FR2142803A1 - 3,4-disubstd anilides - having antiandrogenic activity - Google Patents

3,4-disubstd anilides - having antiandrogenic activity

Info

Publication number
FR2142803A1
FR2142803A1 FR7123250A FR7123250A FR2142803A1 FR 2142803 A1 FR2142803 A1 FR 2142803A1 FR 7123250 A FR7123250 A FR 7123250A FR 7123250 A FR7123250 A FR 7123250A FR 2142803 A1 FR2142803 A1 FR 2142803A1
Authority
FR
France
Prior art keywords
anilides
antiandrogenic activity
exception
tert
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7123250A
Other languages
French (fr)
Other versions
FR2142803B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Priority to FR7123250A priority Critical patent/FR2142803A1/en
Publication of FR2142803A1 publication Critical patent/FR2142803A1/en
Application granted granted Critical
Publication of FR2142803B1 publication Critical patent/FR2142803B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

anilides - having antiandrogenic activity. Novel Title cpds. of formula: (where R = cyclopropyl, cyclobutyl, loweralkyl having at least one sec. or tert. C-atom; R1 = H, lower alkyl; Y = Br, I, NO2, - COOH (opt. esterified with lower alkanol), OH, lower alkoxy, lower alkanoyl, lower alkanoyloxy, lower polyfluoroalkoxy, CF3S-, CF3-SO-, CF3-SO2-, lower polyfluoroalkyl (with the exception of CF3); X = NO2, I, CF3, Br (with the exception of case where X = Y = Br) or Y = CF3 and X = I, Br or when R = 6-8C alkyl at least two of the C atoms being sec. or tert., X may also be NO2) and their salts are used to treat prostate hypertrophy, Stein-Leventhal syndrome, idiophatic hirsutims and acne. They can be used in veterinary medicine as a means of chemical castration.
FR7123250A 1971-06-25 1971-06-25 3,4-disubstd anilides - having antiandrogenic activity Granted FR2142803A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7123250A FR2142803A1 (en) 1971-06-25 1971-06-25 3,4-disubstd anilides - having antiandrogenic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7123250A FR2142803A1 (en) 1971-06-25 1971-06-25 3,4-disubstd anilides - having antiandrogenic activity

Publications (2)

Publication Number Publication Date
FR2142803A1 true FR2142803A1 (en) 1973-02-02
FR2142803B1 FR2142803B1 (en) 1974-08-30

Family

ID=9079328

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7123250A Granted FR2142803A1 (en) 1971-06-25 1971-06-25 3,4-disubstd anilides - having antiandrogenic activity

Country Status (1)

Country Link
FR (1) FR2142803A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100172A1 (en) * 1982-07-23 1984-02-08 Imperial Chemical Industries Plc Amide derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100172A1 (en) * 1982-07-23 1984-02-08 Imperial Chemical Industries Plc Amide derivatives

Also Published As

Publication number Publication date
FR2142803B1 (en) 1974-08-30

Similar Documents

Publication Publication Date Title
GB1097544A (en) Phenoxy-substituted alkanols
SE406690B (en) USE OF CERTAIN TRIAZOLOBENZOXAZOLE OR TRIAZOLOBENSOTIAZOLE COMPOUNDS AND / OR PHYTOLOGICALLY ACCEPTABLE ACID ADDITIONAL SALTS THEREOF FOR THE CONTROL OF PLANT PATHOGENIC MUSHROOMS AND BACTERIA
ES398963A1 (en) Cephalosporin process and product
SE306139B (en)
FR2142803A1 (en) 3,4-disubstd anilides - having antiandrogenic activity
NL7108495A (en) 3,4-disubstd anilides - having antiandrogenic activity
GB1045010A (en) Process for manufacturing ª‰-hydroxyethyl ethers of rutin
ES442375A1 (en) 10*111 jihidoro 33 karubokishishipuroheputajin oyobi sono nn okisaido
FR2160704A2 (en) Esters of spirocyclohexane naphthalene acetic acid - - antiinflammatories and analgesics
GB1095765A (en) Lincomycin derivatives
GB1090359A (en) New adenosine-ketals
CH610876A5 (en) Process for the preparation of 4-chlorophenoxyisobutyrylsalicylic acid
GB1132040A (en) Complex salts of alkyl phenols and alkyl phenol sulphides
BE596629A (en) Esterification process, esters obtained by this process and compositions containing these esters.
ES352490A3 (en) A procedure to produce a steroid- (17-alpha, 16-al-fa-d) -oxazoline. (Machine-translation by Google Translate, not legally binding)
ES398378A1 (en) Procedure for the obtaining derivatives of erythromycin. (Machine-translation by Google Translate, not legally binding)
FR1433515A (en) Process for the production of very low carbon stainless steels
ES260955A1 (en) Procedure for obtaining new derivatives of glicirretinic acid (Machine-translation by Google Translate, not legally binding)
GB683954A (en) The production of oxalate coatings on metals
ES289923A1 (en) Procedure for the production of verrucarine derivatives (Machine-translation by Google Translate, not legally binding)
GB1123561A (en) Improvements in and relating to novel 9ªß,10ª‡-steroids, methods of producing the same, pharmaceutical preparations containing said 9ªß,10ª‡-steroids as active substancesand methods of producing said preparations
GB962943A (en) Improvements in or relating to the preparation of penicillins
GB910325A (en) New and improved morphine derivatives and process of making
GB1321531A (en) Compositions and methods useful in veterinary medicine
ES408019A1 (en) Preparation of n-diethylaminoethyl-2-methosy-4-amino-5-chloro benzamide

Legal Events

Date Code Title Description
CD Change of name or company name
CC Supplementary certificate of protection laid open to the public (law of 25 june 1990)

Free format text: 92C0012, 920207

CB Supplementary certificate of protection granted (law of 25 june 1990)

Free format text: 92C0012, 710625

CP Supplementary certificate of protection filed