FR2351098A1 - Derives de l'isothiouree, leur procede de preparation et leur application therapeutique - Google Patents
Derives de l'isothiouree, leur procede de preparation et leur application therapeutiqueInfo
- Publication number
- FR2351098A1 FR2351098A1 FR7714766A FR7714766A FR2351098A1 FR 2351098 A1 FR2351098 A1 FR 2351098A1 FR 7714766 A FR7714766 A FR 7714766A FR 7714766 A FR7714766 A FR 7714766A FR 2351098 A1 FR2351098 A1 FR 2351098A1
- Authority
- FR
- France
- Prior art keywords
- preparation process
- therapeutic application
- isothiourea derivatives
- isothiourea
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000002541 isothioureas Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB19994/76A GB1592453A (en) | 1976-05-14 | 1976-05-14 | Aminoalkyl esters of carbarimidothioic acid and compositions having immunosuppressant activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2351098A1 true FR2351098A1 (fr) | 1977-12-09 |
| FR2351098B1 FR2351098B1 (enExample) | 1982-06-18 |
Family
ID=10138568
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7714766A Granted FR2351098A1 (fr) | 1976-05-14 | 1977-05-13 | Derives de l'isothiouree, leur procede de preparation et leur application therapeutique |
| FR8024334A Withdrawn FR2472935A1 (fr) | 1976-05-14 | 1980-11-17 | Compositions pharmaceutiques ayant un effet immunodepresseur a base de derives de l'isothiouree |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8024334A Withdrawn FR2472935A1 (fr) | 1976-05-14 | 1980-11-17 | Compositions pharmaceutiques ayant un effet immunodepresseur a base de derives de l'isothiouree |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4294854A (enExample) |
| JP (1) | JPS532420A (enExample) |
| AR (1) | AR218872A1 (enExample) |
| AT (1) | AT359521B (enExample) |
| AU (1) | AU509573B2 (enExample) |
| BE (1) | BE854553A (enExample) |
| CA (1) | CA1086758A (enExample) |
| CH (1) | CH620203A5 (enExample) |
| DE (1) | DE2721830A1 (enExample) |
| DK (1) | DK211277A (enExample) |
| ES (1) | ES458756A1 (enExample) |
| FI (1) | FI771400A7 (enExample) |
| FR (2) | FR2351098A1 (enExample) |
| GB (1) | GB1592453A (enExample) |
| HU (1) | HU174978B (enExample) |
| IE (1) | IE45144B1 (enExample) |
| IL (1) | IL52011A (enExample) |
| LU (1) | LU77332A1 (enExample) |
| NL (1) | NL7705331A (enExample) |
| NO (1) | NO771697L (enExample) |
| PT (1) | PT66509B (enExample) |
| SE (1) | SE7705658L (enExample) |
| ZA (1) | ZA772612B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0672244B2 (ja) * | 1984-12-12 | 1994-09-14 | 三菱マテリアル株式会社 | 貴金属造粒装置 |
| JPH08511266A (ja) * | 1993-06-07 | 1996-11-26 | アメリカ合衆国 | Ｍｈｃクラス▲ｉ▼抑制剤の自己免疫疾患及び移植拒絶治療への使用 |
| WO1996006076A1 (en) * | 1994-08-18 | 1996-02-29 | Chugai Seiyaku Kabushiki Kaisha | Amino acid derivative having nitrogen monoxide synthetase inhibitor activity |
| US7645873B2 (en) * | 2003-03-20 | 2010-01-12 | The Scripps Research Institute | 6″-amino-6″-deoxygalactosylceramides |
| EP2058011A1 (en) * | 2007-11-07 | 2009-05-13 | Wittycell | Nkt cell activating gycolipids covalently bound antigens and/or drug |
