FR2092095A1 - Silymarin isolation - Google Patents
Silymarin isolationInfo
- Publication number
- FR2092095A1 FR2092095A1 FR7114669A FR7114669A FR2092095A1 FR 2092095 A1 FR2092095 A1 FR 2092095A1 FR 7114669 A FR7114669 A FR 7114669A FR 7114669 A FR7114669 A FR 7114669A FR 2092095 A1 FR2092095 A1 FR 2092095A1
- Authority
- FR
- France
- Prior art keywords
- silymarin
- isolation
- esp
- fat
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SEBFKMXJBCUCAI-UHFFFAOYSA-N NSC 227190 Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC=C(C=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002955 isolation Methods 0.000 title abstract 2
- SEBFKMXJBCUCAI-HKTJVKLFSA-N silibinin Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 title abstract 2
- 229960004245 silymarin Drugs 0.000 title abstract 2
- 235000017700 silymarin Nutrition 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 235000019439 ethyl acetate Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- -1 fatty acid ester Chemical class 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/40—Separation, e.g. from natural material; Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702020407 DE2020407A1 (de) | 1970-04-27 | 1970-04-27 | Technisches Verfahren zur Isolierung von Silimarin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2092095A1 true FR2092095A1 (en) | 1972-01-21 |
| FR2092095B1 FR2092095B1 (enExample) | 1974-09-27 |
Family
ID=5769446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7114669A Granted FR2092095A1 (en) | 1970-04-27 | 1971-04-23 | Silymarin isolation |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE766228A (enExample) |
| DE (1) | DE2020407A1 (enExample) |
| FR (1) | FR2092095A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008039271A1 (de) | 2007-12-23 | 2009-06-25 | Euromed Sa | Neuer Mariendistelextrakt, Verfahren zur Herstellung und Verwendung |
| EP2959910A1 (de) | 2014-06-26 | 2015-12-30 | Bionorica Se | Mariendistelextrakt aus Mariendistelfrüchteschalen, Verfahren zur Herstellung und Verwendung |
| EP4696313A1 (en) | 2024-08-13 | 2026-02-18 | WÖRWAG Pharma GmbH & Co.KG | Formulation of krill oil and silymarin |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2010026A1 (enExample) * | 1968-06-01 | 1970-02-13 | Madaus & Co Dr |
-
1970
- 1970-04-27 DE DE19702020407 patent/DE2020407A1/de active Pending
-
1971
- 1971-04-23 BE BE766228A patent/BE766228A/xx unknown
- 1971-04-23 FR FR7114669A patent/FR2092095A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2010026A1 (enExample) * | 1968-06-01 | 1970-02-13 | Madaus & Co Dr |
Also Published As
| Publication number | Publication date |
|---|---|
| BE766228A (fr) | 1971-10-25 |
| DE2020407A1 (de) | 1971-11-11 |
| FR2092095B1 (enExample) | 1974-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CA | Change of address | ||
| ST | Notification of lapse |