FR2304340A1 - Nouveaux derives de prostaglandine, leur procede de preparation ainsi que les compositions therapeutiques les contenant - Google Patents

Nouveaux derives de prostaglandine, leur procede de preparation ainsi que les compositions therapeutiques les contenant

Info

Publication number
FR2304340A1
FR2304340A1 FR7607794A FR7607794A FR2304340A1 FR 2304340 A1 FR2304340 A1 FR 2304340A1 FR 7607794 A FR7607794 A FR 7607794A FR 7607794 A FR7607794 A FR 7607794A FR 2304340 A1 FR2304340 A1 FR 2304340A1
Authority
FR
France
Prior art keywords
preparation process
compositions containing
therapeutic compositions
prostaglandin derivatives
new prostaglandin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7607794A
Other languages
English (en)
French (fr)
Other versions
FR2304340B1 (ja
Inventor
Alain Jean
Charles Pigerol
Pierre Eymard
Jacques Simiand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of FR2304340A1 publication Critical patent/FR2304340A1/fr
Application granted granted Critical
Publication of FR2304340B1 publication Critical patent/FR2304340B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7607794A 1975-03-21 1976-03-18 Nouveaux derives de prostaglandine, leur procede de preparation ainsi que les compositions therapeutiques les contenant Granted FR2304340A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB12034/75A GB1529852A (en) 1975-03-21 1975-03-21 8-azaprostaglandins and process for the preparation thereof

Publications (2)

Publication Number Publication Date
FR2304340A1 true FR2304340A1 (fr) 1976-10-15
FR2304340B1 FR2304340B1 (ja) 1979-06-29

Family

ID=9997230

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7607794A Granted FR2304340A1 (fr) 1975-03-21 1976-03-18 Nouveaux derives de prostaglandine, leur procede de preparation ainsi que les compositions therapeutiques les contenant

Country Status (26)

Country Link
JP (1) JPS607602B2 (ja)
AR (1) AR213172A1 (ja)
AT (1) AT348163B (ja)
AU (1) AU501105B2 (ja)
BE (1) BE839761A (ja)
CA (1) CA1076587A (ja)
CH (2) CH611881A5 (ja)
DE (1) DE2612114A1 (ja)
DK (1) DK140937B (ja)
ES (2) ES446239A1 (ja)
FI (1) FI61692C (ja)
FR (1) FR2304340A1 (ja)
GB (1) GB1529852A (ja)
HU (1) HU173348B (ja)
IE (1) IE42966B1 (ja)
IT (1) IT1061011B (ja)
MX (1) MX3301E (ja)
NL (1) NL7602891A (ja)
NO (1) NO144147C (ja)
NZ (1) NZ180251A (ja)
OA (1) OA05279A (ja)
PT (1) PT64919B (ja)
SE (1) SE418290B (ja)
SU (1) SU614746A3 (ja)
YU (1) YU73876A (ja)
ZA (1) ZA761448B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097489A (en) * 1977-06-17 1978-06-27 The Upjohn Company 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds
US5540618A (en) * 1994-10-28 1996-07-30 National University Of Singapore Passive attenuator for shelter protection against explosions
WO2003074483A1 (fr) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif

Also Published As

Publication number Publication date
FI760744A (ja) 1976-09-22
GB1529852A (en) 1978-10-25
FI61692C (fi) 1982-09-10
JPS51138671A (en) 1976-11-30
DE2612114A1 (de) 1976-10-07
ES446239A1 (es) 1977-07-01
DK140937C (ja) 1980-05-19
FR2304340B1 (ja) 1979-06-29
ATA195676A (de) 1978-06-15
DK88276A (ja) 1976-09-22
PT64919A (en) 1976-04-01
CH611604A5 (en) 1979-06-15
OA05279A (fr) 1981-02-28
HU173348B (hu) 1979-04-28
ES458389A1 (es) 1978-02-16
IE42966B1 (en) 1980-11-19
BE839761A (fr) 1976-09-20
CA1076587A (en) 1980-04-29
AU1189976A (en) 1977-09-15
IT1061011B (it) 1982-10-20
YU73876A (en) 1982-10-31
NO144147C (no) 1981-07-15
PT64919B (en) 1977-08-24
JPS607602B2 (ja) 1985-02-26
NZ180251A (en) 1978-07-28
NO760994L (ja) 1976-09-22
MX3301E (es) 1980-09-03
IE42966L (en) 1976-09-21
AU501105B2 (en) 1979-06-14
CH611881A5 (en) 1979-06-29
NL7602891A (nl) 1976-09-23
AR213172A1 (es) 1978-12-29
SU614746A3 (ru) 1978-07-05
SE7603400L (sv) 1976-09-22
AT348163B (de) 1979-02-12
NO144147B (no) 1981-03-23
ZA761448B (en) 1977-03-30
FI61692B (fi) 1982-05-31
DK140937B (da) 1979-12-10
SE418290B (sv) 1981-05-18

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