FR2332014A1 - Derives n-alcoyles de thienamycine utiles en tant qu'antibiotiques - Google Patents

Derives n-alcoyles de thienamycine utiles en tant qu'antibiotiques

Info

Publication number
FR2332014A1
FR2332014A1 FR7634884A FR7634884A FR2332014A1 FR 2332014 A1 FR2332014 A1 FR 2332014A1 FR 7634884 A FR7634884 A FR 7634884A FR 7634884 A FR7634884 A FR 7634884A FR 2332014 A1 FR2332014 A1 FR 2332014A1
Authority
FR
France
Prior art keywords
thienamycin
antibiotics
alkyl derivatives
derivatives useful
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7634884A
Other languages
English (en)
French (fr)
Other versions
FR2332014B1 (online.php
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2332014A1 publication Critical patent/FR2332014A1/fr
Application granted granted Critical
Publication of FR2332014B1 publication Critical patent/FR2332014B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7634884A 1975-11-21 1976-11-19 Derives n-alcoyles de thienamycine utiles en tant qu'antibiotiques Granted FR2332014A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63429775A 1975-11-21 1975-11-21

Publications (2)

Publication Number Publication Date
FR2332014A1 true FR2332014A1 (fr) 1977-06-17
FR2332014B1 FR2332014B1 (online.php) 1978-11-10

Family

ID=24543224

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7634884A Granted FR2332014A1 (fr) 1975-11-21 1976-11-19 Derives n-alcoyles de thienamycine utiles en tant qu'antibiotiques

Country Status (8)

Country Link
JP (1) JPS5277085A (online.php)
CH (1) CH628051A5 (online.php)
DE (1) DE2652676A1 (online.php)
DK (1) DK523676A (online.php)
FR (1) FR2332014A1 (online.php)
GB (1) GB1570988A (online.php)
NL (1) NL7612937A (online.php)
SE (1) SE7612964L (online.php)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
DE2966187D1 (en) * 1978-08-23 1983-10-27 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
DE3167774D1 (en) * 1980-02-28 1985-01-31 Fujisawa Pharmaceutical Co 4-substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics
JPS5798257A (en) * 1980-12-10 1982-06-18 Sankyo Co Ltd 3,4-disubstituted azetidine-2-one compound and its preparation
EP0062407A1 (en) * 1981-03-10 1982-10-13 Beecham Group Plc Therapeutic compounds containing beta-lactams
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
BE897086A (fr) * 1982-06-18 1983-12-19 Bristol Myers Co Produits nouveaux de la classe des carbapenems et leur application en tant qu'antibiotiques
AU2004296261B2 (en) * 2003-12-09 2007-08-23 Choongwae Pharm. Co. A new process for preparation of imipenem

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
JPS5277085A (en) 1977-06-29
SE7612964L (sv) 1977-05-22
CH628051A5 (en) 1982-02-15
DE2652676A1 (de) 1977-06-02
DK523676A (da) 1977-05-22
GB1570988A (en) 1980-07-09
FR2332014B1 (online.php) 1978-11-10
NL7612937A (nl) 1977-05-24

Similar Documents

Publication Publication Date Title
RO68460A (ro) Procedeu pentru prepararea unor derivati de azetidinona
BE847044A (fr) Derives de l'acide clavulanique,
BE821406A (fr) Derives de 1
IE34794L (en) Sulphur-containing 1, 4-dihydropyridine derivatives
FR2332013A1 (fr) Derives n-acyles et carboxyles de thienamycine utiles comme antibiotiques
BE810808A (fr) Derives de l'azetidine
FR2332747A1 (fr) Derives d'a-aminocetones
BE825325A (fr) Derives de l'azetidine
FR2285366A1 (fr) Derives de l'anthracycline
FR2322604A1 (fr) Derives 3-triazolylthio d'ureido-7a-methoxy-ou demethoxycephalosporines
ZA766973B (en) Substituted n-methylene derivatives of thienamycin
FR2327776A1 (fr) Derives de l'acide clavulanique
BE825128R (fr) Derives de l'indole
BE847978A (fr) Derives de l'hydantoine,
BE847046A (fr) Derives de l'acide clavulanique,
FR2327774A1 (fr) Derives de l'acide clavulanique
FR2332012A1 (fr) Derives n-methylene substitues de thienamycine utiles comme antibiotiques
FR2332016A1 (fr) Derives n-acyles de thienamycine utiles comme antibiotiques
FR2317931A1 (fr) Derives de quinoxaline en tant qu'agents immunoregulateurs
FR2322122A1 (fr) Derives de tetracyclotetradecene
BE821335A (fr) Derives de l'erythrodiol
BE847045A (fr) Derives de l'acide clavulanique,
ZA761859B (en) Novel substituted sulfonamide derivatives as anthelmintic agents
SE7413949L (online.php)
BE849109A (fr) Derives d'azetidinone

Legal Events

Date Code Title Description
ST Notification of lapse