FR2364912A1 - Nouvelles 11-deoxy-11-oxaprostaglandines - Google Patents

Nouvelles 11-deoxy-11-oxaprostaglandines

Info

Publication number
FR2364912A1
FR2364912A1 FR7727747A FR7727747A FR2364912A1 FR 2364912 A1 FR2364912 A1 FR 2364912A1 FR 7727747 A FR7727747 A FR 7727747A FR 7727747 A FR7727747 A FR 7727747A FR 2364912 A1 FR2364912 A1 FR 2364912A1
Authority
FR
France
Prior art keywords
deoxy
oxaprostaglandines
news
new
prostaglandins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7727747A
Other languages
English (en)
Other versions
FR2364912B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2364912A1 publication Critical patent/FR2364912A1/fr
Application granted granted Critical
Publication of FR2364912B1 publication Critical patent/FR2364912B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Manipulator (AREA)

Abstract

Nouvelles 11-déoxy-11 -oxa-oméga-tétranor-prostaglandines de la série E portant sur l'atome C-16 un groupe phényle, phényle substitué, phénoxy ou phénoxy substitué, et leurs énantiomorphes. Les nouveaux composés de l'invention appartiennent à la classe des composés connus appelés prostaglandines. Ces nouveaux composés sont doués de propriétés pharmacologiques ; par exemple, certains d'entre eux abaissent la pression sanguine des mammifères, et peuvent être utilisés notamment en médecine humaine.
FR7727747A 1976-09-15 1977-09-14 Nouvelles 11-deoxy-11-oxaprostaglandines Granted FR2364912A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72360476A 1976-09-15 1976-09-15

Publications (2)

Publication Number Publication Date
FR2364912A1 true FR2364912A1 (fr) 1978-04-14
FR2364912B1 FR2364912B1 (fr) 1980-10-03

Family

ID=24906946

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7727747A Granted FR2364912A1 (fr) 1976-09-15 1977-09-14 Nouvelles 11-deoxy-11-oxaprostaglandines

Country Status (9)

Country Link
JP (1) JPS5337653A (fr)
BE (1) BE858682A (fr)
DE (1) DE2739277C2 (fr)
DK (1) DK408377A (fr)
FR (1) FR2364912A1 (fr)
GB (1) GB1539364A (fr)
IE (1) IE45773B1 (fr)
LU (1) LU78116A1 (fr)
NL (1) NL169739C (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337254A (en) 1977-08-23 1982-06-29 Burroughs Wellcome Co. Pharmaceutical compositions
JPS5915198A (ja) * 1982-07-15 1984-01-26 石川島播磨重工業株式会社 シ−ルド掘進機
JPS5927846U (ja) * 1982-08-13 1984-02-21 日本ワグナ−・スプレ−テツク株式会社 空圧制御式スプレ−ガン
JPS59210190A (ja) * 1983-05-11 1984-11-28 大和技建株式会社 圧気シ−ルド推進工法
JPS60112414U (ja) * 1984-01-06 1985-07-30 大阪機工株式会社 液体充填用紙製容器の注出栓
JPH041058Y2 (fr) * 1985-09-30 1992-01-14
JPH041056Y2 (fr) * 1985-09-30 1992-01-14
US5814660A (en) * 1995-12-22 1998-09-29 Alcon Laboratories, Inc. 9-oxa prostaglandin analogs as ocular hypotensives
DE69633136T2 (de) * 1995-12-22 2005-09-01 Alcon Laboratories, Inc., Fort Worth Substituierte tetrahydrofuran-analoge von prostaglandinen als augendrucksenkende mittel
US5866602A (en) * 1995-12-22 1999-02-02 Alcon Laboratories, Inc. Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives

Also Published As

Publication number Publication date
DK408377A (da) 1978-03-16
IE45773B1 (en) 1982-11-17
DE2739277C2 (de) 1982-06-09
NL169739B (nl) 1982-03-16
DE2739277A1 (de) 1978-03-16
LU78116A1 (fr) 1979-05-23
BE858682A (fr) 1978-03-14
JPS5755719B2 (fr) 1982-11-25
FR2364912B1 (fr) 1980-10-03
IE45773L (en) 1978-03-15
GB1539364A (en) 1979-01-31
NL169739C (nl) 1982-08-16
JPS5337653A (en) 1978-04-06
NL7710065A (nl) 1978-03-17

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Legal Events

Date Code Title Description
ST Notification of lapse