FR2325369A1 - (2)-Nitro (3)-phenyl benzofuran-alkanoic acids - with antibacterial, antifungal and antiprotozoal activity - Google Patents

(2)-Nitro (3)-phenyl benzofuran-alkanoic acids - with antibacterial, antifungal and antiprotozoal activity

Info

Publication number
FR2325369A1
FR2325369A1 FR7628662A FR7628662A FR2325369A1 FR 2325369 A1 FR2325369 A1 FR 2325369A1 FR 7628662 A FR7628662 A FR 7628662A FR 7628662 A FR7628662 A FR 7628662A FR 2325369 A1 FR2325369 A1 FR 2325369A1
Authority
FR
France
Prior art keywords
antifungal
nitro
antibacterial
phenyl
alkanoic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7628662A
Other languages
French (fr)
Other versions
FR2325369B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of FR2325369A1 publication Critical patent/FR2325369A1/en
Application granted granted Critical
Publication of FR2325369B1 publication Critical patent/FR2325369B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/12—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Abstract

New benzofduran derivs. of formula (I) and their esters, amides, acids halides and salts: (where X is halogen, lower alkyl, lower alkoxy, NO2, Ph, CN or CF3; n = 0-2; R is 1-4C alkylene or 2-4C alkenylene; Y is Me, MeO, halogen or H). Cpds. (I) are antimicrobial agents, all with antibacterial activity and some also with antifungal and antiprotozoal (esp. trichomonacidal) activity. They can be used as medicaments, disinfectants and animal growth promoters. A typical cpds. is 2-nitro-3-phenyl-6-benzofuranacetic acid. In an example, this isd prepd. by nitrating 3-phenyl-6-benzofuranacetic acid.
FR7628662A 1975-09-24 1976-09-23 (2)-Nitro (3)-phenyl benzofuran-alkanoic acids - with antibacterial, antifungal and antiprotozoal activity Granted FR2325369A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61627775A 1975-09-24 1975-09-24

Publications (2)

Publication Number Publication Date
FR2325369A1 true FR2325369A1 (en) 1977-04-22
FR2325369B1 FR2325369B1 (en) 1979-02-23

Family

ID=24468746

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7628662A Granted FR2325369A1 (en) 1975-09-24 1976-09-23 (2)-Nitro (3)-phenyl benzofuran-alkanoic acids - with antibacterial, antifungal and antiprotozoal activity

Country Status (21)

Country Link
JP (1) JPS5239666A (en)
AR (1) AR215598A1 (en)
AU (1) AU1804276A (en)
BE (1) BE846502A (en)
CS (1) CS191319B2 (en)
DD (1) DD130786A5 (en)
DE (1) DE2642840A1 (en)
DK (1) DK413676A (en)
EG (1) EG12427A (en)
ES (1) ES451542A1 (en)
FI (1) FI762715A (en)
FR (1) FR2325369A1 (en)
IL (1) IL50543A0 (en)
IT (1) IT1070556B (en)
NL (1) NL7610166A (en)
NO (1) NO763144L (en)
OA (1) OA05441A (en)
PT (1) PT65632B (en)
SE (1) SE7610149L (en)
SU (1) SU692561A3 (en)
ZA (1) ZA765079B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4031128A4 (en) * 2019-09-16 2023-12-13 Koda Therapeutics, LLC Antimicrobial agents and compositions and uses thereof

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128659A (en) 1977-12-19 1978-12-05 Riker Laboratories, Inc. Antimicrobial polycyclic nitrofurans
US4143152A (en) 1977-12-19 1979-03-06 Riker Laboratories, Inc. Anti-microbial (2-nitro-3-phenyl benzofuranyl)-phenylalkanoic acids and derivatives
US4153721A (en) 1977-12-19 1979-05-08 Riker Laboratories, Inc. Derivatives of 2-nitrobenzofuran
US4154847A (en) 1978-06-26 1979-05-15 Riker Laboratories, Inc. Derivatives of 2-nitro-3-phenylbenzofurancarboxaldehydes
US4174403A (en) 1978-06-26 1979-11-13 Riker Laboratories, Inc. 5,6-Methylenedioxy-2-nitro-3-phenylbenzofurans

