FR2322851A1 - Procede de preparation de l'(hydroxy-2 indanyl-2)-1 propylamine - Google Patents
Procede de preparation de l'(hydroxy-2 indanyl-2)-1 propylamineInfo
- Publication number
- FR2322851A1 FR2322851A1 FR7527346A FR7527346A FR2322851A1 FR 2322851 A1 FR2322851 A1 FR 2322851A1 FR 7527346 A FR7527346 A FR 7527346A FR 7527346 A FR7527346 A FR 7527346A FR 2322851 A1 FR2322851 A1 FR 2322851A1
- Authority
- FR
- France
- Prior art keywords
- cyanhydrin
- reaction
- indanone
- indanyl
- propylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000005670 ethenylalkyl group Chemical group 0.000 title abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 title abstract 2
- QIKYQCSSEDHCPA-UHFFFAOYSA-N N-(2,3-dihydro-1H-inden-1-yl)-N-propylhydroxylamine Chemical compound ON(CCC)C1CCC2=CC=CC=C12 QIKYQCSSEDHCPA-UHFFFAOYSA-N 0.000 title 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 6
- WSGYTJNNHPZFKR-UHFFFAOYSA-N 3-hydroxypropanenitrile Chemical compound OCCC#N WSGYTJNNHPZFKR-UHFFFAOYSA-N 0.000 abstract 2
- FJKIXWOMBXYWOQ-UHFFFAOYSA-N ethenoxyethane Chemical compound CCOC=C FJKIXWOMBXYWOQ-UHFFFAOYSA-N 0.000 abstract 2
- 150000002466 imines Chemical class 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 229910010084 LiAlH4 Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000001539 anorectic effect Effects 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 206010061428 decreased appetite Diseases 0.000 abstract 1
- -1 ethylmagnesium halide Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- UMJJFEIKYGFCAT-UHFFFAOYSA-N indan-2-one Chemical compound C1=CC=C2CC(=O)CC2=C1 UMJJFEIKYGFCAT-UHFFFAOYSA-N 0.000 abstract 1
- QTZFSVVIXMRRLW-UHFFFAOYSA-N indanorex Chemical compound C1=CC=C2CC(C(N)CC)(O)CC2=C1 QTZFSVVIXMRRLW-UHFFFAOYSA-N 0.000 abstract 1
- 230000002366 lipolytic effect Effects 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- FRIJBUGBVQZNTB-UHFFFAOYSA-M magnesium;ethane;bromide Chemical compound [Mg+2].[Br-].[CH2-]C FRIJBUGBVQZNTB-UHFFFAOYSA-M 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7527346A FR2322851A1 (fr) | 1975-09-05 | 1975-09-05 | Procede de preparation de l'(hydroxy-2 indanyl-2)-1 propylamine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7527346A FR2322851A1 (fr) | 1975-09-05 | 1975-09-05 | Procede de preparation de l'(hydroxy-2 indanyl-2)-1 propylamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2322851A1 true FR2322851A1 (fr) | 1977-04-01 |
| FR2322851B1 FR2322851B1 (enExample) | 1978-06-23 |
Family
ID=9159682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7527346A Granted FR2322851A1 (fr) | 1975-09-05 | 1975-09-05 | Procede de preparation de l'(hydroxy-2 indanyl-2)-1 propylamine |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2322851A1 (enExample) |
-
1975
- 1975-09-05 FR FR7527346A patent/FR2322851A1/fr active Granted
Non-Patent Citations (1)
| Title |
|---|
| COMPT. REND. 237, PAGES 1006 - 1008 1953 ) * |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2322851B1 (enExample) | 1978-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |