FR2303542A1 - Amides de la pyrrolidino ethyl amine utilisables en therapeutique pulmonaire - Google Patents
Amides de la pyrrolidino ethyl amine utilisables en therapeutique pulmonaireInfo
- Publication number
- FR2303542A1 FR2303542A1 FR7507799A FR7507799A FR2303542A1 FR 2303542 A1 FR2303542 A1 FR 2303542A1 FR 7507799 A FR7507799 A FR 7507799A FR 7507799 A FR7507799 A FR 7507799A FR 2303542 A1 FR2303542 A1 FR 2303542A1
- Authority
- FR
- France
- Prior art keywords
- alpha
- amides
- phenyl
- ethyl amine
- amine used
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WRXNJTBODVGDRY-UHFFFAOYSA-N 2-pyrrolidin-1-ylethanamine Chemical compound NCCN1CCCC1 WRXNJTBODVGDRY-UHFFFAOYSA-N 0.000 title abstract 3
- 150000001408 amides Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000002685 pulmonary effect Effects 0.000 title 1
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 abstract 2
- NQRADKZWOUSTQL-UHFFFAOYSA-N 2-phenyl-n-(2-pyrrolidin-1-ylethyl)butanamide Chemical compound C=1C=CC=CC=1C(CC)C(=O)NCCN1CCCC1 NQRADKZWOUSTQL-UHFFFAOYSA-N 0.000 abstract 1
- QGXMHCMPIAYMGT-UHFFFAOYSA-N 2-phenylbutanoyl chloride Chemical compound CCC(C(Cl)=O)C1=CC=CC=C1 QGXMHCMPIAYMGT-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical group Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000003434 antitussive agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 229960004126 codeine Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- JIFBZEZAAPHGBB-UHFFFAOYSA-N phenothiazine-10-carboxylic acid Chemical compound C1=CC=C2N(C(=O)O)C3=CC=CC=C3SC2=C1 JIFBZEZAAPHGBB-UHFFFAOYSA-N 0.000 abstract 1
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7507799A FR2303542A1 (fr) | 1975-03-12 | 1975-03-12 | Amides de la pyrrolidino ethyl amine utilisables en therapeutique pulmonaire |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7507799A FR2303542A1 (fr) | 1975-03-12 | 1975-03-12 | Amides de la pyrrolidino ethyl amine utilisables en therapeutique pulmonaire |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2303542A1 true FR2303542A1 (fr) | 1976-10-08 |
| FR2303542B1 FR2303542B1 (https=) | 1979-07-06 |
Family
ID=9152495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7507799A Granted FR2303542A1 (fr) | 1975-03-12 | 1975-03-12 | Amides de la pyrrolidino ethyl amine utilisables en therapeutique pulmonaire |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2303542A1 (https=) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2506765A1 (fr) * | 1981-05-27 | 1982-12-03 | Fabre Sa Pierre | Aryl carboxamides de la pyrrolidino ethylamine, leur preparation et leur application en tant que medicaments antitussifs |
| EP0098743A1 (en) * | 1982-06-30 | 1984-01-18 | Ruey J. Dr. Yu | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use |
| EP0383256A3 (en) * | 1989-02-14 | 1992-01-02 | Fujisawa Pharmaceutical Co., Ltd. | A novel substituted-acetamide compound and a process for the preparation thereof |
| US5192779A (en) * | 1989-02-14 | 1993-03-09 | Fujisawa Pharmaceutical Co., Ltd. | Substituted-acetamide compound and a process for the preparation thereof |
| WO1996005837A1 (de) * | 1994-08-25 | 1996-02-29 | Bayer Aktiengesellschaft | Verwendung von n-substituierten phenothiazinen |
| WO2001092240A1 (en) * | 2000-05-29 | 2001-12-06 | Dalhousie University | Novel n-substituted phenothiazines and their use as modulators of serine hydrolase enzymes |
-
1975
- 1975-03-12 FR FR7507799A patent/FR2303542A1/fr active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2506765A1 (fr) * | 1981-05-27 | 1982-12-03 | Fabre Sa Pierre | Aryl carboxamides de la pyrrolidino ethylamine, leur preparation et leur application en tant que medicaments antitussifs |
| EP0098743A1 (en) * | 1982-06-30 | 1984-01-18 | Ruey J. Dr. Yu | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use |
| EP0383256A3 (en) * | 1989-02-14 | 1992-01-02 | Fujisawa Pharmaceutical Co., Ltd. | A novel substituted-acetamide compound and a process for the preparation thereof |
| US5192779A (en) * | 1989-02-14 | 1993-03-09 | Fujisawa Pharmaceutical Co., Ltd. | Substituted-acetamide compound and a process for the preparation thereof |
| WO1996005837A1 (de) * | 1994-08-25 | 1996-02-29 | Bayer Aktiengesellschaft | Verwendung von n-substituierten phenothiazinen |
| WO2001092240A1 (en) * | 2000-05-29 | 2001-12-06 | Dalhousie University | Novel n-substituted phenothiazines and their use as modulators of serine hydrolase enzymes |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2303542B1 (https=) | 1979-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |