FR2264525A1 - - Google Patents

Info

Publication number
FR2264525A1
FR2264525A1 FR7409963A FR7409963A FR2264525A1 FR 2264525 A1 FR2264525 A1 FR 2264525A1 FR 7409963 A FR7409963 A FR 7409963A FR 7409963 A FR7409963 A FR 7409963A FR 2264525 A1 FR2264525 A1 FR 2264525A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7409963A
Other languages
French (fr)
Other versions
FR2264525B1 (xx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EXPL MARQUES BREVETS ET
Original Assignee
EXPL MARQUES BREVETS ET
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EXPL MARQUES BREVETS ET filed Critical EXPL MARQUES BREVETS ET
Priority to FR7409963A priority Critical patent/FR2264525B1/fr
Priority to DE2511576A priority patent/DE2511576C2/de
Priority to LU72102A priority patent/LU72102A1/xx
Priority to CA222,798A priority patent/CA1062280A/fr
Priority to ES435898A priority patent/ES435898A1/es
Priority to CH362775A priority patent/CH609669A5/xx
Priority to AT217875A priority patent/AT346856B/de
Priority to BE154602A priority patent/BE826999A/xx
Priority to GB1199975A priority patent/GB1462316A/en
Priority to JP3484475A priority patent/JPS5526134B2/ja
Priority to NLAANVRAGE7503515,A priority patent/NL169461C/xx
Publication of FR2264525A1 publication Critical patent/FR2264525A1/fr
Priority to US05/751,964 priority patent/US4080472A/en
Application granted granted Critical
Publication of FR2264525B1 publication Critical patent/FR2264525B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7409963A 1974-03-22 1974-03-22 Expired FR2264525B1 (xx)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR7409963A FR2264525B1 (xx) 1974-03-22 1974-03-22
DE2511576A DE2511576C2 (de) 1974-03-22 1975-03-17 Metformin-clofibrat, Verfahren zu seiner Herstellung und dieses enthaltendes Arzneimittel
LU72102A LU72102A1 (xx) 1974-03-22 1975-03-20
ES435898A ES435898A1 (es) 1974-03-22 1975-03-21 Un procedimiento de preparacion de clofibrato de metformi- na.
CH362775A CH609669A5 (en) 1974-03-22 1975-03-21 Process for the preparation of metformin clofibrate
AT217875A AT346856B (de) 1974-03-22 1975-03-21 Verfahren zur herstellung des neuen 1,1- dimethylbiguanidsalzes der 2-p-chlorphenoxy-2-methylpropionsaeure
CA222,798A CA1062280A (fr) 1974-03-22 1975-03-21 Procede de preparation de clofibrate de metformine
BE154602A BE826999A (fr) 1974-03-22 1975-03-21 Clofibrate de metformine
GB1199975A GB1462316A (en) 1974-03-22 1975-03-21 Clofibric acid salt
JP3484475A JPS5526134B2 (xx) 1974-03-22 1975-03-22
NLAANVRAGE7503515,A NL169461C (nl) 1974-03-22 1975-03-24 Werkwijze voor de bereiding van een geneesmiddel, gevormd geneesmiddel en werkwijze voor de bereiding van een zout van clofibrinezuur met een biguanideverbinding.
US05/751,964 US4080472A (en) 1974-03-22 1976-12-17 Metformin 2-(p-chlorophenoxy)-2-methylpropionate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7409963A FR2264525B1 (xx) 1974-03-22 1974-03-22

Publications (2)

Publication Number Publication Date
FR2264525A1 true FR2264525A1 (xx) 1975-10-17
FR2264525B1 FR2264525B1 (xx) 1977-11-04

Family

ID=9136732

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7409963A Expired FR2264525B1 (xx) 1974-03-22 1974-03-22

Country Status (11)

Country Link
JP (1) JPS5526134B2 (xx)
AT (1) AT346856B (xx)
BE (1) BE826999A (xx)
CA (1) CA1062280A (xx)
CH (1) CH609669A5 (xx)
DE (1) DE2511576C2 (xx)
ES (1) ES435898A1 (xx)
FR (1) FR2264525B1 (xx)
GB (1) GB1462316A (xx)
LU (1) LU72102A1 (xx)
NL (1) NL169461C (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774591A1 (fr) * 1998-02-12 1999-08-13 Lipha Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie
FR2796551A1 (fr) * 1999-07-23 2001-01-26 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
FR2796940A1 (fr) * 1999-07-26 2001-02-02 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60196425A (ja) * 1984-03-16 1985-10-04 Daido Metal Kogyo Kk 軸受すきまを一定に維持されたパツド型ジヤ−ナル軸受装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7116M (xx) * 1968-01-08 1969-07-15
AT317235B (de) * 1972-08-22 1974-08-26 Hurka Wilhelm Verfahren zur Herstellung des neuen 2-(p-Chlorphenoxy)-2-methylpropionsäuresalzes des 1-Phenäthylbiguanids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774591A1 (fr) * 1998-02-12 1999-08-13 Lipha Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie
WO1999040904A2 (en) * 1998-02-12 1999-08-19 Merck Patent Gmbh Pharmaceutical composition comprising a combination of metformin and fibrate, and its use for the treatment of hyperglycemia
WO1999040904A3 (en) * 1998-02-12 1999-09-30 Merck Patent Gmbh Pharmaceutical composition comprising a combination of metformin and fibrate, and its use for the treatment of hyperglycemia
US6372790B1 (en) 1998-02-12 2002-04-16 Merck Patent Gesellschaft Mit Beschrankter Haftung Pharmaceutical composition comprising a combination of metformin and fibrate, and its use for the preparation of medicines intended to reduce hyperglycaemia
FR2796551A1 (fr) * 1999-07-23 2001-01-26 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
FR2796940A1 (fr) * 1999-07-26 2001-02-02 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant

Also Published As

Publication number Publication date
NL7503515A (nl) 1975-09-24
GB1462316A (en) 1977-01-26
DE2511576A1 (de) 1975-09-25
NL169461B (nl) 1982-02-16
ES435898A1 (es) 1976-12-16
CH609669A5 (en) 1979-03-15
CA1062280A (fr) 1979-09-11
DE2511576C2 (de) 1983-07-07
FR2264525B1 (xx) 1977-11-04
NL169461C (nl) 1982-07-16
LU72102A1 (xx) 1975-08-20
ATA217875A (de) 1978-04-15
JPS5526134B2 (xx) 1980-07-11
BE826999A (fr) 1975-07-16
JPS50135043A (xx) 1975-10-25
AT346856B (de) 1978-11-27

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property