FR2161776A1 - Aralkyl nicotinamides - hypocholesterolemics and anorexigenics - Google Patents

Aralkyl nicotinamides - hypocholesterolemics and anorexigenics

Info

Publication number
FR2161776A1
FR2161776A1 FR7142644A FR7142644A FR2161776A1 FR 2161776 A1 FR2161776 A1 FR 2161776A1 FR 7142644 A FR7142644 A FR 7142644A FR 7142644 A FR7142644 A FR 7142644A FR 2161776 A1 FR2161776 A1 FR 2161776A1
Authority
FR
France
Prior art keywords
hypocholesterolemics
anorexigenics
nicotinamides
aralkyl
aminopropane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7142644A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2161776A1 publication Critical patent/FR2161776A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/02—Treatment of water, waste water, or sewage by heating
    • C02F1/04—Treatment of water, waste water, or sewage by heating by distillation or evaporation
    • C02F1/10—Treatment of water, waste water, or sewage by heating by distillation or evaporation by direct contact with a particulate solid or with a fluid, as a heat transfer medium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hydrology & Water Resources (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental & Geological Engineering (AREA)
  • Water Supply & Treatment (AREA)
  • Pyridine Compounds (AREA)

Abstract

Compounds of formula (I) (where Z = divalent saturated straight or branched 1-5C hydrocarbon; X = H, halogen, lower alkyl or CF3; R = H or lower alkyl opt. substituted by Cl or CN; n = 0 or 1). Hypochlolesterolemics and anoretics. 136g. 1-phenyl-2-aminopropane and 101g. triethylamine in 3 litres benzene, were treated with 142g. nicotinoyl chloride. The mixt. was stirred for 30 mins. then heated under reflux for 30 minutes. The mixture was filtered hot, and the benzene evaporated. The residue was washed with hexane and dried to give N-(nicotinoyl)-1-phenyl-2-aminopropane.
FR7142644A 1971-11-22 1971-11-29 Aralkyl nicotinamides - hypocholesterolemics and anorexigenics Withdrawn FR2161776A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7141644A FR2233851A6 (en) 1971-11-22 1971-11-22

Publications (1)

Publication Number Publication Date
FR2161776A1 true FR2161776A1 (en) 1973-07-13

Family

ID=9086114

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7141644A Expired FR2233851A6 (en) 1971-11-10 1971-11-22
FR7142644A Withdrawn FR2161776A1 (en) 1971-11-22 1971-11-29 Aralkyl nicotinamides - hypocholesterolemics and anorexigenics

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7141644A Expired FR2233851A6 (en) 1971-11-10 1971-11-22

Country Status (1)

Country Link
FR (2) FR2233851A6 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004020414A1 (en) * 2002-08-28 2004-03-11 Pfizer Limited Oxytocin inhibitors
WO2017067784A1 (en) * 2015-10-23 2017-04-27 Basf Se Pyridine compounds for combating phytopathogenic fungi
US11064697B2 (en) 2015-07-24 2021-07-20 Basf Se Pyridine compounds useful for combating phytopathogenic fungi

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004020414A1 (en) * 2002-08-28 2004-03-11 Pfizer Limited Oxytocin inhibitors
US11064697B2 (en) 2015-07-24 2021-07-20 Basf Se Pyridine compounds useful for combating phytopathogenic fungi
WO2017067784A1 (en) * 2015-10-23 2017-04-27 Basf Se Pyridine compounds for combating phytopathogenic fungi
CN108349941A (en) * 2015-10-23 2018-07-31 巴斯夫欧洲公司 Prevent the pyridine compounds of plant pathogenic fungi

Also Published As

Publication number Publication date
FR2233851A6 (en) 1975-01-10

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Legal Events

Date Code Title Description
ST Notification of lapse