FR2145430A1 - 3-chloro-4-cyclohexyl-alphamethyl benzylamines - - antiinflammatory and analgesic agents - Google Patents
3-chloro-4-cyclohexyl-alphamethyl benzylamines - - antiinflammatory and analgesic agentsInfo
- Publication number
- FR2145430A1 FR2145430A1 FR7125902A FR7125902A FR2145430A1 FR 2145430 A1 FR2145430 A1 FR 2145430A1 FR 7125902 A FR7125902 A FR 7125902A FR 7125902 A FR7125902 A FR 7125902A FR 2145430 A1 FR2145430 A1 FR 2145430A1
- Authority
- FR
- France
- Prior art keywords
- chloro
- alphamethyl
- benzylamines
- antiinflammatory
- cyclohexyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ABBGBVAGXKUXGV-UHFFFAOYSA-N 1-(3-chloro-4-cyclohexylphenyl)ethanamine Chemical class ClC1=CC(C(N)C)=CC=C1C1CCCCC1 ABBGBVAGXKUXGV-UHFFFAOYSA-N 0.000 title 1
- 239000000730 antalgic agent Substances 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 238000010438 heat treatment Methods 0.000 abstract 2
- RKRJTJLDGZJTGZ-UHFFFAOYSA-N 2-(2-chlorocyclohexyl)-1-phenylethanone Chemical compound ClC1CCCCC1CC(=O)C1=CC=CC=C1 RKRJTJLDGZJTGZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- VZTDIZULWFCMLS-UHFFFAOYSA-N ammonium formate Chemical compound [NH4+].[O-]C=O VZTDIZULWFCMLS-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7125902A FR2145430A1 (en) | 1971-07-15 | 1971-07-15 | 3-chloro-4-cyclohexyl-alphamethyl benzylamines - - antiinflammatory and analgesic agents |
| BE774228A BE774228A (fr) | 1970-10-28 | 1971-10-20 | Nouveaux derives de 1'alpha-methylbenzylamine |
| GB4890371A GB1373544A (en) | 1970-10-28 | 1971-10-21 | Derivatives of alpha-methyl-benzyl-amine |
| US05/193,175 US4003931A (en) | 1970-10-28 | 1971-10-27 | Derivatives of alpha-methyl benzylamine |
| DE19712153535 DE2153535A1 (de) | 1970-10-28 | 1971-10-27 | Neue Derivate des alpha Methylbenzyl amins |
| CH1660871A CH545268A (fr) | 1971-07-15 | 1971-11-16 | Procédé de préparation de nouveaux dérivés de l'A-méthylbenzylamine |
| US469608A US3928603A (en) | 1970-10-28 | 1974-05-13 | New derivatives of alpha-methyl benzylamine in treating inflammation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7125902A FR2145430A1 (en) | 1971-07-15 | 1971-07-15 | 3-chloro-4-cyclohexyl-alphamethyl benzylamines - - antiinflammatory and analgesic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2145430A1 true FR2145430A1 (en) | 1973-02-23 |
| FR2145430B1 FR2145430B1 (enExample) | 1974-09-06 |
Family
ID=9080398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7125902A Granted FR2145430A1 (en) | 1970-10-28 | 1971-07-15 | 3-chloro-4-cyclohexyl-alphamethyl benzylamines - - antiinflammatory and analgesic agents |
Country Status (2)
| Country | Link |
|---|---|
| CH (1) | CH545268A (enExample) |
| FR (1) | FR2145430A1 (enExample) |
-
1971
- 1971-07-15 FR FR7125902A patent/FR2145430A1/fr active Granted
- 1971-11-16 CH CH1660871A patent/CH545268A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH545268A (fr) | 1973-12-15 |
| FR2145430B1 (enExample) | 1974-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |