FR2272659B1 - - Google Patents

Info

Publication number
FR2272659B1
FR2272659B1 FR7516620A FR7516620A FR2272659B1 FR 2272659 B1 FR2272659 B1 FR 2272659B1 FR 7516620 A FR7516620 A FR 7516620A FR 7516620 A FR7516620 A FR 7516620A FR 2272659 B1 FR2272659 B1 FR 2272659B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7516620A
Other versions
FR2272659A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of FR2272659A1 publication Critical patent/FR2272659A1/fr
Application granted granted Critical
Publication of FR2272659B1 publication Critical patent/FR2272659B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7516620A 1974-05-31 1975-05-28 Expired FR2272659B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24348/74A GB1495526A (en) 1974-05-31 1974-05-31 Chroman derivatives

Publications (2)

Publication Number Publication Date
FR2272659A1 FR2272659A1 (fr) 1975-12-26
FR2272659B1 true FR2272659B1 (fr) 1980-02-08

Family

ID=10210307

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7516620A Expired FR2272659B1 (fr) 1974-05-31 1975-05-28

Country Status (15)

Country Link
US (1) US4048317A (fr)
JP (2) JPS6044308B2 (fr)
BE (1) BE829611A (fr)
CA (1) CA1072090A (fr)
DE (1) DE2523281A1 (fr)
DK (1) DK244875A (fr)
ES (1) ES438072A1 (fr)
FR (1) FR2272659B1 (fr)
GB (1) GB1495526A (fr)
HK (1) HK20781A (fr)
IE (1) IE41539B1 (fr)
KE (1) KE3124A (fr)
MY (1) MY8100356A (fr)
NL (1) NL7506421A (fr)
ZA (1) ZA753076B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062870A (en) * 1974-05-31 1977-12-13 Beecham Group Limited Chroman derivatives
US4542150A (en) * 1975-09-17 1985-09-17 Cornell Research Foundation, Inc. Anti-juvenile hormones
GB1511187A (en) * 1976-04-02 1978-05-17 Beecham Group Ltd Chromans
US4391815A (en) * 1976-04-02 1983-07-05 Beecham Group Limited Cyanobenzano[b]pyrans
NZ183551A (en) * 1976-04-02 1978-09-20 Beecham Group Ltd Aminochromanols and pharmaceutical compositions containingthem
US4203895A (en) * 1978-04-14 1980-05-20 Warner-Lambert Company Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
EP0009912B1 (fr) * 1978-10-04 1983-06-22 Beecham Group Plc Dérivés de chromanol, procédé pour leur préparation et compositions pharmaceutiques les contenant
DE3064285D1 (en) * 1979-09-28 1983-08-25 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
EP0028064B1 (fr) * 1979-09-28 1983-07-20 Beecham Group Plc Dérivés du chromanol, procédé pour leur préparation et composition pharmaceutique les contenant
GB2064514B (en) * 1979-10-29 1984-01-18 Maruko Pharmaceutical Co Flavan compounds and acid addition salts thereof and pharmaceutical compositions thereof
EP0033613A1 (fr) * 1980-02-02 1981-08-12 Beecham Group Plc Dérivés du chromanol, procédé pour leur préparation et compositions les contenant
DE3163018D1 (en) 1980-02-02 1984-05-17 Beecham Group Plc Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them
DE3170604D1 (en) * 1980-08-21 1985-06-27 Beecham Group Plc Chromanol derivatives, their production and pharmaceutical compositions containing them
ZM7682A1 (en) * 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
EP0076075B1 (fr) * 1981-09-25 1986-11-20 Beecham Group Plc Dérivés de benzopyranes pharmacologiquement actifs
EP0091748B1 (fr) * 1982-04-08 1986-06-18 Beecham Group Plc Antihypertensifs benzopyranols
DE3368057D1 (en) * 1982-05-21 1987-01-15 Beecham Group Plc Pharmaceutically active aminobenzopyrans
JPS59110690A (ja) * 1982-12-16 1984-06-26 Dai Ichi Seiyaku Co Ltd ベンゾピラン誘導体
DE3479726D1 (de) * 1983-05-18 1989-10-19 Beecham Group Plc Benzopyran derivatives.
CA1308108C (fr) * 1987-10-27 1992-09-29 Dominick A. Quagliato Derives antihypertension benzopyrane
FR2637896B1 (fr) * 1988-10-17 1990-11-30 Adir Nouveaux derives de l'amino chromanol, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
GB8902118D0 (en) * 1989-02-01 1989-03-22 Beecham Group Plc Chemical process
US5239090A (en) * 1989-02-01 1993-08-24 Beecham Group P.L.C. Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates
GB8924373D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
WO1991012005A1 (fr) * 1990-02-06 1991-08-22 Pfizer Inc. Derives et analogues de 3-piperidino-4-hydroxychroman neuroprotecteurs
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
BR9408506A (pt) * 1994-01-31 1997-08-05 Pfizer Compostos neuroprotetores
WO1997023209A1 (fr) * 1995-12-25 1997-07-03 Nissan Chemical Industries, Ltd. Agent therapeutique contre l'insuffisance cardiaque
CZ24499A3 (cs) 1996-07-26 1999-05-12 Nissan Chemical Industries, Ltd. Derivát chromanu a farmaceutický prostředek, který ho obsahuje

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518273A (en) * 1966-08-03 1970-06-30 Warner Lambert Pharmaceutical Benzopyranquinolinol derivatives and process for their production
US3704323A (en) * 1969-12-23 1972-11-28 Squibb & Sons Inc Indane derivatives
US3743659A (en) * 1971-08-25 1973-07-03 Riker Laboratories Inc Substituted isochromans and processes therefor

Also Published As

Publication number Publication date
ZA753076B (en) 1976-05-26
FR2272659A1 (fr) 1975-12-26
MY8100356A (en) 1981-12-31
JPS6160077B2 (fr) 1986-12-19
IE41539B1 (en) 1980-01-30
GB1495526A (en) 1977-12-21
DE2523281A1 (de) 1975-12-11
BE829611A (fr) 1975-11-28
ES438072A1 (es) 1977-01-16
JPS511477A (fr) 1976-01-08
AU8169375A (en) 1976-12-02
DK244875A (da) 1975-12-01
CA1072090A (fr) 1980-02-19
JPS6044308B2 (ja) 1985-10-02
US4048317A (en) 1977-09-13
KE3124A (en) 1981-05-15
IE41539L (en) 1975-11-30
HK20781A (en) 1981-05-22
NL7506421A (nl) 1975-12-02
JPS60231681A (ja) 1985-11-18

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Legal Events

Date Code Title Description
ST Notification of lapse