FR2228475A1 - - Google Patents

Info

Publication number
FR2228475A1
FR2228475A1 FR7415681A FR7415681A FR2228475A1 FR 2228475 A1 FR2228475 A1 FR 2228475A1 FR 7415681 A FR7415681 A FR 7415681A FR 7415681 A FR7415681 A FR 7415681A FR 2228475 A1 FR2228475 A1 FR 2228475A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7415681A
Other versions
FR2228475B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of FR2228475A1 publication Critical patent/FR2228475A1/fr
Application granted granted Critical
Publication of FR2228475B1 publication Critical patent/FR2228475B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7415681A 1973-05-07 1974-05-07 Expired FR2228475B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/357,763 US4007173A (en) 1973-05-07 1973-05-07 α-amino-α-(ureidophenyl)acetamidocephalosporins

Publications (2)

Publication Number Publication Date
FR2228475A1 true FR2228475A1 (fr) 1974-12-06
FR2228475B1 FR2228475B1 (fr) 1978-07-28

Family

ID=23406931

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7415681A Expired FR2228475B1 (fr) 1973-05-07 1974-05-07
FR7535593A Granted FR2299318A1 (fr) 1973-05-07 1975-11-21 Nouveaux derives de l'acide a-amino phenyl acetique

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7535593A Granted FR2299318A1 (fr) 1973-05-07 1975-11-21 Nouveaux derives de l'acide a-amino phenyl acetique

Country Status (22)

Country Link
US (5) US4007173A (fr)
JP (1) JPS5013391A (fr)
AR (1) AR206315A1 (fr)
AT (1) AT329753B (fr)
AU (1) AU475779B2 (fr)
BE (1) BE814546A (fr)
CA (1) CA1041085A (fr)
CH (1) CH595389A5 (fr)
CS (1) CS181264B2 (fr)
DD (1) DD114267A5 (fr)
DE (1) DE2422068A1 (fr)
ES (1) ES426003A1 (fr)
FR (2) FR2228475B1 (fr)
GB (2) GB1456144A (fr)
HU (1) HU168312B (fr)
IE (1) IE39549B1 (fr)
IL (1) IL44680A (fr)
IN (1) IN141295B (fr)
LU (1) LU69997A1 (fr)
NL (1) NL7405990A (fr)
SE (1) SE430506B (fr)
ZA (1) ZA742353B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000500A2 (fr) * 1977-07-18 1979-02-07 Ciba-Geigy Ag Dérivés de, cephalosporine leur préparation et leurs compositions pharmaceutiques

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5716116B2 (fr) * 1974-02-08 1982-04-02
US4060610A (en) 1974-12-27 1977-11-29 Smithkline Corporation Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections
US3989694A (en) 1974-12-27 1976-11-02 Smithkline Corporation 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins
US4286089A (en) 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4080451A (en) * 1975-03-27 1978-03-21 Pfizer Inc. Cephalosporin derivatives
US4183925A (en) * 1975-03-27 1980-01-15 Pfizer Inc. 7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use
US4254273A (en) * 1975-06-11 1981-03-03 Merck & Co., Inc. Process for preparing esters of α-methyl-3,4-dihydroxyphenylalanine
US4220644A (en) 1976-05-03 1980-09-02 Smithkline Corporation 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
GB1579532A (en) * 1976-05-21 1980-11-19 Farmaceutici Italia Cephalosporins
US4236001A (en) * 1976-12-01 1980-11-25 Smithkline Corporation 7β-Acyloxy-3-heterocyclicthiomethyl cephalosporins
LU77786A1 (de) * 1977-07-15 1979-03-26 Ciba Geigy Ag Verfahren zur herstellung neuer benzopyranderivate
US4313945A (en) * 1978-11-23 1982-02-02 Ciba-Geigy Corporation 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
US5256405A (en) * 1991-12-30 1993-10-26 Tom's Of Maine Herbal deodorant
AU2629795A (en) * 1994-12-12 1996-07-03 Chugai Seiyaku Kabushiki Kaisha Aniline derivative having the effect of inhibiting nitrogen monoxide synthase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341531A (en) * 1967-02-15 1967-09-12 American Cyanamid Co Substituted 7-acetylamino cephalosporanic acids
US3464985A (en) * 1967-08-18 1969-09-02 Bristol Myers Co 7 - (d - alpha - amino - (acetamidophenylacetamido))-cephalosporanic acids and derivatives thereof
US3573295A (en) * 1968-07-01 1971-03-30 Bristol Myers Co Process for the preparation of 7-aminocephalosporanic acid
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3634418A (en) * 1969-08-20 1972-01-11 Bristol Myers Co 3 - azidomethyl - 7-(alpha-aminophenyl(or thienyl)acetamido)ceph - 3 -em-4-oic acids
US3692779A (en) * 1970-08-12 1972-09-19 Bristol Myers Co 7-{8 n-(substituted-imidoyl)aminoacetamide{9 cephalosporanic acids and derivatives thereof
US3855213A (en) * 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
US3704297A (en) * 1971-03-05 1972-11-28 American Home Prod 7 - (1,4 - cyclohexadienylacylamido)cephalosporanic acids and related compounds
US3813376A (en) * 1972-08-31 1974-05-28 Bristol Myers Co 7-(o-aminomethylphenyl-acetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
AR205537A1 (es) * 1973-05-10 1976-05-14 Fujisawa Pharmaceutical Co Procedimiento para la preparacion de derivados de acido 7-substituido fenilglicinamido - 3 - substituido - 3 - cefem - 4 - carboxilicos

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000500A2 (fr) * 1977-07-18 1979-02-07 Ciba-Geigy Ag Dérivés de, cephalosporine leur préparation et leurs compositions pharmaceutiques
EP0000500A3 (en) * 1977-07-18 1979-06-27 Ciba-Geigy Ag Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS5013391A (fr) 1975-02-12
NL7405990A (fr) 1974-11-11
ATA369374A (de) 1975-08-15
IE39549L (en) 1974-11-07
CH595389A5 (fr) 1978-02-15
AT329753B (de) 1976-05-25
BE814546A (fr) 1974-11-04
GB1456144A (en) 1976-11-17
FR2299318A1 (fr) 1976-08-27
LU69997A1 (fr) 1974-09-25
IL44680A0 (en) 1974-06-30
DE2422068A1 (de) 1974-11-28
HU168312B (fr) 1976-03-28
IE39549B1 (en) 1978-11-08
US4067978A (en) 1978-01-10
IN141295B (fr) 1977-02-12
IL44680A (en) 1977-03-31
DD114267A5 (fr) 1975-07-20
CS181264B2 (en) 1978-03-31
US4067976A (en) 1978-01-10
AU475779B2 (en) 1976-09-02
ES426003A1 (es) 1976-07-01
US4067977A (en) 1978-01-10
FR2299318B1 (fr) 1978-05-12
FR2228475B1 (fr) 1978-07-28
US4091227A (en) 1978-05-23
CA1041085A (fr) 1978-10-24
US4007173A (en) 1977-02-08
AU6865674A (en) 1975-11-06
AR206315A1 (es) 1976-07-15
ZA742353B (en) 1975-04-30
GB1456145A (en) 1976-11-17
SE430506B (sv) 1983-11-21

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Legal Events

Date Code Title Description
ST Notification of lapse