FR2291763A1 - Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression - Google Patents
Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppressionInfo
- Publication number
- FR2291763A1 FR2291763A1 FR7535387A FR7535387A FR2291763A1 FR 2291763 A1 FR2291763 A1 FR 2291763A1 FR 7535387 A FR7535387 A FR 7535387A FR 7535387 A FR7535387 A FR 7535387A FR 2291763 A1 FR2291763 A1 FR 2291763A1
- Authority
- FR
- France
- Prior art keywords
- antitumorous
- phosphamide
- preparation
- new products
- cyclic derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010062016 Immunosuppression Diseases 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 title 1
- MCWXGJITAZMZEV-UHFFFAOYSA-N dimethoate Chemical class CNC(=O)CSP(=S)(OC)OC MCWXGJITAZMZEV-UHFFFAOYSA-N 0.000 title 1
- 230000001506 immunosuppresive effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000008569 process Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/14—Esters of phosphoric acids containing P(=O)-halide groups
- C07F9/1403—Esters of phosphoric acids containing P(=O)-halide groups containing the structure Hal-P(=O)-O-unsaturated acyclic group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2412—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of unsaturated acyclic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49133257A JPS5159886A (pt) | 1974-11-20 | 1974-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2291763A1 true FR2291763A1 (fr) | 1976-06-18 |
Family
ID=15100374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7535387A Withdrawn FR2291763A1 (fr) | 1974-11-20 | 1975-11-19 | Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5159886A (pt) |
| AU (1) | AU500813B2 (pt) |
| CA (1) | CA1051914A (pt) |
| CH (1) | CH602777A5 (pt) |
| DE (1) | DE2552135A1 (pt) |
| FR (1) | FR2291763A1 (pt) |
| GB (1) | GB1527497A (pt) |
| NL (1) | NL7513590A (pt) |
| SE (1) | SE7513007L (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3133309A1 (de) * | 1980-09-10 | 1982-04-15 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | 4-carbamoyloxy-oxazaphosphorine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
| DE3111428A1 (de) * | 1981-03-24 | 1982-10-07 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
| ZA851062B (en) * | 1984-03-01 | 1985-11-27 | Asta Werke Ag Chem Fab | Salts of oxazaphosphorine derivatives and process for their production |
| ATE255899T1 (de) * | 1999-05-24 | 2003-12-15 | Southern Res Inst | Isophosphoramide-senfgasanalogen und deren verwendung |
| US7678778B2 (en) | 2004-10-25 | 2010-03-16 | Dekk-Tec, Inc. | Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents |
| US7964583B2 (en) | 2006-02-17 | 2011-06-21 | Ziopharm Oncology, Inc. | Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents |
| BRPI0809999A2 (pt) | 2007-04-06 | 2014-10-14 | Ziopharm Oncology Inc | Sais de mostarda de isofosforamida e análogos da mesma |
-
1974
- 1974-11-20 JP JP49133257A patent/JPS5159886A/ja active Pending
-
1975
- 1975-11-07 CA CA239,381A patent/CA1051914A/en not_active Expired
- 1975-11-17 GB GB47320/75A patent/GB1527497A/en not_active Expired
- 1975-11-19 FR FR7535387A patent/FR2291763A1/fr not_active Withdrawn
- 1975-11-19 CH CH1500875A patent/CH602777A5/xx not_active IP Right Cessation
- 1975-11-19 SE SE7513007A patent/SE7513007L/xx unknown
- 1975-11-20 NL NL7513590A patent/NL7513590A/xx not_active Application Discontinuation
- 1975-11-20 AU AU86816/75A patent/AU500813B2/en not_active Expired
- 1975-11-20 DE DE19752552135 patent/DE2552135A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CH602777A5 (pt) | 1978-07-31 |
| SE7513007L (sv) | 1976-05-21 |
| AU8681675A (en) | 1977-05-26 |
| AU500813B2 (en) | 1979-05-10 |
| DE2552135A1 (de) | 1976-05-26 |
| JPS5159886A (pt) | 1976-05-25 |
| NL7513590A (nl) | 1976-05-24 |
| CA1051914A (en) | 1979-04-03 |
| GB1527497A (en) | 1978-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |