FR2133508A1 - 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity - Google Patents
4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activityInfo
- Publication number
- FR2133508A1 FR2133508A1 FR7113335A FR7113335A FR2133508A1 FR 2133508 A1 FR2133508 A1 FR 2133508A1 FR 7113335 A FR7113335 A FR 7113335A FR 7113335 A FR7113335 A FR 7113335A FR 2133508 A1 FR2133508 A1 FR 2133508A1
- Authority
- FR
- France
- Prior art keywords
- acid
- prepd
- pref
- thiazolidinecarboxylic acid
- thiazolidinecarboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000694 effects Effects 0.000 title abstract 2
- 229950001139 timonacic Drugs 0.000 title abstract 2
- 238000001727 in vivo Methods 0.000 title 1
- 125000003396 thiol group Chemical class [H]S* 0.000 title 1
- DZLNHFMRPBPULJ-UHFFFAOYSA-N thioproline Chemical compound OC(=O)C1CSCN1 DZLNHFMRPBPULJ-UHFFFAOYSA-N 0.000 title 1
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical class CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 abstract 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 2
- 239000011782 vitamin Substances 0.000 abstract 2
- 229940088594 vitamin Drugs 0.000 abstract 2
- 229930003231 vitamin Natural products 0.000 abstract 2
- 235000013343 vitamin Nutrition 0.000 abstract 2
- KHBBQMHTRDEPCR-UHFFFAOYSA-N 2-(3-formylphenoxy)acetic acid Chemical compound OC(=O)COC1=CC=CC(C=O)=C1 KHBBQMHTRDEPCR-UHFFFAOYSA-N 0.000 abstract 1
- FAUAZXVRLVIARB-UHFFFAOYSA-N 4-[[4-[bis(oxiran-2-ylmethyl)amino]phenyl]methyl]-n,n-bis(oxiran-2-ylmethyl)aniline Chemical compound C1OC1CN(C=1C=CC(CC=2C=CC(=CC=2)N(CC2OC2)CC2OC2)=CC=1)CC1CO1 FAUAZXVRLVIARB-UHFFFAOYSA-N 0.000 abstract 1
- YCPXWRQRBFJBPZ-UHFFFAOYSA-N 5-sulfosalicylic acid Chemical class OC(=O)C1=CC(S(O)(=O)=O)=CC=C1O YCPXWRQRBFJBPZ-UHFFFAOYSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 229910004373 HOAc Inorganic materials 0.000 abstract 1
- 235000013878 L-cysteine Nutrition 0.000 abstract 1
- 239000004201 L-cysteine Substances 0.000 abstract 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 abstract 1
- 230000000397 acetylating effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000032823 cell division Effects 0.000 abstract 1
- 239000005515 coenzyme Substances 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
- 229960000304 folic acid Drugs 0.000 abstract 1
- 235000019152 folic acid Nutrition 0.000 abstract 1
- 239000011724 folic acid Substances 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7113335A FR2133508A1 (en) | 1971-04-15 | 1971-04-15 | 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7113335A FR2133508A1 (en) | 1971-04-15 | 1971-04-15 | 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2133508A1 true FR2133508A1 (en) | 1972-12-01 |
| FR2133508B1 FR2133508B1 (OSRAM) | 1974-09-27 |
Family
ID=9075327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7113335A Granted FR2133508A1 (en) | 1971-04-15 | 1971-04-15 | 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2133508A1 (OSRAM) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998019555A1 (en) * | 1996-11-07 | 1998-05-14 | Milo Olomouc, A.S. | Fat with specific antisclerosis effects |
| DE19711052A1 (de) * | 1997-03-03 | 1998-09-17 | Hans Prof Dr Rommelspacher | Verwendung von 2-Methyl-thiazolidin-2,4-dicarbonsäure als Mukolytikum |
| WO2005105062A3 (de) * | 2004-05-03 | 2006-02-23 | Rudy Susilo | Kombinationspräparate enthaltend 2-methylthiazolidin-2,4-dicarbonsäure |
-
1971
- 1971-04-15 FR FR7113335A patent/FR2133508A1/fr active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998019555A1 (en) * | 1996-11-07 | 1998-05-14 | Milo Olomouc, A.S. | Fat with specific antisclerosis effects |
| DE19711052A1 (de) * | 1997-03-03 | 1998-09-17 | Hans Prof Dr Rommelspacher | Verwendung von 2-Methyl-thiazolidin-2,4-dicarbonsäure als Mukolytikum |
| DE19711052C2 (de) * | 1997-03-03 | 1999-09-23 | Hans Rommelspacher | Verwendung von 2-Methyl-thiazolidin-2,4-dicarbonsäure als Mukolytikum |
| WO2005105062A3 (de) * | 2004-05-03 | 2006-02-23 | Rudy Susilo | Kombinationspräparate enthaltend 2-methylthiazolidin-2,4-dicarbonsäure |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2133508B1 (OSRAM) | 1974-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |