FR2336126B1 - - Google Patents
Info
- Publication number
- FR2336126B1 FR2336126B1 FR7638482A FR7638482A FR2336126B1 FR 2336126 B1 FR2336126 B1 FR 2336126B1 FR 7638482 A FR7638482 A FR 7638482A FR 7638482 A FR7638482 A FR 7638482A FR 2336126 B1 FR2336126 B1 FR 2336126B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50156799A JPS5826744B2 (en) | 1975-12-24 | 1975-12-24 | Shinkinapropionsan Ester Yudou Tino Seizou |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2336126A1 FR2336126A1 (en) | 1977-07-22 |
FR2336126B1 true FR2336126B1 (en) | 1979-03-09 |
Family
ID=15635562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7638482A Granted FR2336126A1 (en) | 1975-12-24 | 1976-12-21 | PHENYLACETIC ACID ESTERS DERIVATIVES |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS5826744B2 (en) |
AU (1) | AU507661B2 (en) |
CA (1) | CA1076134A (en) |
CH (1) | CH617919A5 (en) |
DE (1) | DE2658610C2 (en) |
FR (1) | FR2336126A1 (en) |
GB (1) | GB1573322A (en) |
NL (1) | NL180381C (en) |
SE (1) | SE433492B (en) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54144336A (en) * | 1978-07-24 | 1979-11-10 | Teikoku Seiyaku Kk | Propionic acid propylester derivative*its manufacture and antiiinflammatory and sedative agent containing it |
JPS5517358A (en) * | 1978-07-24 | 1980-02-06 | Teikoku Seiyaku Kk | Butyl propionate derivative, its preparation, and antiphlogistic and analgesic comprising it |
JPS5587770A (en) * | 1978-12-27 | 1980-07-02 | Hisamitsu Pharmaceut Co Inc | Preparation of 2-(p-isobutylphenyl)propionic acid 2-pyridinemethyl ester |
JPS57203035A (en) * | 1981-06-05 | 1982-12-13 | Taisho Pharmaceut Co Ltd | Carboxylic acid ester |
DE3225290A1 (en) * | 1982-07-07 | 1984-01-12 | Merck Patent Gmbh | RING CONNECTIONS |
YU43408B (en) * | 1985-04-26 | 1989-06-30 | Lek Tovarna Farmacevtskih | Process for preparation of 2-(4-isobuthylphenyl)-prophiohydroxamic acid |
JPH0635378B2 (en) * | 1985-06-27 | 1994-05-11 | ポ−ラ化成工業株式会社 | Cosmetics |
ES2004447A6 (en) * | 1987-07-06 | 1989-01-01 | Sune Coma Nuria | New 2-(P-isobutylphenyl)-propionic acid ester and process for the preparation thereof. |
DE3811118C1 (en) * | 1988-03-31 | 1989-10-12 | Merckle Gmbh, 7902 Blaubeuren, De | |
IT1217589B (en) * | 1988-05-13 | 1990-03-30 | Pulitzer Italiana | ANTI-INFLAMMATORY AGENT FOR THERAPY OF PROSTATIC HYPERTROPHY, ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS |
JPH0639449B2 (en) * | 1989-04-10 | 1994-05-25 | エーザイ株式会社 | Polyprenyl compound, method for producing the same, and medicament containing the same |
WO1992020334A1 (en) | 1991-05-13 | 1992-11-26 | The Boots Company Plc | Pharmaceutical composition comprising ibuprofen salt |
US6399618B1 (en) * | 1997-07-09 | 2002-06-04 | Cardiome Pharma Corp | Compositions and methods for modulating sexual activity |
CN103948571A (en) * | 2006-07-18 | 2014-07-30 | 天津昕晨泰飞尔医药科技有限公司 | Water-soluble ibuprofen prodrug with high skin penetration rate and positive charge |
JP5424880B2 (en) * | 2006-08-15 | 2014-02-26 | テックフィールズ バイオケム カンパニー リミテッド | Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin permeability |
PL2170826T3 (en) | 2007-06-04 | 2022-09-05 | Techfields Inc | Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses |
EP2773378B1 (en) | 2011-10-31 | 2016-08-10 | Larsen, Claus Selch | Prodrugs of non-steroid anti-inflammatory agents (nsaids) |
US9500398B2 (en) | 2012-12-13 | 2016-11-22 | Whirlpool Corporation | Twist harvest ice geometry |
US9470448B2 (en) | 2012-12-13 | 2016-10-18 | Whirlpool Corporation | Apparatus to warm plastic side of mold |
US9557087B2 (en) | 2012-12-13 | 2017-01-31 | Whirlpool Corporation | Clear ice making apparatus having an oscillation frequency and angle |
US9759472B2 (en) | 2012-12-13 | 2017-09-12 | Whirlpool Corporation | Clear ice maker with warm air flow |
CN105461731B (en) * | 2014-08-07 | 2017-05-24 | 富力 | Phillygenin ibuprofen ester, preparation and applications thereof |
WO2016065269A2 (en) | 2014-10-23 | 2016-04-28 | Whirlpool Corporation | Method and apparatus for increasing rate of ice production in an automatic ice maker |
JP6153264B2 (en) * | 2015-01-05 | 2017-06-28 | テックフィールズ インコーポレイテッド | NSAIA prodrug with very fast skin and membrane permeation rate and novel pharmaceutical use thereof |
CN109134261A (en) * | 2017-06-15 | 2019-01-04 | 北京蓝丹医药科技有限公司 | A kind of loxoprofen derivative |
CN109134262A (en) * | 2017-06-15 | 2019-01-04 | 北京蓝丹医药科技有限公司 | A kind of loxoprofen derivative |
US10907874B2 (en) | 2018-10-22 | 2021-02-02 | Whirlpool Corporation | Ice maker downspout |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
-
1975
- 1975-12-24 JP JP50156799A patent/JPS5826744B2/en not_active Expired
-
1976
- 1976-12-06 SE SE7613651A patent/SE433492B/en not_active IP Right Cessation
- 1976-12-13 CA CA267,690A patent/CA1076134A/en not_active Expired
- 1976-12-21 FR FR7638482A patent/FR2336126A1/en active Granted
- 1976-12-21 CH CH1607276A patent/CH617919A5/en not_active IP Right Cessation
- 1976-12-23 AU AU20878/76A patent/AU507661B2/en not_active Expired
- 1976-12-23 NL NLAANVRAGE7614308,A patent/NL180381C/en not_active IP Right Cessation
- 1976-12-23 DE DE2658610A patent/DE2658610C2/en not_active Expired
- 1976-12-24 GB GB51350/76A patent/GB1573322A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2658610C2 (en) | 1982-12-23 |
JPS5826744B2 (en) | 1983-06-04 |
NL180381C (en) | 1987-02-16 |
AU507661B2 (en) | 1980-02-21 |
DE2658610A1 (en) | 1977-07-07 |
GB1573322A (en) | 1980-08-20 |
SE433492B (en) | 1984-05-28 |
CH617919A5 (en) | 1980-06-30 |
FR2336126A1 (en) | 1977-07-22 |
NL180381B (en) | 1986-09-16 |
AU2087876A (en) | 1978-06-29 |
NL7614308A (en) | 1977-06-28 |
CA1076134A (en) | 1980-04-22 |
JPS5278848A (en) | 1977-07-02 |
SE7613651L (en) | 1977-06-25 |