FR2088183A1 - Alpha-(3-pyridazon-6-yl)oxoalkanoic acids - with antiinflammatory sedative neuroleptic antihistaminic activity - Google Patents

Alpha-(3-pyridazon-6-yl)oxoalkanoic acids - with antiinflammatory sedative neuroleptic antihistaminic activity

Info

Publication number
FR2088183A1
FR2088183A1 FR7019079A FR7019079A FR2088183A1 FR 2088183 A1 FR2088183 A1 FR 2088183A1 FR 7019079 A FR7019079 A FR 7019079A FR 7019079 A FR7019079 A FR 7019079A FR 2088183 A1 FR2088183 A1 FR 2088183A1
Authority
FR
France
Prior art keywords
pyridazon
neuroleptic
sedative
alpha
antiinflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7019079A
Other languages
French (fr)
Other versions
FR2088183B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferlux SA
Original Assignee
Ferlux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferlux SA filed Critical Ferlux SA
Priority to FR7019079A priority Critical patent/FR2088183A1/en
Priority to FR7128353A priority patent/FR2147845B2/fr
Publication of FR2088183A1 publication Critical patent/FR2088183A1/en
Application granted granted Critical
Publication of FR2088183B1 publication Critical patent/FR2088183B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C07D237/16—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cpds. of formula: and their salts. The substits. are widely varied. The cpds. have neuroleptic, sedative, analgesic, anti-inflammatory, antipyretic, antihistaminic activity. They are prepd. by reaction of 6-hydroxy-3-pyridazones with alkyl alpha-haloalkanoates and hydrolysis of the resultant alkyl alpha-(3-pyridazon-6-yl)oxyalkanoates.
FR7019079A 1970-05-26 1970-05-26 Alpha-(3-pyridazon-6-yl)oxoalkanoic acids - with antiinflammatory sedative neuroleptic antihistaminic activity Granted FR2088183A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7019079A FR2088183A1 (en) 1970-05-26 1970-05-26 Alpha-(3-pyridazon-6-yl)oxoalkanoic acids - with antiinflammatory sedative neuroleptic antihistaminic activity
FR7128353A FR2147845B2 (en) 1970-05-26 1971-08-03

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7019079A FR2088183A1 (en) 1970-05-26 1970-05-26 Alpha-(3-pyridazon-6-yl)oxoalkanoic acids - with antiinflammatory sedative neuroleptic antihistaminic activity
FR7128353A FR2147845B2 (en) 1970-05-26 1971-08-03

Publications (2)

Publication Number Publication Date
FR2088183A1 true FR2088183A1 (en) 1972-01-07
FR2088183B1 FR2088183B1 (en) 1974-04-12

Family

ID=26215761

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7019079A Granted FR2088183A1 (en) 1970-05-26 1970-05-26 Alpha-(3-pyridazon-6-yl)oxoalkanoic acids - with antiinflammatory sedative neuroleptic antihistaminic activity
FR7128353A Expired FR2147845B2 (en) 1970-05-26 1971-08-03

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7128353A Expired FR2147845B2 (en) 1970-05-26 1971-08-03

Country Status (1)

Country Link
FR (2) FR2088183A1 (en)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHIMICA THERAPEUTICA VOL. II, PAGES 317-322 SEPTEMBRE-OCTOBRE 1967 *
COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES, 255 PAGES 1453-55 1962 ) *

Also Published As

Publication number Publication date
FR2147845A2 (en) 1973-03-11
FR2088183B1 (en) 1974-04-12
FR2147845B2 (en) 1974-09-06

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Legal Events

Date Code Title Description
ST Notification of lapse