FR2106566A1 - Tabletting active materials - by compressing encapsulated particles - Google Patents

Tabletting active materials - by compressing encapsulated particles

Info

Publication number
FR2106566A1
FR2106566A1 FR7133428A FR7133428A FR2106566A1 FR 2106566 A1 FR2106566 A1 FR 2106566A1 FR 7133428 A FR7133428 A FR 7133428A FR 7133428 A FR7133428 A FR 7133428A FR 2106566 A1 FR2106566 A1 FR 2106566A1
Authority
FR
France
Prior art keywords
tabletting
compressing
active materials
encapsulated particles
encapsulated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7133428A
Other languages
English (en)
French (fr)
Other versions
FR2106566B1 (enrdf_load_stackoverflow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck et Cie
Merck and Co Inc
Original Assignee
Merck et Cie
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck et Cie, Merck and Co Inc filed Critical Merck et Cie
Publication of FR2106566A1 publication Critical patent/FR2106566A1/fr
Application granted granted Critical
Publication of FR2106566B1 publication Critical patent/FR2106566B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
FR7133428A 1970-09-16 1971-09-16 Tabletting active materials - by compressing encapsulated particles Granted FR2106566A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7285670A 1970-09-16 1970-09-16

Publications (2)

Publication Number Publication Date
FR2106566A1 true FR2106566A1 (en) 1972-05-05
FR2106566B1 FR2106566B1 (enrdf_load_stackoverflow) 1975-04-18

Family

ID=22110165

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7133428A Granted FR2106566A1 (en) 1970-09-16 1971-09-16 Tabletting active materials - by compressing encapsulated particles

Country Status (4)

Country Link
AU (1) AU3317871A (enrdf_load_stackoverflow)
DE (1) DE2146174A1 (enrdf_load_stackoverflow)
FR (1) FR2106566A1 (enrdf_load_stackoverflow)
NL (1) NL7112083A (enrdf_load_stackoverflow)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2185390A1 (enrdf_load_stackoverflow) * 1972-05-19 1974-01-04 Beecham Group Ltd
FR2200006A1 (enrdf_load_stackoverflow) * 1972-09-25 1974-04-19 Warner Lambert Co
DE2509572A1 (de) * 1974-03-08 1975-09-11 Beecham Group Ltd Trockenpraeparat und feine partikel
US3907983A (en) * 1973-02-16 1975-09-23 Hoffmann La Roche Pharmaceutical preparations
FR2385388A1 (enrdf_load_stackoverflow) * 1977-04-01 1978-10-27 Hoechst Ag

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173626A (en) 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
GB2075458B (en) * 1980-04-21 1983-06-02 Nicholas Pty Ltd Encapsulation of indomethacin
DE4119306C2 (de) * 1991-06-12 1996-05-30 Wheli Inter Ag Organische Rohstoffe, Zwischen- und Endprodukte für die Ernährung und zur Verwendung für technische Zwecke, die Vitalstoffe enthalten
IE940292A1 (en) * 1994-04-06 1995-10-18 Elan Corp Plc Biodegradable microcapsules and method for their manufacture

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3488418A (en) * 1965-11-18 1970-01-06 Sterling Drug Inc Sustained relief analgesic composition
US3524910A (en) * 1965-11-18 1970-08-18 Sterling Drug Inc Sustained relief analgesic compositions
US3557279A (en) * 1969-06-12 1971-01-19 Merck & Co Inc Microencapsulation form of an anti-inflammatory drug

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3488418A (en) * 1965-11-18 1970-01-06 Sterling Drug Inc Sustained relief analgesic composition
US3524910A (en) * 1965-11-18 1970-08-18 Sterling Drug Inc Sustained relief analgesic compositions
US3557279A (en) * 1969-06-12 1971-01-19 Merck & Co Inc Microencapsulation form of an anti-inflammatory drug

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2185390A1 (enrdf_load_stackoverflow) * 1972-05-19 1974-01-04 Beecham Group Ltd
FR2200006A1 (enrdf_load_stackoverflow) * 1972-09-25 1974-04-19 Warner Lambert Co
US3907983A (en) * 1973-02-16 1975-09-23 Hoffmann La Roche Pharmaceutical preparations
DE2509572A1 (de) * 1974-03-08 1975-09-11 Beecham Group Ltd Trockenpraeparat und feine partikel
FR2385388A1 (enrdf_load_stackoverflow) * 1977-04-01 1978-10-27 Hoechst Ag

Also Published As

Publication number Publication date
DE2146174A1 (de) 1972-03-30
FR2106566B1 (enrdf_load_stackoverflow) 1975-04-18
AU3317871A (en) 1973-03-15
NL7112083A (enrdf_load_stackoverflow) 1972-03-20

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Legal Events

Date Code Title Description
ST Notification of lapse