FR2357529A1 - NEW ACID ADDITIONAL SALTS OF D - (+) - 1 - (3-HYDROXYPHENYL) - 2 - AMINOPROPANE, USEFUL IN PARTICULAR AS SYMPATHOMIMETICS, AND THEIR PREPARATION PROCESS - Google Patents

NEW ACID ADDITIONAL SALTS OF D - (+) - 1 - (3-HYDROXYPHENYL) - 2 - AMINOPROPANE, USEFUL IN PARTICULAR AS SYMPATHOMIMETICS, AND THEIR PREPARATION PROCESS

Info

Publication number
FR2357529A1
FR2357529A1 FR7710639A FR7710639A FR2357529A1 FR 2357529 A1 FR2357529 A1 FR 2357529A1 FR 7710639 A FR7710639 A FR 7710639A FR 7710639 A FR7710639 A FR 7710639A FR 2357529 A1 FR2357529 A1 FR 2357529A1
Authority
FR
France
Prior art keywords
sympathomimetics
hydroxyphenyl
aminopropane
useful
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7710639A
Other languages
French (fr)
Other versions
FR2357529B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HELOPHARM PETRIK CO KG
Original Assignee
HELOPHARM PETRIK CO KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HELOPHARM PETRIK CO KG filed Critical HELOPHARM PETRIK CO KG
Publication of FR2357529A1 publication Critical patent/FR2357529A1/en
Application granted granted Critical
Publication of FR2357529B1 publication Critical patent/FR2357529B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • A—HUMAN NECESSITIES
    • A63—SPORTS; GAMES; AMUSEMENTS
    • A63B—APPARATUS FOR PHYSICAL TRAINING, GYMNASTICS, SWIMMING, CLIMBING, OR FENCING; BALL GAMES; TRAINING EQUIPMENT
    • A63B22/00—Exercising apparatus specially adapted for conditioning the cardio-vascular system, for training agility or co-ordination of movements
    • A63B22/0025—Particular aspects relating to the orientation of movement paths of the limbs relative to the body; Relative relationship between the movements of the limbs
    • A63B2022/0033—Lower limbs performing together the same movement, e.g. on a single support element

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne de nouvelles formes du D(+)-1-(3-hydroxyphényl)-2-aminorpopane qui consistent en sels d'addition d'acides physiologiquement acceptable, notamment le bitartrate. On peut administrer les composés comme antihypotoniques et sympathomimétiques en tablettes, capsules, dragees, sirops, solutions, suspensions et gouttes et suppositoires, la dose unitaire étant de 30 à 50 mg pour l'administration intraveineuse et de 10 à 120 mg pour l'administration orale.The invention relates to novel forms of D (+) - 1- (3-hydroxyphenyl) -2-aminorpopane which consist of physiologically acceptable acid addition salts, in particular bitartrate. The compounds can be administered as antihypotonics and sympathomimetics in tablets, capsules, drages, syrups, solutions, suspensions and drops and suppositories, the unit dose being 30 to 50 mg for intravenous administration and 10 to 120 mg for administration. oral.

FR7710639A 1976-07-09 1977-04-07 NEW ACID ADDITIONAL SALTS OF D - (+) - 1 - (3-HYDROXYPHENYL) - 2 - AMINOPROPANE, USEFUL IN PARTICULAR AS SYMPATHOMIMETICS, AND THEIR PREPARATION PROCESS Granted FR2357529A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT504676A AT343625B (en) 1976-07-09 1976-07-09 METHOD FOR PRODUCING NEW ACID ADDITION SALTS OF D - (+) - 1- (M-HYDROXYPHENYL) -2-AMINOPROPANE

Publications (2)

Publication Number Publication Date
FR2357529A1 true FR2357529A1 (en) 1978-02-03
FR2357529B1 FR2357529B1 (en) 1979-03-02

Family

ID=3571321

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7710639A Granted FR2357529A1 (en) 1976-07-09 1977-04-07 NEW ACID ADDITIONAL SALTS OF D - (+) - 1 - (3-HYDROXYPHENYL) - 2 - AMINOPROPANE, USEFUL IN PARTICULAR AS SYMPATHOMIMETICS, AND THEIR PREPARATION PROCESS

Country Status (16)

Country Link
JP (1) JPS539727A (en)
AR (1) AR216467A1 (en)
AT (1) AT343625B (en)
BE (1) BE853332A (en)
CH (1) CH629732A5 (en)
DE (1) DE2712860C3 (en)
DK (1) DK159203C (en)
ES (1) ES457992A1 (en)
FR (1) FR2357529A1 (en)
GB (1) GB1527479A (en)
GR (1) GR69605B (en)
NL (1) NL176744C (en)
PT (1) PT66752B (en)
SE (1) SE440902B (en)
SU (1) SU973018A3 (en)
ZA (1) ZA771767B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209788C2 (en) * 1982-03-15 1984-10-04 Rolf 1000 Berlin Sachse Process for the preparation of 1- (3-hydroxyphenyl) -2-aminopropane
DK600285D0 (en) * 1985-12-20 1985-12-20 Jens Erik Sattrup PROCEDURE FOR MANUFACTURING A DEEP PRESSURE CYLINDER

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB396951A (en) * 1931-09-19 1933-08-17 Ig Farbenindustrie Ag Manufacture of optically active 1-monohydroxy-phenyl-2-aminopropanols(1)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5013784A (en) * 1973-06-08 1975-02-13

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB396951A (en) * 1931-09-19 1933-08-17 Ig Farbenindustrie Ag Manufacture of optically active 1-monohydroxy-phenyl-2-aminopropanols(1)

Also Published As

Publication number Publication date
ATA504676A (en) 1977-10-15
AR216467A1 (en) 1979-12-28
CH629732A5 (en) 1982-05-14
DE2712860C3 (en) 1981-04-02
NL7706510A (en) 1978-01-11
SE440902B (en) 1985-08-26
SE7702469L (en) 1978-01-10
JPS539727A (en) 1978-01-28
NL176744C (en) 1985-06-03
GB1527479A (en) 1978-10-04
DK159203B (en) 1990-09-17
ES457992A1 (en) 1978-07-16
JPH0329782B2 (en) 1991-04-25
AT343625B (en) 1978-06-12
DE2712860A1 (en) 1978-01-12
PT66752B (en) 1978-11-27
DK159203C (en) 1991-02-11
SU973018A3 (en) 1982-11-07
DK127277A (en) 1978-01-10
ZA771767B (en) 1978-03-29
DE2712860B2 (en) 1980-07-10
PT66752A (en) 1977-07-01
GR69605B (en) 1982-07-05
FR2357529B1 (en) 1979-03-02
BE853332A (en) 1977-08-01

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