FR2347350A1 - Nouvelles 1-nitro-9-dialkylaminoisoalkylaminoacridines ou leurs sels utilisables en therapeutique et leur mode de production - Google Patents

Nouvelles 1-nitro-9-dialkylaminoisoalkylaminoacridines ou leurs sels utilisables en therapeutique et leur mode de production

Info

Publication number
FR2347350A1
FR2347350A1 FR7710426A FR7710426A FR2347350A1 FR 2347350 A1 FR2347350 A1 FR 2347350A1 FR 7710426 A FR7710426 A FR 7710426A FR 7710426 A FR7710426 A FR 7710426A FR 2347350 A1 FR2347350 A1 FR 2347350A1
Authority
FR
France
Prior art keywords
dialkylaminoisoalkylaminoacridins
nitro
salts
new
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7710426A
Other languages
English (en)
French (fr)
Other versions
FR2347350B1 (enExample
Inventor
Andrzej Ledochowski
Cecylia Kwasniewska-Rokicinska
Mieczyslaw Medon
Czeslaw Radzikowski
Lucyna Sawinska
Jerzy Gieldanowski
Barbara Wysocka-Skrzela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gdansk University of Technology
Original Assignee
Gdansk University of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gdansk University of Technology filed Critical Gdansk University of Technology
Publication of FR2347350A1 publication Critical patent/FR2347350A1/fr
Application granted granted Critical
Publication of FR2347350B1 publication Critical patent/FR2347350B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
FR7710426A 1976-04-06 1977-04-06 Nouvelles 1-nitro-9-dialkylaminoisoalkylaminoacridines ou leurs sels utilisables en therapeutique et leur mode de production Granted FR2347350A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL1976188528A PL101032B1 (pl) 1976-04-06 1976-04-06 Sposob otrzymywania 1-nitro-9-dwualkilo-aminoizoalkiloamiroakrydyn lub ich soli

Publications (2)

Publication Number Publication Date
FR2347350A1 true FR2347350A1 (fr) 1977-11-04
FR2347350B1 FR2347350B1 (enExample) 1980-02-01

Family

ID=19976296

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7710426A Granted FR2347350A1 (fr) 1976-04-06 1977-04-06 Nouvelles 1-nitro-9-dialkylaminoisoalkylaminoacridines ou leurs sels utilisables en therapeutique et leur mode de production

Country Status (12)

Country Link
US (1) US4150231A (enExample)
JP (1) JPS52151178A (enExample)
BE (1) BE852855A (enExample)
CH (1) CH634561A5 (enExample)
DE (1) DE2713103C2 (enExample)
FR (1) FR2347350A1 (enExample)
GB (1) GB1579588A (enExample)
HU (1) HU173105B (enExample)
NL (1) NL7703680A (enExample)
PL (1) PL101032B1 (enExample)
SE (1) SE435712B (enExample)
SU (2) SU683617A3 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0179383A3 (en) * 1984-10-25 1987-01-28 Hoechst-Roussel Pharmaceuticals Incorporated 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335244A (en) * 1979-11-30 1982-06-15 Bristol-Myers Company Monolactate salts of 4'-(9-acridinylamino)methanesulfon-m-anisidide
JPS56127370A (en) * 1980-02-15 1981-10-06 Mitsui Toatsu Chem Inc Novel piperazine compound, its preparation and utilization
PL126407B1 (en) * 1980-04-23 1983-07-30 Politechnika Gdanska Process for preparing 1-nitro-9-hydroxyalkylaminoacridines or their salts
HU186383B (en) * 1981-02-27 1985-07-29 Biogal Gyogyszergyar Process for producing new citostatic amni-acridie-alpha, beta-bracket-d-bracket closed, or aracket-l-bracket closed-n-glycoside derivatives and salts
US4575509A (en) * 1983-01-31 1986-03-11 Bristol-Myers Company Water-soluble formulations of m-AMSA with pyroglutamic acid
US4626540A (en) * 1983-11-08 1986-12-02 Warner-Lambert Company Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
WO2001060801A2 (en) * 2000-02-18 2001-08-23 New York Medical College 9-alkylamino-1-nitroacridine derivatives
US6589961B2 (en) 2000-02-18 2003-07-08 New York Medical College 9-alkylamino-1-nitroacridine derivatives
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
EP2427178B1 (en) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1962277A (en) * 1927-01-11 1934-06-12 Winthrop Chem Co Inc Basic nitroderivatives of 9-aminoacridines and process for preparing the same
DE1620473C3 (de) * 1964-05-25 1980-03-20 Starogardzkie Zaklady Farmaceutyczne Polfa Przedsiebiorstwo Panstwowe, Starogard Gdanski (Polen) Verfahren zur Herstellung von 1 -Nitro-9-(3'-dimethylaminopropylamino)-acridin-dihydrochlorid
US3897435A (en) * 1968-08-31 1975-07-29 Starogadzkie Zaklady Farmaceut N-oxides of 1 -nitro-9-dialkylaminoalkylamino/acridine
CH517096A (de) * 1968-08-31 1971-12-31 Starogardzkie Zakl Farma Verfahren zur Herstellung neuer, biologisch aktiver 1-Nitro-9-(dialkyl-aminoalkylamino)-akridin-N10-oxide

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0179383A3 (en) * 1984-10-25 1987-01-28 Hoechst-Roussel Pharmaceuticals Incorporated 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
BE852855A (fr) 1977-07-18
CH634561A5 (de) 1983-02-15
DE2713103C2 (de) 1982-02-04
PL101032B1 (pl) 1978-11-30
US4150231A (en) 1979-04-17
JPS52151178A (en) 1977-12-15
DE2713103A1 (de) 1977-10-13
HU173105B (hu) 1979-02-28
FR2347350B1 (enExample) 1980-02-01
SE7703979L (sv) 1977-10-07
SU682127A3 (ru) 1979-08-25
SE435712B (sv) 1984-10-15
JPS5527908B2 (enExample) 1980-07-24
GB1579588A (en) 1980-11-19
SU683617A3 (ru) 1979-08-30
NL7703680A (nl) 1977-10-10

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Legal Events

Date Code Title Description
ST Notification of lapse