FR2178718A1 - 3-phenyl-3-(substd-amino)-3,4-dihydro-isocoumarins - and isochromans - as anti hypertensive agents and diuretics - Google Patents
3-phenyl-3-(substd-amino)-3,4-dihydro-isocoumarins - and isochromans - as anti hypertensive agents and diureticsInfo
- Publication number
- FR2178718A1 FR2178718A1 FR7211734A FR7211734A FR2178718A1 FR 2178718 A1 FR2178718 A1 FR 2178718A1 FR 7211734 A FR7211734 A FR 7211734A FR 7211734 A FR7211734 A FR 7211734A FR 2178718 A1 FR2178718 A1 FR 2178718A1
- Authority
- FR
- France
- Prior art keywords
- substd
- alkyl
- amino
- isochromans
- isocoumarins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940124538 antidiuretic agent Drugs 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
- 229940030600 antihypertensive agent Drugs 0.000 title 1
- 239000002934 diuretic Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- -1 morpholino, thiomorpholino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19722212674 DE2212674A1 (de) | 1972-03-16 | 1972-03-16 | Neue organische verbindungen und verfahren zu deren herstellung |
FR7211734A FR2178718A1 (en) | 1972-03-16 | 1972-04-04 | 3-phenyl-3-(substd-amino)-3,4-dihydro-isocoumarins - and isochromans - as anti hypertensive agents and diuretics |
BE781854A BE781854A (fr) | 1972-03-16 | 1972-04-07 | Nouveaux composes heterocycliques, leur preparation et leur applicationcomme medicaments |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19722212674 DE2212674A1 (de) | 1972-03-16 | 1972-03-16 | Neue organische verbindungen und verfahren zu deren herstellung |
FR7211734A FR2178718A1 (en) | 1972-03-16 | 1972-04-04 | 3-phenyl-3-(substd-amino)-3,4-dihydro-isocoumarins - and isochromans - as anti hypertensive agents and diuretics |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2178718A1 true FR2178718A1 (en) | 1973-11-16 |
FR2178718B1 FR2178718B1 (en, 2012) | 1975-08-01 |
Family
ID=25762901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7211734A Granted FR2178718A1 (en) | 1972-03-16 | 1972-04-04 | 3-phenyl-3-(substd-amino)-3,4-dihydro-isocoumarins - and isochromans - as anti hypertensive agents and diuretics |
Country Status (3)
Country | Link |
---|---|
BE (1) | BE781854A (en, 2012) |
DE (1) | DE2212674A1 (en, 2012) |
FR (1) | FR2178718A1 (en, 2012) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003104216A1 (en) * | 2002-06-10 | 2003-12-18 | Acadia Pharmaceuticals Inc. | Urotensin ii receptor modulators |
-
1972
- 1972-03-16 DE DE19722212674 patent/DE2212674A1/de active Pending
- 1972-04-04 FR FR7211734A patent/FR2178718A1/fr active Granted
- 1972-04-07 BE BE781854A patent/BE781854A/xx unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003104216A1 (en) * | 2002-06-10 | 2003-12-18 | Acadia Pharmaceuticals Inc. | Urotensin ii receptor modulators |
Also Published As
Publication number | Publication date |
---|---|
DE2212674A1 (de) | 1973-09-27 |
BE781854A (fr) | 1972-10-09 |
FR2178718B1 (en, 2012) | 1975-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |