FR2141579A1 - 1-(4-fluorophenyl)-4-piperazinyl-1-butanones - - with analgesic and neuroleptic activity - Google Patents
1-(4-fluorophenyl)-4-piperazinyl-1-butanones - - with analgesic and neuroleptic activityInfo
- Publication number
- FR2141579A1 FR2141579A1 FR7121994A FR7121994A FR2141579A1 FR 2141579 A1 FR2141579 A1 FR 2141579A1 FR 7121994 A FR7121994 A FR 7121994A FR 7121994 A FR7121994 A FR 7121994A FR 2141579 A1 FR2141579 A1 FR 2141579A1
- Authority
- FR
- France
- Prior art keywords
- fluorophenyl
- analgesic
- butanones
- piperazinyl
- substd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000701 neuroleptic effect Effects 0.000 title abstract 2
- POWKNAVDGFNMSG-UHFFFAOYSA-N 1-(4-fluorophenyl)-4-piperazin-1-ylbutan-1-one Chemical class C1=CC(F)=CC=C1C(=O)CCCN1CCNCC1 POWKNAVDGFNMSG-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 (7-9C) Chemical group 0.000 abstract 1
- FXFDJSQOCVDXBX-UHFFFAOYSA-N 2-(3-chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane Chemical compound C1=CC(F)=CC=C1C1(CCCCl)OCCO1 FXFDJSQOCVDXBX-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7121994A FR2141579A1 (en) | 1971-06-17 | 1971-06-17 | 1-(4-fluorophenyl)-4-piperazinyl-1-butanones - - with analgesic and neuroleptic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7121994A FR2141579A1 (en) | 1971-06-17 | 1971-06-17 | 1-(4-fluorophenyl)-4-piperazinyl-1-butanones - - with analgesic and neuroleptic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2141579A1 true FR2141579A1 (en) | 1973-01-26 |
| FR2141579B1 FR2141579B1 (https=) | 1974-08-30 |
Family
ID=9078814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7121994A Granted FR2141579A1 (en) | 1971-06-17 | 1971-06-17 | 1-(4-fluorophenyl)-4-piperazinyl-1-butanones - - with analgesic and neuroleptic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2141579A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011105628A (ja) * | 2009-11-16 | 2011-06-02 | Tosoh Corp | N−(2−アルコキシメチル)トリエチレンジアミン類の製造法 |
-
1971
- 1971-06-17 FR FR7121994A patent/FR2141579A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011105628A (ja) * | 2009-11-16 | 2011-06-02 | Tosoh Corp | N−(2−アルコキシメチル)トリエチレンジアミン類の製造法 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2141579B1 (https=) | 1974-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |