EP0000500A3 - Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them Download PDF

Info

Publication number
EP0000500A3
EP0000500A3 EP78100367A EP78100367A EP0000500A3 EP 0000500 A3 EP0000500 A3 EP 0000500A3 EP 78100367 A EP78100367 A EP 78100367A EP 78100367 A EP78100367 A EP 78100367A EP 0000500 A3 EP0000500 A3 EP 0000500A3
Authority
EP
European Patent Office
Prior art keywords
cephalosprin
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP78100367A
Other versions
EP0000500B1 (en
EP0000500A2 (en
Inventor
Karoly Dr. Kocsis
Peter Dr. Schneider
Bruno Dr. Fechtig
Riccardo Dr. Scartazzini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Priority to DE8080100097T priority Critical patent/DE3065568D1/en
Publication of EP0000500A2 publication Critical patent/EP0000500A2/en
Publication of EP0000500A3 publication Critical patent/EP0000500A3/en
Application granted granted Critical
Publication of EP0000500B1 publication Critical patent/EP0000500B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP78100367A 1977-07-18 1978-07-11 Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them Expired EP0000500B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE8080100097T DE3065568D1 (en) 1977-07-18 1978-07-11 Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77788 1977-07-18
LU77788 1977-07-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP80100097.7 Division-Into 1978-07-11

Publications (3)

Publication Number Publication Date
EP0000500A2 EP0000500A2 (en) 1979-02-07
EP0000500A3 true EP0000500A3 (en) 1979-06-27
EP0000500B1 EP0000500B1 (en) 1982-04-28

Family

ID=19728643

Family Applications (2)

Application Number Title Priority Date Filing Date
EP78100367A Expired EP0000500B1 (en) 1977-07-18 1978-07-11 Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them
EP80100097A Expired EP0016900B1 (en) 1977-07-18 1978-07-11 Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP80100097A Expired EP0016900B1 (en) 1977-07-18 1978-07-11 Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use

Country Status (14)

Country Link
US (1) US4467101A (en)
EP (2) EP0000500B1 (en)
JP (1) JPS5452094A (en)
AT (1) AT361621B (en)
AU (1) AU522514B2 (en)
CA (1) CA1113453A (en)
DE (2) DE2861767D1 (en)
DK (1) DK319178A (en)
ES (1) ES471812A1 (en)
IE (1) IE47032B1 (en)
IL (1) IL55152A (en)
IT (1) IT7850324A0 (en)
NZ (1) NZ187852A (en)
ZA (1) ZA784050B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4313945A (en) * 1978-11-23 1982-02-02 Ciba-Geigy Corporation 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping
US4464366A (en) * 1979-12-19 1984-08-07 Ciba Geigy Corporation Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group
EP0059683A3 (en) * 1981-02-27 1982-12-01 Ciba-Geigy Ag 7-acylamido-3-cephem-4-carboxylic acids, process for their preparation, pharmaceutical compositions containing them and their use
US4751299A (en) * 1983-11-18 1988-06-14 Takeda Chemical Industries, Ltd. Optically active β-lactams and method of their production
GB2167434B (en) * 1984-11-20 1988-09-14 Witton Chem Co Ltd Dispersing agents for coal slurries
WO2008157288A2 (en) 2007-06-13 2008-12-24 Wayne State University Board Of Governors A baclofen solution for low-volume therapeutic delivery
US20100210604A1 (en) * 2007-06-13 2010-08-19 Meythaler Jay M Zwitterion solution for low-volume therapeutic delivery

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2228475A1 (en) * 1973-05-07 1974-12-06 Smithkline Corp
FR2228476A1 (en) * 1973-05-10 1974-12-06 Fujisawa Pharmaceutical Co
FR2235695A1 (en) * 1973-07-06 1975-01-31 Fujisawa Pharmaceutical Co

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919206A (en) * 1973-09-25 1975-11-11 Yeda Res & Dev 7-(Halomethylaryl)acetamidocephalosporin derivatives
US3929778A (en) * 1974-08-08 1975-12-30 Squibb & Sons Inc {8 (Acylcarbamoyl) thioacetyl{9 {0 cephalosporin derivatives
LU77786A1 (en) * 1977-07-15 1979-03-26 Ciba Geigy Ag METHOD FOR PRODUCING NEW BENZOPYRANE DERIVATIVES

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2228475A1 (en) * 1973-05-07 1974-12-06 Smithkline Corp
FR2228476A1 (en) * 1973-05-10 1974-12-06 Fujisawa Pharmaceutical Co
FR2235695A1 (en) * 1973-07-06 1975-01-31 Fujisawa Pharmaceutical Co

Also Published As

Publication number Publication date
CA1113453A (en) 1981-12-01
IE781431L (en) 1979-01-18
DK319178A (en) 1979-01-19
AU522514B2 (en) 1982-06-10
AT361621B (en) 1981-03-25
EP0016900A1 (en) 1980-10-15
EP0000500B1 (en) 1982-04-28
EP0000500A2 (en) 1979-02-07
NZ187852A (en) 1981-03-16
ATA515678A (en) 1980-08-15
AU3806578A (en) 1980-01-17
DE2861767D1 (en) 1982-06-09
IT7850324A0 (en) 1978-07-17
ZA784050B (en) 1979-08-29
IL55152A (en) 1982-07-30
IE47032B1 (en) 1983-11-30
JPS5452094A (en) 1979-04-24
IL55152A0 (en) 1978-09-29
US4467101A (en) 1984-08-21
EP0016900B1 (en) 1983-11-16
ES471812A1 (en) 1979-10-16
DE3065568D1 (en) 1983-12-22

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