FR2135294A1 - - Google Patents

Info

Publication number
FR2135294A1
FR2135294A1 FR7215929A FR7215929A FR2135294A1 FR 2135294 A1 FR2135294 A1 FR 2135294A1 FR 7215929 A FR7215929 A FR 7215929A FR 7215929 A FR7215929 A FR 7215929A FR 2135294 A1 FR2135294 A1 FR 2135294A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7215929A
Other languages
French (fr)
Other versions
FR2135294B1 (enEXAMPLES
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de
Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de
Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of FR2135294A1 publication Critical patent/FR2135294A1/fr
Application granted granted Critical
Publication of FR2135294B1 publication Critical patent/FR2135294B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7215929A 1971-05-04 1972-05-04 Expired FR2135294B1 (enEXAMPLES)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712121950 DE2121950A1 (en) 1971-05-04 1971-05-04 Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de) 1971-07-26 1971-07-26 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de) 1972-03-29 1972-03-29 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (2)

Publication Number Publication Date
FR2135294A1 true FR2135294A1 (enEXAMPLES) 1972-12-15
FR2135294B1 FR2135294B1 (enEXAMPLES) 1975-10-17

Family

ID=27183398

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7215929A Expired FR2135294B1 (enEXAMPLES) 1971-05-04 1972-05-04

Country Status (15)

Country Link
US (1) US3888851A (enEXAMPLES)
AT (1) AT318619B (enEXAMPLES)
AU (1) AU4181572A (enEXAMPLES)
BE (1) BE783044A (enEXAMPLES)
BG (1) BG20593A3 (enEXAMPLES)
DD (1) DD97656A5 (enEXAMPLES)
DK (1) DK129844B (enEXAMPLES)
ES (1) ES402302A1 (enEXAMPLES)
FR (1) FR2135294B1 (enEXAMPLES)
GB (1) GB1393161A (enEXAMPLES)
HU (1) HU163960B (enEXAMPLES)
IL (1) IL39341A (enEXAMPLES)
NL (1) NL7206041A (enEXAMPLES)
PL (1) PL82381B1 (enEXAMPLES)
RO (1) RO62428A (enEXAMPLES)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017021A1 (en) * 1992-02-19 1993-09-02 Pfizer, Inc. Heterocyclic compounds for enhancing antitumor activity

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
ES2221213T3 (es) 1997-10-20 2004-12-16 F. Hoffmann-La Roche Ag Inhibidores de kinasa biciclicos.
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
MX2007012313A (es) * 2006-04-19 2007-11-21 Boehringer Ingelheim Int Dihidrotienopirimidinas para el tratamiento de enfermedades inflamatorias.
CL2007001165A1 (es) 2006-04-26 2008-01-25 Hoffmann La Roche 2-(1h-indazol-4-il)-6-(4-metanosulfonil-piperazin-1-ilmetil)-4-morfolin-4-il-tieno[3,2-d]pirimidina; procedimiento de preparacion; composicion farmaceutica; proceso de preparacion de dicha composicion; kit farmaceutico; y uso para tratar enfermedades tales como cancer, desordenes inmunes y enfermedades cardiovasculares.
MX2008013583A (es) 2006-04-26 2008-10-31 Genentech Inc Compuestos del inhibidor de fosfoinositido 3-cinasa y composiciones farmaceuticas que los contienen.
ES2377358T3 (es) 2006-04-26 2012-03-26 F. Hoffmann-La Roche Ag Compuestos farmacéuticos
BRPI0717923A2 (pt) 2006-12-07 2013-10-22 Genentech In '' composto, composição farmacêutica, método para tratar um câncer, processo para a produção de uma composição farmacêutica, usos, métodos para inibir ou modular a atividade da lipídeo quinase e kit ' '
TW200829594A (en) * 2006-12-07 2008-07-16 Piramed Ltd Phosphoinositide 3-kinase inhibitor compounds and methods of use
JP5736171B2 (ja) 2007-09-24 2015-06-17 ジェネンテック, インコーポレイテッド チアゾロピリミジンpi3k阻害剤化合物および使用方法
WO2009050242A2 (de) * 2007-10-19 2009-04-23 Boehringer Ingelheim International Gmbh Heterocyclus-substituierte piperazino-dihydrothienopyrimidine
US8354528B2 (en) 2007-10-25 2013-01-15 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
AU2010224125B2 (en) 2009-03-12 2015-05-14 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
CA2772371A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
US8173650B2 (en) 2009-05-27 2012-05-08 Genentech, Inc. Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
MX2012011887A (es) 2010-04-16 2012-11-30 Genentech Inc Foxo 3a como biomarcador predictivo para la eficacia del inhibidor de la via de quinasa pi3k/akt.
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
WO2014130923A2 (en) 2013-02-25 2014-08-28 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant
GB201410816D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) * 1964-09-29 1965-10-05 Ciba Geigy Corp Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017021A1 (en) * 1992-02-19 1993-09-02 Pfizer, Inc. Heterocyclic compounds for enhancing antitumor activity

Also Published As

Publication number Publication date
US3888851A (en) 1975-06-10
DD97656A5 (enEXAMPLES) 1973-05-12
IL39341A (en) 1975-08-31
DK129844B (da) 1974-11-25
NL7206041A (enEXAMPLES) 1972-11-07
DK129844C (enEXAMPLES) 1975-05-12
HU163960B (enEXAMPLES) 1973-11-28
PL82381B1 (enEXAMPLES) 1975-10-31
BG20593A3 (bg) 1975-12-05
FR2135294B1 (enEXAMPLES) 1975-10-17
ES402302A1 (es) 1975-04-01
IL39341A0 (en) 1972-07-26
GB1393161A (en) 1975-05-07
AT318619B (de) 1974-11-11
AU4181572A (en) 1973-11-08
RO62428A (fr) 1978-01-15
BE783044A (fr) 1972-11-06

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Legal Events

Date Code Title Description
ST Notification of lapse