FR2336126B1 - - Google Patents

Info

Publication number
FR2336126B1
FR2336126B1 FR7638482A FR7638482A FR2336126B1 FR 2336126 B1 FR2336126 B1 FR 2336126B1 FR 7638482 A FR7638482 A FR 7638482A FR 7638482 A FR7638482 A FR 7638482A FR 2336126 B1 FR2336126 B1 FR 2336126B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7638482A
Other languages
French (fr)
Other versions
FR2336126A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Publication of FR2336126A1 publication Critical patent/FR2336126A1/en
Application granted granted Critical
Publication of FR2336126B1 publication Critical patent/FR2336126B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12Radicals substituted by oxygen atoms
FR7638482A 1975-12-24 1976-12-21 PHENYLACETIC ACID ESTERS DERIVATIVES Granted FR2336126A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50156799A JPS5826744B2 (en) 1975-12-24 1975-12-24 Shinkinapropionsan Ester Yudou Tino Seizou

Publications (2)

Publication Number Publication Date
FR2336126A1 FR2336126A1 (en) 1977-07-22
FR2336126B1 true FR2336126B1 (en) 1979-03-09

Family

ID=15635562

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7638482A Granted FR2336126A1 (en) 1975-12-24 1976-12-21 PHENYLACETIC ACID ESTERS DERIVATIVES

Country Status (9)

Country Link
JP (1) JPS5826744B2 (en)
AU (1) AU507661B2 (en)
CA (1) CA1076134A (en)
CH (1) CH617919A5 (en)
DE (1) DE2658610C2 (en)
FR (1) FR2336126A1 (en)
GB (1) GB1573322A (en)
NL (1) NL180381C (en)
SE (1) SE433492B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5517358A (en) * 1978-07-24 1980-02-06 Teikoku Seiyaku Kk Butyl propionate derivative, its preparation, and antiphlogistic and analgesic comprising it
JPS54144336A (en) * 1978-07-24 1979-11-10 Teikoku Seiyaku Kk Propionic acid propylester derivative*its manufacture and antiiinflammatory and sedative agent containing it
JPS5587770A (en) * 1978-12-27 1980-07-02 Hisamitsu Pharmaceut Co Inc Preparation of 2-(p-isobutylphenyl)propionic acid 2-pyridinemethyl ester
JPS57203035A (en) * 1981-06-05 1982-12-13 Taisho Pharmaceut Co Ltd Carboxylic acid ester
DE3225290A1 (en) * 1982-07-07 1984-01-12 Merck Patent Gmbh RING CONNECTIONS
YU43408B (en) * 1985-04-26 1989-06-30 Lek Tovarna Farmacevtskih Process for preparation of 2-(4-isobuthylphenyl)-prophiohydroxamic acid
JPH0635378B2 (en) * 1985-06-27 1994-05-11 ポ−ラ化成工業株式会社 Cosmetics
ES2004447A6 (en) * 1987-07-06 1989-01-01 Sune Coma Nuria New 2-(P-isobutylphenyl)-propionic acid ester and process for the preparation thereof.
DE3811118C1 (en) * 1988-03-31 1989-10-12 Merckle Gmbh, 7902 Blaubeuren, De
IT1217589B (en) * 1988-05-13 1990-03-30 Pulitzer Italiana ANTI-INFLAMMATORY AGENT FOR THERAPY OF PROSTATIC HYPERTROPHY, ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
JPH0639449B2 (en) * 1989-04-10 1994-05-25 エーザイ株式会社 Polyprenyl compound, method for producing the same, and medicament containing the same
KR100198044B1 (en) 1991-05-13 1999-06-15 아이 에이 호틴 Pharmaceutical composition comprising ibuprofen salt
US6399618B1 (en) 1997-07-09 2002-06-04 Cardiome Pharma Corp Compositions and methods for modulating sexual activity
CN103948571A (en) * 2006-07-18 2014-07-30 天津昕晨泰飞尔医药科技有限公司 Water-soluble ibuprofen prodrug with high skin penetration rate and positive charge
AU2006347391B2 (en) * 2006-08-15 2013-03-07 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
PL2170826T3 (en) 2007-06-04 2022-09-05 Techfields Inc Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
EP2773378B1 (en) * 2011-10-31 2016-08-10 Larsen, Claus Selch Prodrugs of non-steroid anti-inflammatory agents (nsaids)
US9557087B2 (en) 2012-12-13 2017-01-31 Whirlpool Corporation Clear ice making apparatus having an oscillation frequency and angle
US9500398B2 (en) 2012-12-13 2016-11-22 Whirlpool Corporation Twist harvest ice geometry
US9470448B2 (en) 2012-12-13 2016-10-18 Whirlpool Corporation Apparatus to warm plastic side of mold
US9273891B2 (en) 2012-12-13 2016-03-01 Whirlpool Corporation Rotational ice maker
CN105461731B (en) * 2014-08-07 2017-05-24 富力 Phillygenin ibuprofen ester, preparation and applications thereof
EP3209953B1 (en) 2014-10-23 2020-03-25 Whirlpool Corporation Method and apparatus for increasing rate of ice production in an automatic ice maker
JP6153264B2 (en) * 2015-01-05 2017-06-28 テックフィールズ インコーポレイテッド NSAIA prodrug with very fast skin and membrane permeation rate and novel pharmaceutical use thereof
CN109134262A (en) * 2017-06-15 2019-01-04 北京蓝丹医药科技有限公司 A kind of loxoprofen derivative
CN109134261A (en) * 2017-06-15 2019-01-04 北京蓝丹医药科技有限公司 A kind of loxoprofen derivative
US10907874B2 (en) 2018-10-22 2021-02-02 Whirlpool Corporation Ice maker downspout

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents

Also Published As

Publication number Publication date
DE2658610A1 (en) 1977-07-07
JPS5278848A (en) 1977-07-02
FR2336126A1 (en) 1977-07-22
AU2087876A (en) 1978-06-29
CA1076134A (en) 1980-04-22
NL7614308A (en) 1977-06-28
SE7613651L (en) 1977-06-25
CH617919A5 (en) 1980-06-30
SE433492B (en) 1984-05-28
GB1573322A (en) 1980-08-20
NL180381C (en) 1987-02-16
DE2658610C2 (en) 1982-12-23
NL180381B (en) 1986-09-16
JPS5826744B2 (en) 1983-06-04
AU507661B2 (en) 1980-02-21

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