composes utiles dans la synthese du thromboxane b2 |
Country Status (5)
Country | Link |
---|---|
US (8) | US4048194A (fr) |
JP (1) | JPS537664A (fr) |
DE (1) | DE2715921A1 (fr) |
FR (2) | FR2435474A1 (fr) |
GB (2) | GB1534991A (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4100176A (en) * | 1976-04-14 | 1978-07-11 | The Upjohn Company | 4,5-Didehydro-6-hydroxy-2β-arylmethoxymethyl-4α-tetrahydropyranacetic acids |
US4100178A (en) * | 1976-04-14 | 1978-07-11 | The Upjohn Company | 4,5-Didehydro-6-methoxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters |
US4083854A (en) * | 1976-04-14 | 1978-04-11 | The Upjohn Company | 4,5-Didehydro-6-oxo-2-aryl-methoxymethyl-3α-tetrahydropyranacetic acids |
US4100177A (en) * | 1976-04-14 | 1978-07-11 | The Upjohn Company | 4,5-Didehydro-6-hydroxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters |
US20060116207A1 (en) * | 2004-11-29 | 2006-06-01 | Barona Tribal Gaming Authority | Electronic gaming system |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3997570A (en) * | 1971-08-05 | 1976-12-14 | Chevron Research Company | Alkenyl halolactone esters |
US3971826A (en) * | 1972-07-13 | 1976-07-27 | Pfizer Inc. | 15-Substituted-ω-pentanorprostaglandins |
US4001286A (en) * | 1974-01-07 | 1977-01-04 | The Upjohn Company | Phenyl-substituted prostaglandin-β-type anologs |
GB1532551A (en) * | 1975-01-16 | 1978-11-15 | Chembro Holdings Pty Ltd | Furo(3,4-6)furone derivatives and their preparation |
US4052552A (en) * | 1976-08-20 | 1977-10-04 | The Upjohn Company | Thromboxane b analogs |
-
1976
- 1976-04-14 US US05/676,893 patent/US4048194A/en not_active Expired - Lifetime
-
1977
- 1977-04-09 DE DE19772715921 patent/DE2715921A1/de not_active Withdrawn
- 1977-04-14 GB GB39565/77A patent/GB1534991A/en not_active Expired
- 1977-04-14 GB GB15554/77A patent/GB1534986A/en not_active Expired
- 1977-04-14 FR FR7711304A patent/FR2435474A1/fr active Granted
- 1977-04-14 JP JP4213677A patent/JPS537664A/ja active Pending
- 1977-05-12 US US05/796,089 patent/US4102899A/en not_active Expired - Lifetime
- 1977-05-12 US US05/796,088 patent/US4085120A/en not_active Expired - Lifetime
- 1977-05-12 US US05/796,097 patent/US4143053A/en not_active Expired - Lifetime
- 1977-05-12 US US05/796,101 patent/US4086247A/en not_active Expired - Lifetime
- 1977-05-12 US US05/796,090 patent/US4120872A/en not_active Expired - Lifetime
- 1977-05-12 US US05/796,096 patent/US4102900A/en not_active Expired - Lifetime
- 1977-05-12 US US05/796,098 patent/US4097493A/en not_active Expired - Lifetime
- 1977-11-22 FR FR7735045A patent/FR2366293A1/fr active Granted
Non-Patent Citations (1)
Title |
---|
EXBK/76 * |
Also Published As
Publication number | Publication date |
---|---|
US4143053A (en) | 1979-03-06 |
US4048194A (en) | 1977-09-13 |
US4102899A (en) | 1978-07-25 |
FR2435474B1 (fr) | 1982-08-06 |
DE2715921A1 (de) | 1977-10-27 |
FR2366293B1 (fr) | 1981-12-24 |
US4085120A (en) | 1978-04-18 |
FR2435474A1 (fr) | 1980-04-04 |
GB1534991A (en) | 1978-12-06 |
GB1534986A (en) | 1978-12-06 |
US4097493A (en) | 1978-06-27 |
JPS537664A (en) | 1978-01-24 |
US4102900A (en) | 1978-07-25 |
US4120872A (en) | 1978-10-17 |
US4086247A (en) | 1978-04-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |