AU507661B2 - Phenylacetic acid ester derivatives - Google Patents

Phenylacetic acid ester derivatives

Info

Publication number
AU507661B2
AU507661B2 AU20878/76A AU2087876A AU507661B2 AU 507661 B2 AU507661 B2 AU 507661B2 AU 20878/76 A AU20878/76 A AU 20878/76A AU 2087876 A AU2087876 A AU 2087876A AU 507661 B2 AU507661 B2 AU 507661B2
Authority
AU
Australia
Prior art keywords
acid ester
phenylacetic acid
ester derivatives
derivatives
phenylacetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU20878/76A
Other versions
AU2087876A (en
Inventor
K. Nakagawa A. Ishikura Y. and Ide Noda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Publication of AU2087876A publication Critical patent/AU2087876A/en
Application granted granted Critical
Publication of AU507661B2 publication Critical patent/AU507661B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12—Radicals substituted by oxygen atoms
AU20878/76A 1975-12-24 1976-12-23 Phenylacetic acid ester derivatives Expired AU507661B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JPJP156799/7 1975-12-24
JP50156799A JPS5826744B2 (en) 1975-12-24 1975-12-24 Shinkinapropionsan Ester Yudou Tino Seizou

Publications (2)

Publication Number Publication Date
AU2087876A AU2087876A (en) 1978-06-29
AU507661B2 true AU507661B2 (en) 1980-02-21

Family

ID=15635562

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20878/76A Expired AU507661B2 (en) 1975-12-24 1976-12-23 Phenylacetic acid ester derivatives

Country Status (9)

Country Link
JP (1) JPS5826744B2 (en)
AU (1) AU507661B2 (en)
CA (1) CA1076134A (en)
CH (1) CH617919A5 (en)
DE (1) DE2658610C2 (en)
FR (1) FR2336126A1 (en)
GB (1) GB1573322A (en)
NL (1) NL180381C (en)
SE (1) SE433492B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5517358A (en) * 1978-07-24 1980-02-06 Teikoku Seiyaku Kk Butyl propionate derivative, its preparation, and antiphlogistic and analgesic comprising it
JPS54144336A (en) * 1978-07-24 1979-11-10 Teikoku Seiyaku Kk Propionic acid propylester derivative*its manufacture and antiiinflammatory and sedative agent containing it
JPS5587770A (en) * 1978-12-27 1980-07-02 Hisamitsu Pharmaceut Co Inc Preparation of 2-(p-isobutylphenyl)propionic acid 2-pyridinemethyl ester
JPS57203035A (en) * 1981-06-05 1982-12-13 Taisho Pharmaceut Co Ltd Carboxylic acid ester
DE3225290A1 (en) * 1982-07-07 1984-01-12 Merck Patent Gmbh RING CONNECTIONS
YU43408B (en) * 1985-04-26 1989-06-30 Lek Tovarna Farmacevtskih Process for preparation of 2-(4-isobuthylphenyl)-prophiohydroxamic acid
JPH0635378B2 (en) * 1985-06-27 1994-05-11 ポ−ラ化成工業株式会社 Cosmetics
ES2004447A6 (en) * 1987-07-06 1989-01-01 Sune Coma Nuria New 2-(P-isobutylphenyl)-propionic acid ester and process for the preparation thereof.
DE3811118C1 (en) * 1988-03-31 1989-10-12 Merckle Gmbh, 7902 Blaubeuren, De
IT1217589B (en) * 1988-05-13 1990-03-30 Pulitzer Italiana ANTI-INFLAMMATORY AGENT FOR THERAPY OF PROSTATIC HYPERTROPHY, ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
JPH0639449B2 (en) * 1989-04-10 1994-05-25 エーザイ株式会社 Polyprenyl compound, method for producing the same, and medicament containing the same
UA34430C2 (en) 1991-05-13 2001-03-15 Дзе Бутс Компані Плс S(-)sodium2-(4-isobutyl-phenyl)propionate dihydrate useful for treatment of inflammation, ache and hyperthermia, a pharmaceutical composition based thereon and a process for preparation of s(-)sodium2-(4-isobutyl- phenyl)propionate
US6399618B1 (en) 1997-07-09 2002-06-04 Cardiome Pharma Corp Compositions and methods for modulating sexual activity
CN103948571A (en) * 2006-07-18 2014-07-30 天津昕晨泰飞尔医药科技有限公司 Water-soluble ibuprofen prodrug with high skin penetration rate and positive charge
JP5424880B2 (en) * 2006-08-15 2014-02-26 テックフィールズ バイオケム カンパニー リミテッド Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin permeability
RU2509076C2 (en) 2007-06-04 2014-03-10 Текфилдз Инк Prodrugs of nonsteroid anti-inflammatory agents (nsaia) with very high speed of penetration through skin and membranes, and new medical applications of above said prodrugs
US9809557B2 (en) 2011-10-31 2017-11-07 Claus Selch Larsen Prodrugs of non-steroid anti-inflammatory agents (NSAIDS)
US9273891B2 (en) 2012-12-13 2016-03-01 Whirlpool Corporation Rotational ice maker
US9557087B2 (en) 2012-12-13 2017-01-31 Whirlpool Corporation Clear ice making apparatus having an oscillation frequency and angle
US9470448B2 (en) 2012-12-13 2016-10-18 Whirlpool Corporation Apparatus to warm plastic side of mold
US9500398B2 (en) 2012-12-13 2016-11-22 Whirlpool Corporation Twist harvest ice geometry
CN105461731B (en) * 2014-08-07 2017-05-24 富力 Phillygenin ibuprofen ester, preparation and applications thereof
WO2016065269A2 (en) 2014-10-23 2016-04-28 Whirlpool Corporation Method and apparatus for increasing rate of ice production in an automatic ice maker
JP6153264B2 (en) * 2015-01-05 2017-06-28 テックフィールズ インコーポレイテッド NSAIA prodrug with very fast skin and membrane permeation rate and novel pharmaceutical use thereof
CN109134261A (en) * 2017-06-15 2019-01-04 北京蓝丹医药科技有限公司 A kind of loxoprofen derivative
CN109134262A (en) * 2017-06-15 2019-01-04 北京蓝丹医药科技有限公司 A kind of loxoprofen derivative
US10907874B2 (en) 2018-10-22 2021-02-02 Whirlpool Corporation Ice maker downspout

