FR2265373A1 - Pyridyl alkyl-amidine derivs - hypoglycemics which influence flat metabolism for use in diabetes, hyperlipemia and adiposis - Google Patents
Pyridyl alkyl-amidine derivs - hypoglycemics which influence flat metabolism for use in diabetes, hyperlipemia and adiposisInfo
- Publication number
- FR2265373A1 FR2265373A1 FR7509945A FR7509945A FR2265373A1 FR 2265373 A1 FR2265373 A1 FR 2265373A1 FR 7509945 A FR7509945 A FR 7509945A FR 7509945 A FR7509945 A FR 7509945A FR 2265373 A1 FR2265373 A1 FR 2265373A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- hypoglycemics
- adiposis
- hyperlipemia
- diabetes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 239000003472 antidiabetic agent Substances 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 201000005577 familial hyperlipidemia Diseases 0.000 title abstract 2
- 229940126904 hypoglycaemic agent Drugs 0.000 title abstract 2
- 230000002218 hypoglycaemic effect Effects 0.000 title abstract 2
- 230000004060 metabolic process Effects 0.000 title abstract 2
- 125000004076 pyridyl group Chemical group 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003925 fat Substances 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2415063A DE2415063A1 (de) | 1974-03-28 | 1974-03-28 | Pyridylalkylamidine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE19742447258 DE2447258A1 (de) | 1974-10-03 | 1974-10-03 | Pyridylalkylamidine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2265373A1 true FR2265373A1 (en) | 1975-10-24 |
Family
ID=25766897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7509945A Withdrawn FR2265373A1 (en) | 1974-03-28 | 1975-03-28 | Pyridyl alkyl-amidine derivs - hypoglycemics which influence flat metabolism for use in diabetes, hyperlipemia and adiposis |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS50129721A (enExample) |
| DK (1) | DK133775A (enExample) |
| FI (1) | FI750906A7 (enExample) |
| FR (1) | FR2265373A1 (enExample) |
| IL (1) | IL46914A0 (enExample) |
| NL (1) | NL7503743A (enExample) |
| NO (1) | NO750876L (enExample) |
| SE (1) | SE7503550L (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100603172B1 (ko) * | 1998-02-19 | 2006-07-24 | 바이엘 크롭사이언스 리미티드 | 살균제로서 유용한 2-피리딜메틸아민 유도체 |
| WO2010077586A1 (en) * | 2008-12-08 | 2010-07-08 | Allergan, Inc. | N-(1-phenyl-2-arylethyl)-4,5-dihydro-3h-pyrrol-2-amine compounds as subtype selective modulators of alpha2b or alpha2b and alpha2c adrenoceptors |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2240468T3 (da) * | 2008-01-18 | 2014-01-20 | Allergan Inc | Selektive adrenerge stoffer af undertype alpha 2 og fremgangsmåder til fremstilling heraf |
-
1975
- 1975-03-14 NO NO750876A patent/NO750876L/no unknown
- 1975-03-25 IL IL46914A patent/IL46914A0/xx unknown
- 1975-03-26 DK DK133775A patent/DK133775A/da unknown
- 1975-03-26 FI FI750906A patent/FI750906A7/fi not_active Application Discontinuation
- 1975-03-26 JP JP50035648A patent/JPS50129721A/ja active Pending
- 1975-03-26 SE SE7503550A patent/SE7503550L/xx not_active Application Discontinuation
- 1975-03-27 NL NL7503743A patent/NL7503743A/xx unknown
- 1975-03-28 FR FR7509945A patent/FR2265373A1/fr not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100603172B1 (ko) * | 1998-02-19 | 2006-07-24 | 바이엘 크롭사이언스 리미티드 | 살균제로서 유용한 2-피리딜메틸아민 유도체 |
| EP1056723B1 (en) * | 1998-02-19 | 2007-11-28 | Bayer CropScience Limited | 2-pyridylmethylamine derivatives useful as fungicides |
| WO2010077586A1 (en) * | 2008-12-08 | 2010-07-08 | Allergan, Inc. | N-(1-phenyl-2-arylethyl)-4,5-dihydro-3h-pyrrol-2-amine compounds as subtype selective modulators of alpha2b or alpha2b and alpha2c adrenoceptors |
| US8183414B2 (en) | 2008-12-08 | 2012-05-22 | Allergan, Inc. | N-(1-phenyl-2-arylethyl)-4,5-dihydro-2H-pyrrol-5-amine compounds as subtype selective modulators of ALPHA2B or ALPHA2B and ALPHA2C adrenoceptors |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7503743A (nl) | 1975-09-30 |
| FI750906A7 (enExample) | 1975-09-29 |
| SE7503550L (enExample) | 1975-09-29 |
| NO750876L (enExample) | 1975-09-30 |
| IL46914A0 (en) | 1975-05-22 |
| DK133775A (enExample) | 1975-09-29 |
| JPS50129721A (enExample) | 1975-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |