GB1527479A - Acid addition salts of d-(+)-1-(3-hydroxyphenyl)-2-aminopropane and their manufacture and use - Google Patents

Acid addition salts of d-(+)-1-(3-hydroxyphenyl)-2-aminopropane and their manufacture and use

Info

Publication number
GB1527479A
GB1527479A GB23228/77A GB2322877A GB1527479A GB 1527479 A GB1527479 A GB 1527479A GB 23228/77 A GB23228/77 A GB 23228/77A GB 2322877 A GB2322877 A GB 2322877A GB 1527479 A GB1527479 A GB 1527479A
Authority
GB
United Kingdom
Prior art keywords
aminopropane
hydroxyphenyl
acid addition
addition salts
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB23228/77A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HELOPHARM PETRIK CO KG
Original Assignee
HELOPHARM PETRIK CO KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HELOPHARM PETRIK CO KG filed Critical HELOPHARM PETRIK CO KG
Publication of GB1527479A publication Critical patent/GB1527479A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • A—HUMAN NECESSITIES
    • A63—SPORTS; GAMES; AMUSEMENTS
    • A63B—APPARATUS FOR PHYSICAL TRAINING, GYMNASTICS, SWIMMING, CLIMBING, OR FENCING; BALL GAMES; TRAINING EQUIPMENT
    • A63B22/00—Exercising apparatus specially adapted for conditioning the cardio-vascular system, for training agility or co-ordination of movements
    • A63B22/0025—Particular aspects relating to the orientation of movement paths of the limbs relative to the body; Relative relationship between the movements of the limbs
    • A63B2022/0033—Lower limbs performing together the same movement, e.g. on a single support element

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Physiologically tolerated acid addition salts of D-(+)-1-(3-hydroxyphenyl)-2-aminopropane with optically active acids are prepared. These salts are obtained by resolving racemic 1-(3-hydroxyphenyl)-2-aminopropane by the action of an acid with the L configuration. The salts can be used for the treatment of hypotensive circulatory states.
GB23228/77A 1976-07-09 1977-06-01 Acid addition salts of d-(+)-1-(3-hydroxyphenyl)-2-aminopropane and their manufacture and use Expired GB1527479A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT504676A AT343625B (en) 1976-07-09 1976-07-09 METHOD FOR PRODUCING NEW ACID ADDITION SALTS OF D - (+) - 1- (M-HYDROXYPHENYL) -2-AMINOPROPANE

Publications (1)

Publication Number Publication Date
GB1527479A true GB1527479A (en) 1978-10-04

Family

ID=3571321

Family Applications (1)

Application Number Title Priority Date Filing Date
GB23228/77A Expired GB1527479A (en) 1976-07-09 1977-06-01 Acid addition salts of d-(+)-1-(3-hydroxyphenyl)-2-aminopropane and their manufacture and use

Country Status (16)

Country Link
JP (1) JPS539727A (en)
AR (1) AR216467A1 (en)
AT (1) AT343625B (en)
BE (1) BE853332A (en)
CH (1) CH629732A5 (en)
DE (1) DE2712860C3 (en)
DK (1) DK159203C (en)
ES (1) ES457992A1 (en)
FR (1) FR2357529A1 (en)
GB (1) GB1527479A (en)
GR (1) GR69605B (en)
NL (1) NL176744C (en)
PT (1) PT66752B (en)
SE (1) SE440902B (en)
SU (1) SU973018A3 (en)
ZA (1) ZA771767B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209788C2 (en) * 1982-03-15 1984-10-04 Rolf 1000 Berlin Sachse Process for the preparation of 1- (3-hydroxyphenyl) -2-aminopropane
DK600285D0 (en) * 1985-12-20 1985-12-20 Jens Erik Sattrup PROCEDURE FOR MANUFACTURING A DEEP PRESSURE CYLINDER

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB396951A (en) * 1931-09-19 1933-08-17 Ig Farbenindustrie Ag Manufacture of optically active 1-monohydroxy-phenyl-2-aminopropanols(1)
JPS5013784A (en) * 1973-06-08 1975-02-13

Also Published As

Publication number Publication date
DE2712860A1 (en) 1978-01-12
SE7702469L (en) 1978-01-10
DK127277A (en) 1978-01-10
PT66752A (en) 1977-07-01
ATA504676A (en) 1977-10-15
FR2357529B1 (en) 1979-03-02
DK159203B (en) 1990-09-17
NL176744C (en) 1985-06-03
DE2712860B2 (en) 1980-07-10
ES457992A1 (en) 1978-07-16
PT66752B (en) 1978-11-27
AT343625B (en) 1978-06-12
JPS539727A (en) 1978-01-28
DE2712860C3 (en) 1981-04-02
FR2357529A1 (en) 1978-02-03
CH629732A5 (en) 1982-05-14
SU973018A3 (en) 1982-11-07
GR69605B (en) 1982-07-05
NL7706510A (en) 1978-01-11
DK159203C (en) 1991-02-11
ZA771767B (en) 1978-03-29
AR216467A1 (en) 1979-12-28
JPH0329782B2 (en) 1991-04-25
SE440902B (en) 1985-08-26
BE853332A (en) 1977-08-01

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950601