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4031128A4 (en) * 2019-09-16 2023-12-13 Koda Therapeutics, LLC Antimicrobial agents and compositions and uses thereof

Also Published As

Publication number Publication date
DD130786A5 (en) 1978-05-03
SE7610149L (en) 1977-03-25
DE2642840A1 (en) 1977-04-07
PT65632A (en) 1976-10-01
DK413676A (en) 1977-03-25
FI762715A (en) 1977-03-25
SU692561A3 (en) 1979-10-15
NL7610166A (en) 1977-03-28
FR2325369B1 (en) 1979-02-23
IT1070556B (en) 1985-03-29
JPS5239666A (en) 1977-03-28
NO763144L (en) 1977-03-25
OA05441A (en) 1981-03-31
CS191319B2 (en) 1979-06-29
ZA765079B (en) 1977-08-31
AR215598A1 (en) 1979-10-31
ES451542A1 (en) 1977-10-01
BE846502A (en) 1977-03-23
IL50543A0 (en) 1976-11-30
AU1804276A (en) 1978-04-06
PT65632B (en) 1978-04-05
EG12427A (en) 1979-03-31

Similar Documents

Publication Publication Date Title
GB1409693A (en) Triazolobenzodiazepines
MY102919A (en) Pleuromutilin derivatives process for their preparation and their use.
FR2325369A1 (en) (2)-Nitro (3)-phenyl benzofuran-alkanoic acids - with antibacterial, antifungal and antiprotozoal activity
GB1445387A (en) N-1-alkoxycarbonyl-ethyl-n-haloacetyl-2,6-dialkylanilines and their microbicidal use
IE36127L (en) 3-benzylpyridines
FR2325370A1 (en) (2)-Nitro-(3)-phenyl-benzofuran derivs. - with antimicrobial, esp. antibacterial activity
GB1343527A (en) Amino-propanol derivatives
ES465668A1 (en) Pesticidal phenoxy benzyl pentene carboxylate(s) - are prepd. by esterifying a phenoxy benzyl alcohol with a pentene carboxylic acid
GB1463219A (en) Thyronamine derivatives
FR2249616A1 (en) Fungicidal compositions contg 1-aralkyl benzimidazoles - for treatment of plants and seeds
GB1462095A (en) Substituted triazolo-1,5-benzodiazepines
GB1504862A (en) Terpeno-phenoxyalkylamines
SE430204B (en) USE OF CERTAIN OMEGA-AMINOCARBOXYLIC ACID AMOIDS AS ANTIMICROBIAL AND ALGICIDAL AGENTS
ES451160A1 (en) Insect control by inhibiting juvenile hormone activity
GB1255751A (en) Herbicidal agents
GB1455169A (en) Amidic derivatives of nicotinic acid
GB1215609A (en) Coumarin derivatives
GB1330667A (en) N-o-fluorophenylureas their manufacture and their use
NL7402361A (en) ORGANIC HEXAFLUORANTIMONIC ACID SALTS AND THEIR USE AS CATALYSTS FOR CATIONIC POLYMERIZATIONS.
GB1416218A (en) Formamidines and their use in pest control
GB1289085A (en)
IE35783B1 (en) New molecular complexes and their use in animal husbandry
GB1458825A (en) Herbicidal preparations containing phenoxy-carboxylic acid oxime -esters and the manufacture of the latter
FR2304347A1 (en) N-alkyl-N-phenyl salicylanilides - with antibacterial, antifungal, and anthelmintic activity for use in human and veterinary medicine and as plant protection agents
JPS55129275A (en) Farnesylacetic acid amide bearing piperazine ring or its salt

Legal Events

Date Code Title Description
ST Notification of lapse