FR2180564A1 - Nitro-imidazole derivs - useful as trichomonacides and inters for trichomonacides - Google Patents
Nitro-imidazole derivs - useful as trichomonacides and inters for trichomonacidesInfo
- Publication number
- FR2180564A1 FR2180564A1 FR7214123A FR7214123A FR2180564A1 FR 2180564 A1 FR2180564 A1 FR 2180564A1 FR 7214123 A FR7214123 A FR 7214123A FR 7214123 A FR7214123 A FR 7214123A FR 2180564 A1 FR2180564 A1 FR 2180564A1
- Authority
- FR
- France
- Prior art keywords
- ch3co
- trichomonacides
- inters
- nitro
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- YZEUHQHUFTYLPH-UHFFFAOYSA-N 2-nitroimidazole Chemical compound [O-][N+](=O)C1=NC=CN1 YZEUHQHUFTYLPH-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003716 antitrichomonal agent Substances 0.000 title 2
- 125000004674 methylcarbonyl group Chemical group CC(=O)* 0.000 abstract 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 abstract 2
- FFYTTYVSDVWNMY-UHFFFAOYSA-N 2-Methyl-5-nitroimidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1 FFYTTYVSDVWNMY-UHFFFAOYSA-N 0.000 abstract 1
- 229960000583 acetic acid Drugs 0.000 abstract 1
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 230000001572 anti-trichomonad Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000012362 glacial acetic acid Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 abstract 1
- 229960000282 metronidazole Drugs 0.000 abstract 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical class OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 abstract 1
- 235000019260 propionic acid Nutrition 0.000 abstract 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000002963 trichomonacidal effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7214123A FR2180564A1 (en) | 1972-04-21 | 1972-04-21 | Nitro-imidazole derivs - useful as trichomonacides and inters for trichomonacides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7214123A FR2180564A1 (en) | 1972-04-21 | 1972-04-21 | Nitro-imidazole derivs - useful as trichomonacides and inters for trichomonacides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2180564A1 true FR2180564A1 (en) | 1973-11-30 |
| FR2180564B1 FR2180564B1 (enrdf_load_stackoverflow) | 1977-01-14 |
Family
ID=9097282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7214123A Granted FR2180564A1 (en) | 1972-04-21 | 1972-04-21 | Nitro-imidazole derivs - useful as trichomonacides and inters for trichomonacides |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2180564A1 (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2234003A1 (enrdf_load_stackoverflow) * | 1973-06-22 | 1975-01-17 | Janssen Pharmaceutica Nv |
-
1972
- 1972-04-21 FR FR7214123A patent/FR2180564A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2234003A1 (enrdf_load_stackoverflow) * | 1973-06-22 | 1975-01-17 | Janssen Pharmaceutica Nv |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2180564B1 (enrdf_load_stackoverflow) | 1977-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |