FR2230374A1 - Phosphonates contg. a P-32 or P-33 radionuclide - prepd. by reaction of labelled phosphorus trichloride and acid - Google Patents
Phosphonates contg. a P-32 or P-33 radionuclide - prepd. by reaction of labelled phosphorus trichloride and acidInfo
- Publication number
- FR2230374A1 FR2230374A1 FR7417965A FR7417965A FR2230374A1 FR 2230374 A1 FR2230374 A1 FR 2230374A1 FR 7417965 A FR7417965 A FR 7417965A FR 7417965 A FR7417965 A FR 7417965A FR 2230374 A1 FR2230374 A1 FR 2230374A1
- Authority
- FR
- France
- Prior art keywords
- cpds
- tumours
- labelled
- contg
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- FAIAAWCVCHQXDN-UHFFFAOYSA-N phosphorus trichloride Chemical compound ClP(Cl)Cl FAIAAWCVCHQXDN-UHFFFAOYSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 4
- 229910018828 PO3H2 Inorganic materials 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 210000004872 soft tissue Anatomy 0.000 abstract 2
- 206010005949 Bone cancer Diseases 0.000 abstract 1
- -1 amino, carboxymethyl Chemical group 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 125000000286 phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36297173A | 1973-05-23 | 1973-05-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2230374A1 true FR2230374A1 (en) | 1974-12-20 |
| FR2230374B1 FR2230374B1 (xx) | 1978-07-21 |
Family
ID=23428261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7417965A Granted FR2230374A1 (en) | 1973-05-23 | 1974-05-22 | Phosphonates contg. a P-32 or P-33 radionuclide - prepd. by reaction of labelled phosphorus trichloride and acid |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE815397A (xx) |
| DE (1) | DE2424453C3 (xx) |
| FR (1) | FR2230374A1 (xx) |
| NL (1) | NL7406952A (xx) |
| PH (1) | PH12898A (xx) |
| ZA (1) | ZA743159B (xx) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000076556A2 (en) * | 1999-06-11 | 2000-12-21 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
| EP1426063A3 (en) * | 2000-02-18 | 2004-07-14 | Civatech Corporation | Brachytherapy seeds and stents that can be activated by neutron rays |
| US7118729B1 (en) | 1999-07-12 | 2006-10-10 | Civatech Corporation | Radioactive source materials formable into various shapes |
| US7686756B2 (en) | 2006-08-29 | 2010-03-30 | Ciratech Oncology | Brachytherapy devices and related methods and computer program products |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7094885B2 (en) | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
-
1974
- 1974-05-10 PH PH15822A patent/PH12898A/en unknown
- 1974-05-17 ZA ZA00743159A patent/ZA743159B/xx unknown
- 1974-05-20 DE DE2424453A patent/DE2424453C3/de not_active Expired
- 1974-05-22 FR FR7417965A patent/FR2230374A1/fr active Granted
- 1974-05-22 BE BE144624A patent/BE815397A/xx unknown
- 1974-05-22 NL NL7406952A patent/NL7406952A/xx not_active Application Discontinuation
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000076556A2 (en) * | 1999-06-11 | 2000-12-21 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
| WO2000076556A3 (en) * | 1999-07-11 | 2001-10-11 | Neorx Corp | High dose radionuclide complexes for bone marrow suppression |
| US7118729B1 (en) | 1999-07-12 | 2006-10-10 | Civatech Corporation | Radioactive source materials formable into various shapes |
| US8012455B2 (en) | 1999-07-12 | 2011-09-06 | Civatech Corporation | Radioactive source materials formable into various shapes |
| EP1426063A3 (en) * | 2000-02-18 | 2004-07-14 | Civatech Corporation | Brachytherapy seeds and stents that can be activated by neutron rays |
| US7686756B2 (en) | 2006-08-29 | 2010-03-30 | Ciratech Oncology | Brachytherapy devices and related methods and computer program products |
| US9358377B2 (en) | 2006-08-29 | 2016-06-07 | Civatech Onocology | Brachytherapy devices and related methods and computer program products |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2424453B2 (de) | 1980-06-12 |
| NL7406952A (xx) | 1974-11-26 |
| ZA743159B (en) | 1975-05-28 |
| PH12898A (en) | 1979-10-04 |
| DE2424453A1 (de) | 1974-12-12 |
| FR2230374B1 (xx) | 1978-07-21 |
| DE2424453C3 (de) | 1981-02-26 |
| BE815397A (fr) | 1974-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |