FR2181709B1 - - Google Patents

Info

Publication number
FR2181709B1
FR2181709B1 FR7304280A FR7304280A FR2181709B1 FR 2181709 B1 FR2181709 B1 FR 2181709B1 FR 7304280 A FR7304280 A FR 7304280A FR 7304280 A FR7304280 A FR 7304280A FR 2181709 B1 FR2181709 B1 FR 2181709B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7304280A
Other languages
French (fr)
Other versions
FR2181709A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2181709A1 publication Critical patent/FR2181709A1/fr
Application granted granted Critical
Publication of FR2181709B1 publication Critical patent/FR2181709B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
FR7304280A 1972-02-07 1973-02-07 Expired FR2181709B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22429272A 1972-02-07 1972-02-07

Publications (2)

Publication Number Publication Date
FR2181709A1 FR2181709A1 (en) 1973-12-07
FR2181709B1 true FR2181709B1 (en) 1975-10-10

Family

ID=22840026

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7304280A Expired FR2181709B1 (en) 1972-02-07 1973-02-07

Country Status (15)

Country Link
JP (1) JPS4886880A (en)
KR (1) KR780000029B1 (en)
AR (1) AR195821A1 (en)
AT (1) AT323744B (en)
AU (1) AU5191873A (en)
BE (1) BE795023A (en)
DD (1) DD103644A5 (en)
DE (1) DE2303838C2 (en)
FR (1) FR2181709B1 (en)
GB (2) GB1388213A (en)
IE (1) IE37259B1 (en)
IL (1) IL41463A0 (en)
LU (1) LU66964A1 (en)
NL (1) NL7301650A (en)
ZA (1) ZA73137B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA738760B (en) * 1972-12-21 1974-08-28 Hoffmann La Roche Process for the manufacture of benzyl pyrimidines
GB1582245A (en) * 1976-06-09 1981-01-07 Wellcome Found Benzyl cyanoacetal derivatives and their conversion to pyrimidine derivatives
CA1084498A (en) * 1977-05-05 1980-08-26 Alexander E. Wick Benzylpyrimidines and process for the preparation thereof
LU77268A1 (en) * 1977-05-05 1979-01-18
DE2910510A1 (en) * 1979-03-16 1980-09-25 Heumann Ludwig & Co Gmbh 2,4-Di:amino-5-benzyl pyrimidine derivs. - are antibacterial cpds., prepd. by acylation of a 2,4-di:amino-5-(4'-hydroxy-benzyl) -pyrimidine cpd.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
FR1453056A (en) * 1964-11-12 1966-04-15 Hoffmann La Roche Process for the preparation of pyrimidine derivatives
DE1620729A1 (en) * 1965-07-08 1970-08-20 Wellcome Found Process for the preparation of substituted benzylpyrimidines
US3715433A (en) * 1969-06-02 1973-02-06 Hoffmann La Roche Growth promotion in swine

Also Published As

Publication number Publication date
ZA73137B (en) 1973-09-26
IE37259B1 (en) 1977-06-08
AU5191873A (en) 1974-08-08
NL7301650A (en) 1973-08-09
AT323744B (en) 1975-07-25
GB1388214A (en) 1975-03-26
JPS4886880A (en) 1973-11-15
LU66964A1 (en) 1974-09-25
FR2181709A1 (en) 1973-12-07
AR195821A1 (en) 1973-11-09
DE2303838C2 (en) 1982-09-23
IL41463A0 (en) 1973-04-30
DE2303838A1 (en) 1973-08-16
DD103644A5 (en) 1974-02-05
IE37259L (en) 1973-08-07
GB1388213A (en) 1975-03-26
KR780000029B1 (en) 1978-03-10
BE795023A (en) 1973-08-06

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Legal Events

Date Code Title Description
ST Notification of lapse