FR2350101A1 - Nouvelles guanidines cyclisees - Google Patents
Nouvelles guanidines cycliseesInfo
- Publication number
- FR2350101A1 FR2350101A1 FR7613681A FR7613681A FR2350101A1 FR 2350101 A1 FR2350101 A1 FR 2350101A1 FR 7613681 A FR7613681 A FR 7613681A FR 7613681 A FR7613681 A FR 7613681A FR 2350101 A1 FR2350101 A1 FR 2350101A1
- Authority
- FR
- France
- Prior art keywords
- antihypertensives
- piperidino
- dimethoxy
- alkylene
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 alkylene-diamino quinazolines Chemical class 0.000 title abstract 2
- 229940030600 antihypertensive agent Drugs 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 241000700159 Rattus Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7613681A FR2350101A1 (fr) | 1976-05-07 | 1976-05-07 | Nouvelles guanidines cyclisees |
| DK199277A DK140695C (da) | 1976-05-07 | 1977-05-05 | Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf |
| NO771610A NO771610L (no) | 1976-05-07 | 1977-05-06 | Fremgangsm}te for fremstilling av kinazolin-derivater |
| GB19223/77A GB1530768A (en) | 1976-05-07 | 1977-05-06 | 2-substituted-4-amino-6,7-dimethoxyquinazolines |
| IE921/77A IE45051B1 (en) | 1976-05-07 | 1977-05-06 | 2-substituted-4-amino-6,7-dimethoxy-quinazolines |
| SE7705310A SE432250B (sv) | 1976-05-07 | 1977-05-06 | Forfarande for framstellning av ett kinazolinderivat |
| PT66526A PT66526B (fr) | 1976-05-07 | 1977-05-06 | Procede de preparation de derives de quinazoline |
| AU24975/77A AU506410B2 (en) | 1976-05-07 | 1977-05-06 | Quinazoline derivatives |
| ES77458557A ES458557A1 (es) | 1976-05-07 | 1977-05-06 | Un procedimiento de preparacion de derivados de quinazolina. |
| BE177359A BE854363A (fr) | 1976-05-07 | 1977-05-06 | Derives de quinazoline |
| LU77283A LU77283A1 (OSRAM) | 1976-05-07 | 1977-05-06 | |
| FI771447A FI771447A7 (OSRAM) | 1976-05-07 | 1977-05-06 | |
| DE2720545A DE2720545C3 (de) | 1976-05-07 | 1977-05-06 | Derivate des 2,4-Diamino-6,7-dimethoxychinazolins, ihre Herstellung und pharmazeutische Mittel |
| CA277,884A CA1056831A (en) | 1976-05-07 | 1977-05-06 | Quinazoline derivatives |
| NLAANVRAGE7704979,A NL188527C (nl) | 1976-05-07 | 1977-05-06 | Werkwijze ter bereiding van een een dimethoxychinazolinederivaat bevattend geneesmiddel, gevormd geneesmiddel met bloeddrukverlagende werking en werkwijze ter bereiding van de werkzame stof. |
| CH570977A CH599193A5 (OSRAM) | 1976-05-07 | 1977-05-06 | |
| ZA00772728A ZA772728B (en) | 1976-05-07 | 1977-05-06 | Quinazoline derivatives |
| IL52041A IL52041A (en) | 1976-05-07 | 1977-05-06 | Quinazoline derivatives,their preparation and pharmaceutical compositions containing them |
| GR53393A GR63196B (en) | 1976-05-07 | 1977-05-06 | Preparation process of quinazoline derivatives |
| JP52052551A JPS6022714B2 (ja) | 1976-05-07 | 1977-05-07 | キナゾリン誘導体及びその製造法 |
| NZ184050A NZ184050A (en) | 1976-05-07 | 1977-05-09 | 2-substituted amino-4-amono-6,7-demethoxy-quinzaolines |
| US05/795,375 US4341893A (en) | 1976-05-07 | 1977-05-09 | Quinazoline derivatives |
| AT473479A AT357166B (de) | 1976-05-07 | 1979-07-06 | Verfahren zur herstellung von neuen china- zolinderivaten und ihren salzen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7613681A FR2350101A1 (fr) | 1976-05-07 | 1976-05-07 | Nouvelles guanidines cyclisees |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2350101A1 true FR2350101A1 (fr) | 1977-12-02 |
| FR2350101B1 FR2350101B1 (OSRAM) | 1979-10-05 |
Family
ID=9172812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7613681A Granted FR2350101A1 (fr) | 1976-05-07 | 1976-05-07 | Nouvelles guanidines cyclisees |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS6022714B2 (OSRAM) |
| BE (1) | BE854363A (OSRAM) |
| FR (1) | FR2350101A1 (OSRAM) |
| ZA (1) | ZA772728B (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5675006A (en) * | 1992-08-31 | 1997-10-07 | Brantford Chemicals Inc. | Methods of making ureas and guanidines, including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin, and bunazosin (exemplary of 2- substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2421888A1 (fr) * | 1978-02-06 | 1979-11-02 | Synthelabo | Amides d'alkylene-diamines et leur application en therapeutique |
| AU3578595A (en) * | 1994-11-25 | 1996-06-19 | Nippon Chemiphar Co. Ltd. | Quinazoline derivative |
| JP2020503377A (ja) * | 2016-12-13 | 2020-01-30 | ベータ セラピューティクス プロプライアタリー リミティド | ヘパラナーゼ阻害剤及びそれの使用 |
-
1976
- 1976-05-07 FR FR7613681A patent/FR2350101A1/fr active Granted
-
1977
- 1977-05-06 ZA ZA00772728A patent/ZA772728B/xx unknown
- 1977-05-06 BE BE177359A patent/BE854363A/xx not_active IP Right Cessation
- 1977-05-07 JP JP52052551A patent/JPS6022714B2/ja not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5675006A (en) * | 1992-08-31 | 1997-10-07 | Brantford Chemicals Inc. | Methods of making ureas and guanidines, including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin, and bunazosin (exemplary of 2- substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor |
| US6080860A (en) * | 1992-08-31 | 2000-06-27 | Brantford Chemicalss Inc. | Methods of making ureas and guanidines including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin and bunazosin (exemplary of 2-substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2350101B1 (OSRAM) | 1979-10-05 |
| JPS52139086A (en) | 1977-11-19 |
| JPS6022714B2 (ja) | 1985-06-03 |
| ZA772728B (en) | 1978-04-26 |
| BE854363A (fr) | 1977-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |