FR2186241A1 - 2-(3-trifluoromethylanilino)-benzoic and -nicotinic acid esters - with anti-inflammatory, analgesic activity - Google Patents
2-(3-trifluoromethylanilino)-benzoic and -nicotinic acid esters - with anti-inflammatory, analgesic activityInfo
- Publication number
- FR2186241A1 FR2186241A1 FR7219116A FR7219116A FR2186241A1 FR 2186241 A1 FR2186241 A1 FR 2186241A1 FR 7219116 A FR7219116 A FR 7219116A FR 7219116 A FR7219116 A FR 7219116A FR 2186241 A1 FR2186241 A1 FR 2186241A1
- Authority
- FR
- France
- Prior art keywords
- benzoic
- nicotinic acid
- trifluoromethylanilino
- inflammatory
- acid esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000202 analgesic effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000001348 alkyl chlorides Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- LPEPZBJOKDYZAD-UHFFFAOYSA-N flufenamic acid Chemical compound OC(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1 LPEPZBJOKDYZAD-UHFFFAOYSA-N 0.000 abstract 1
- 229960004369 flufenamic acid Drugs 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000002085 irritant Substances 0.000 abstract 1
- 231100000021 irritant Toxicity 0.000 abstract 1
- 231100001231 less toxic Toxicity 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7219116A FR2186241A1 (en) | 1972-05-29 | 1972-05-29 | 2-(3-trifluoromethylanilino)-benzoic and -nicotinic acid esters - with anti-inflammatory, analgesic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7219116A FR2186241A1 (en) | 1972-05-29 | 1972-05-29 | 2-(3-trifluoromethylanilino)-benzoic and -nicotinic acid esters - with anti-inflammatory, analgesic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2186241A1 true FR2186241A1 (en) | 1974-01-11 |
| FR2186241B1 FR2186241B1 (enExample) | 1975-10-17 |
Family
ID=9099231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7219116A Granted FR2186241A1 (en) | 1972-05-29 | 1972-05-29 | 2-(3-trifluoromethylanilino)-benzoic and -nicotinic acid esters - with anti-inflammatory, analgesic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2186241A1 (enExample) |
-
1972
- 1972-05-29 FR FR7219116A patent/FR2186241A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2186241B1 (enExample) | 1975-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |