FR2300757A1 - Pr - Google Patents
PrInfo
- Publication number
- FR2300757A1 FR2300757A1 FR7603045A FR7603045A FR2300757A1 FR 2300757 A1 FR2300757 A1 FR 2300757A1 FR 7603045 A FR7603045 A FR 7603045A FR 7603045 A FR7603045 A FR 7603045A FR 2300757 A1 FR2300757 A1 FR 2300757A1
- Authority
- FR
- France
- Prior art keywords
- phenylethanolamine
- hypertensives
- useful
- reducing
- derivs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical compound NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 title abstract 4
- 230000001631 hypertensive effect Effects 0.000 title abstract 2
- 229950006768 phenylethanolamine Drugs 0.000 title abstract 2
- 150000001540 azides Chemical class 0.000 title 1
- 239000005555 hypertensive agent Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 2,5-dimethoxyphenyl Chemical group 0.000 abstract 1
- 125000004208 3-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C([H])C(*)=C1[H] 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- UGUUDTWORXNLAK-UHFFFAOYSA-N azidoalcohol Chemical class ON=[N+]=[N-] UGUUDTWORXNLAK-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 125000005207 tetraalkylammonium group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752506110 DE2506110C2 (de) | 1975-02-13 | 1975-02-13 | Verfahren zur Herstellung von 2- Amino-N-(β-hydroxy-2,5-dimethoxy-phenäthyl)-acetamid (Midodrin) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2300757A1 true FR2300757A1 (fr) | 1976-09-10 |
| FR2300757B1 FR2300757B1 (enrdf_load_stackoverflow) | 1980-01-25 |
Family
ID=5938824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7603045A Granted FR2300757A1 (fr) | 1975-02-13 | 1976-02-04 | Pr |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS51105026A (enrdf_load_stackoverflow) |
| BE (1) | BE838512A (enrdf_load_stackoverflow) |
| CH (1) | CH597157A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2506110C2 (enrdf_load_stackoverflow) |
| FR (1) | FR2300757A1 (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2510560A1 (fr) * | 1981-07-29 | 1983-02-04 | Synthelabo | Procede de preparation d'amino-4 butyramide |
| WO2001079154A3 (en) * | 2000-04-17 | 2002-03-21 | Novartis Ag | Synthesis of midodrine hci from a novel intermediate 1-(2',5'-dimethoxyphenyl)-2-azidoethanone |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004018409A1 (en) | 2002-08-21 | 2004-03-04 | Sanmar Speciality Chemicals Ltd | An improved process for the synthesis of (±) 2-amino-n-[2,(s,5-dimethoxyphenyl)-2-hydroxyethyl] acetamide monohydrochloride |
-
1975
- 1975-02-13 DE DE19752506110 patent/DE2506110C2/de not_active Expired
-
1976
- 1976-01-28 CH CH103676A patent/CH597157A5/xx not_active IP Right Cessation
- 1976-02-04 FR FR7603045A patent/FR2300757A1/fr active Granted
- 1976-02-12 BE BE164286A patent/BE838512A/xx not_active IP Right Cessation
- 1976-02-13 JP JP1408276A patent/JPS51105026A/ja active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2510560A1 (fr) * | 1981-07-29 | 1983-02-04 | Synthelabo | Procede de preparation d'amino-4 butyramide |
| EP0071500A1 (fr) * | 1981-07-29 | 1983-02-09 | Synthelabo | Procédé de préparation d'amino-4 butyramide |
| WO2001079154A3 (en) * | 2000-04-17 | 2002-03-21 | Novartis Ag | Synthesis of midodrine hci from a novel intermediate 1-(2',5'-dimethoxyphenyl)-2-azidoethanone |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5747986B2 (enrdf_load_stackoverflow) | 1982-10-13 |
| FR2300757B1 (enrdf_load_stackoverflow) | 1980-01-25 |
| CH597157A5 (enrdf_load_stackoverflow) | 1978-03-31 |
| JPS51105026A (ja) | 1976-09-17 |
| DE2506110A1 (de) | 1976-08-26 |
| BE838512A (fr) | 1976-08-12 |
| DE2506110C2 (de) | 1983-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| CC | Supplementary certificate of protection laid open to the public (law of 25 june 1990) |
Free format text: 92C0499, 920626 |
|
| CB | Supplementary certificate of protection granted (law of 25 june 1990) |
Free format text: 92C0499, 760204 |
|
| CL | Concession to grant licenses |