FR1603622A - Glucuronides of 3-indolyl-aliphatic carboxylic acids of general formula (I): R1 = H, lower alkyl, lower alkoxy, lower alkylthio or halogen; R2 and R3 = H, - Google Patents

Glucuronides of 3-indolyl-aliphatic carboxylic acids of general formula (I): R1 = H, lower alkyl, lower alkoxy, lower alkylthio or halogen; R2 and R3 = H,

Info

Publication number
FR1603622A
FR1603622A FR1603622DA FR1603622A FR 1603622 A FR1603622 A FR 1603622A FR 1603622D A FR1603622D A FR 1603622DA FR 1603622 A FR1603622 A FR 1603622A
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FR
France
Prior art keywords
glucuronides
indolyl
halogen
general formula
carboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of FR1603622A publication Critical patent/FR1603622A/en
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Glucuronides of 3-indolyl-aliphatic carboxylic acids of general formula (I): R1 = H, lower alkyl, lower alkoxy, lower alkylthio or halogen; R2 and R3 = H, phenyl or lower alkyl; R4 = pyridyl or styryl; R5, R6 and R7 = H or acetyl; R8 = H or lower alkyl; n = 0,1 or 2. (I) Have anti-inflammatory activity with hardly any side-effects and are non-toxic. They have also anti-pyretic and analgesic activity.
FR1603622D 1967-09-29 1968-09-27 Glucuronides of 3-indolyl-aliphatic carboxylic acids of general formula (I): R1 = H, lower alkyl, lower alkoxy, lower alkylthio or halogen; R2 and R3 = H, Expired FR1603622A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6292867 1967-09-29
JP6292967 1967-09-29

Publications (1)

Publication Number Publication Date
FR1603622A true FR1603622A (en) 1971-05-10

Family

ID=26403987

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1603622D Expired FR1603622A (en) 1967-09-29 1968-09-27 Glucuronides of 3-indolyl-aliphatic carboxylic acids of general formula (I): R1 = H, lower alkyl, lower alkoxy, lower alkylthio or halogen; R2 and R3 = H,

Country Status (7)

Country Link
AT (2) AT302542B (en)
BE (1) BE721522A (en)
CH (1) CH508655A (en)
DE (1) DE1795424C3 (en)
FR (1) FR1603622A (en)
GB (1) GB1187903A (en)
NL (1) NL6813867A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1427945A (en) * 1973-08-22 1976-03-10 Lepetit Spa Aminopyrrole derivatives
WO2021087096A1 (en) * 2019-11-01 2021-05-06 The Regents Of The University Of California P53 modulators and uses thereof

Also Published As

Publication number Publication date
AT302542B (en) 1972-10-25
DE1795424C3 (en) 1973-09-20
CH508655A (en) 1971-06-15
AT300203B (en) 1972-07-25
BE721522A (en) 1969-03-03
DE1795424A1 (en) 1969-10-23
DE1795424B2 (en) 1973-02-01
NL6813867A (en) 1969-04-01
GB1187903A (en) 1970-04-15

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Legal Events

Date Code Title Description
ST Notification of lapse