| CN102215864A (zh) * | 2008-10-08 | 2011-10-12 | 威蒂赛尔公司 | 用于抗流感的疫苗组合物 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2813102A (en) * | 1956-04-10 | 1957-11-12 | American Home Prod | 2-(di-lower alkylaminoethylmercapto)-imidazolines and their acid addition salts and preparation thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2648710A (en) * | 1950-09-22 | 1953-08-11 | Hoffmann La Roche | Bis-quaternary salts of 1:10-bis-(dialkylamino)-5:6-dithia-decane |
| US4152453A (en) * | 1975-12-01 | 1979-05-01 | Smith Kline & French Laboratories Limited | Pharmacologically active compounds and compositions and methods of use |
-
1976
- 1976-05-14 GB GB19994/76A patent/GB1592453A/en not_active Expired
-
1977
- 1977-05-02 ZA ZA00772612A patent/ZA772612B/xx unknown
- 1977-05-03 FI FI771400A patent/FI771400A7/fi not_active Application Discontinuation
- 1977-05-04 IL IL52011A patent/IL52011A/xx unknown
- 1977-05-04 PT PT66509A patent/PT66509B/pt unknown
- 1977-05-04 AT AT318277A patent/AT359521B/de not_active IP Right Cessation
- 1977-05-10 IE IE947/77A patent/IE45144B1/en unknown
- 1977-05-11 JP JP5483077A patent/JPS532420A/ja active Pending
- 1977-05-11 CH CH589877A patent/CH620203A5/fr not_active IP Right Cessation
- 1977-05-11 AU AU25079/77A patent/AU509573B2/en not_active Expired
- 1977-05-12 BE BE177510A patent/BE854553A/xx not_active IP Right Cessation
- 1977-05-13 DE DE19772721830 patent/DE2721830A1/de not_active Withdrawn
- 1977-05-13 NL NL7705331A patent/NL7705331A/xx not_active Application Discontinuation
- 1977-05-13 DK DK211277A patent/DK211277A/da not_active Application Discontinuation
- 1977-05-13 LU LU77332A patent/LU77332A1/xx unknown
- 1977-05-13 AR AR267623A patent/AR218872A1/es active
- 1977-05-13 HU HU77SI1576A patent/HU174978B/hu unknown
- 1977-05-13 NO NO771697A patent/NO771697L/no unknown
- 1977-05-13 FR FR7714766A patent/FR2351098A1/fr active Granted
- 1977-05-13 ES ES458756A patent/ES458756A1/es not_active Expired
- 1977-05-13 CA CA278,412A patent/CA1086758A/en not_active Expired
- 1977-05-16 SE SE7705658A patent/SE7705658L/xx unknown
-
1979
- 1979-10-09 US US06/082,836 patent/US4294854A/en not_active Expired - Lifetime
-
1980
- 1980-11-17 FR FR8024334A patent/FR2472935A1/fr not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2813102A (en) * | 1956-04-10 | 1957-11-12 | American Home Prod | 2-(di-lower alkylaminoethylmercapto)-imidazolines and their acid addition salts and preparation thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| IE45144B1 (en) | 1982-06-30 |
| JPS532420A (en) | 1978-01-11 |
| SE7705658L (sv) | 1977-11-15 |
| AU509573B2 (en) | 1980-05-15 |
| ES458756A1 (es) | 1978-03-01 |
| BE854553A (fr) | 1977-11-14 |
| DK211277A (da) | 1977-11-15 |
| US4294854A (en) | 1981-10-13 |
| GB1592453A (en) | 1981-07-08 |
| DE2721830A1 (de) | 1977-11-24 |
| AU2507977A (en) | 1978-11-16 |
| AT359521B (de) | 1980-11-10 |
| HU174978B (hu) | 1980-04-28 |
| IE45144L (en) | 1977-11-14 |
| ATA318277A (de) | 1980-04-15 |
| IL52011A (en) | 1982-05-31 |
| AR218872A1 (es) | 1980-07-15 |
| FR2351098B1 (enExample) | 1982-06-18 |
| LU77332A1 (enExample) | 1977-08-29 |
| FI771400A7 (enExample) | 1977-11-15 |
| ZA772612B (en) | 1978-04-26 |
| NL7705331A (nl) | 1977-11-16 |
| PT66509A (en) | 1977-06-01 |
| PT66509B (en) | 1978-10-16 |
| NO771697L (no) | 1977-11-15 |
| CH620203A5 (enExample) | 1980-11-14 |
| CA1086758A (en) | 1980-09-30 |
| FR2472935A1 (fr) | 1981-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |