FR2014048A1 - Substd 6,7-dihydro and 2,3,6,7-tetrahydro-5h thiazolo - (3 2a)-pyrimidines and their salts - Google Patents

Substd 6,7-dihydro and 2,3,6,7-tetrahydro-5h thiazolo - (3 2a)-pyrimidines and their salts

Info

Publication number
FR2014048A1
FR2014048A1 FR6925918A FR6925918A FR2014048A1 FR 2014048 A1 FR2014048 A1 FR 2014048A1 FR 6925918 A FR6925918 A FR 6925918A FR 6925918 A FR6925918 A FR 6925918A FR 2014048 A1 FR2014048 A1 FR 2014048A1
Authority
FR
France
Prior art keywords
substd
thiazolo
pyrimidines
tetrahydro
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6925918A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2014048A1 publication Critical patent/FR2014048A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Purses, Travelling Bags, Baskets, Or Suitcases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Substd 6,7-dihydro-and 2,36,7-tetrahydro-SH-thiazolo (3,2a)-pyrimidines and their salts. N3A. Compounds of formula (I): (where R2, R3 and r4 = H, Cl, or F, but at least one must be Cl or F; R1 = Cl-4C alkyl; n = 2-3, A = H and B = OH or A+B form a C=C bond). Preferred are (I) and (II) with R1 = Me or Et, R3 = Cl, R2 = R4 = H, and n = 2., esp. those where A = H and B = OH. Used as (a) Anoretics and antidepressants (dose: 35-300 mg. (n=3); 15-150 mg. (n=2) and diuretics (n=z) Dose : 50-500 mg. Preparation is, e.g. as follows:- X = Br or Cl.
FR6925918A 1968-07-31 1969-07-29 Substd 6,7-dihydro and 2,3,6,7-tetrahydro-5h thiazolo - (3 2a)-pyrimidines and their salts Withdrawn FR2014048A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74892968A 1968-07-31 1968-07-31
US74893468A 1968-07-31 1968-07-31
US79045169A 1969-01-10 1969-01-10
US79044969A 1969-01-10 1969-01-10

Publications (1)

Publication Number Publication Date
FR2014048A1 true FR2014048A1 (en) 1970-04-10

Family

ID=27505649

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6925918A Withdrawn FR2014048A1 (en) 1968-07-31 1969-07-29 Substd 6,7-dihydro and 2,3,6,7-tetrahydro-5h thiazolo - (3 2a)-pyrimidines and their salts

Country Status (9)

Country Link
BE (1) BE736739A (en)
CH (1) CH513918A (en)
DE (1) DE1938674A1 (en)
FR (1) FR2014048A1 (en)
IL (1) IL32724A0 (en)
NL (1) NL6911687A (en)
NO (1) NO126229B (en)
OA (1) OA03392A (en)
RO (1) RO56851A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2282882A1 (en) * 1974-07-27 1976-03-26 Hoechst Ag THIAZOLIDINE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS
FR2414510A1 (en) * 1977-06-27 1979-08-10 Parcor Hypotensive condensed thiazole(s) - for treating all stages of arterial hypertension
FR2448544A1 (en) * 1979-02-12 1980-09-05 Synthelabo THIAZOLE DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
FR2479831A1 (en) * 1980-04-08 1981-10-09 Synthelabo THIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2508909A1 (en) * 1981-07-03 1983-01-07 Synthelabo PHENETHYL DERIVATIVES OF THIAZOLE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10112197A1 (en) * 2001-03-14 2002-09-19 Gruenenthal Gmbh Medicaments for treating e.g. epilepsy, schizophrenia, neurodegenerative diseases or especially pain, comprising new or known pyrazolo-pyrimidine or thiazolo-pyrimidine compounds
TW200639177A (en) * 2005-02-08 2006-11-16 Prosidion Ltd Dihydroimidazothiazole derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2969369A (en) * 1959-10-23 1961-01-24 Searle & Co Derivatives of 3-phenyl-5, 6-dihydroimidazo-[2. 1-b] thiazoles

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2969369A (en) * 1959-10-23 1961-01-24 Searle & Co Derivatives of 3-phenyl-5, 6-dihydroimidazo-[2. 1-b] thiazoles

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2282882A1 (en) * 1974-07-27 1976-03-26 Hoechst Ag THIAZOLIDINE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS
FR2414510A1 (en) * 1977-06-27 1979-08-10 Parcor Hypotensive condensed thiazole(s) - for treating all stages of arterial hypertension
FR2448544A1 (en) * 1979-02-12 1980-09-05 Synthelabo THIAZOLE DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
EP0015798A1 (en) * 1979-02-12 1980-09-17 Synthelabo Thiazole derivatives, their preparation and medicaments containing them
FR2479831A1 (en) * 1980-04-08 1981-10-09 Synthelabo THIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP0038731A2 (en) * 1980-04-08 1981-10-28 Synthelabo Thiazole derivatives, their preparation and use in therapeutics
EP0038731A3 (en) * 1980-04-08 1981-11-04 Synthelabo Thiazole derivatives, their preparation and use in therapeutics
FR2508909A1 (en) * 1981-07-03 1983-01-07 Synthelabo PHENETHYL DERIVATIVES OF THIAZOLE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP0069623A1 (en) * 1981-07-03 1983-01-12 Synthelabo Phenylethylthiazole derivatives, their preparation and their therapeutical use

Also Published As

Publication number Publication date
NL6911687A (en) 1970-02-03
DE1938674A1 (en) 1970-02-05
CH513918A (en) 1971-10-15
RO56851A (en) 1974-11-11
OA03392A (en) 1970-12-15
NO126229B (en) 1973-01-08
BE736739A (en) 1970-01-29
IL32724A0 (en) 1969-09-25

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