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents

Also Published As

Publication number Publication date
CA1076134A (en) 1980-04-22
CH617919A5 (en) 1980-06-30
FR2336126A1 (en) 1977-07-22
JPS5826744B2 (en) 1983-06-04
SE433492B (en) 1984-05-28
NL7614308A (en) 1977-06-28
AU2087876A (en) 1978-06-29
DE2658610A1 (en) 1977-07-07
SE7613651L (en) 1977-06-25
NL180381B (en) 1986-09-16
NL180381C (en) 1987-02-16
DE2658610C2 (en) 1982-12-23
JPS5278848A (en) 1977-07-02
GB1573322A (en) 1980-08-20
FR2336126B1 (en) 1979-03-09

Similar Documents

Publication Publication Date Title
AU507661B2 (en) Phenylacetic acid ester derivatives
AU511853B2 (en) l-Phenyl-2-Oxo-Pyrroliaine-4-carboxylic acid derivatives
AU513286B2 (en) Pridyloxy-phenoxy-alkane carboxylic acid derivatives
AU512971B2 (en) Phenoxypropionic acid derivatives
AU522170B2 (en) Phenoxyphenylthioalkane carboxylic acid derivatives
AU501045B2 (en) Phenoxyphenoxyalkanr carboxlic acid derivatives
AU501066B2 (en) Fudidic acid derivatives
AU497932B2 (en) Phenoxyalkylcarboxylic acid derivatives
AU500761B2 (en) Phenoxyalkylcarboxylic acid derivatives
AU510126B2 (en) Derivatives of phenoxyalklcarboxylic acids
GB1554299A (en) Phenylacetic acid derivatives
AU511662B2 (en) Indoleacetic acid ester derivatives
AU507111B2 (en) Deposit-steroid esters
AU510575B2 (en) 2-arylpropionic acids
AU499163B2 (en) Azanaphthalene acetic acid derivatives
AU502396B2 (en) Dithiocapbamic acid esters
AU500980B2 (en) Oxanilic acid derivatives
AU507454B2 (en) Phosphoric acid amide esters
AU500400B2 (en) Ethyl-propyl-[pyrayolo-pyrimidinyl] -thionothiolphosphoric acid esters
AU497577B2 (en) Clavulanic acid derivatives
AU3137877A (en) 1-aziridine-carboxylic acid ester derivatives
AU496915B2 (en) prostanoic ACID DERIVATIVES
AU496903B2 (en) Substituted phenylacetic acid thioamides
AU492676B2 (en) Thiaprostanoic acid derivatives
AU495541B2 (en) Phenylene-dioxamic acid derivatives