FR2088145A1 - 6-hydroxy nicotinic acid derivs - with local anaesthetic activity - Google Patents
6-hydroxy nicotinic acid derivs - with local anaesthetic activityInfo
- Publication number
- FR2088145A1 FR2088145A1 FR7018769A FR7018769A FR2088145A1 FR 2088145 A1 FR2088145 A1 FR 2088145A1 FR 7018769 A FR7018769 A FR 7018769A FR 7018769 A FR7018769 A FR 7018769A FR 2088145 A1 FR2088145 A1 FR 2088145A1
- Authority
- FR
- France
- Prior art keywords
- nicotinic acid
- local anaesthetic
- acid derivs
- anaesthetic activity
- hydroxy nicotinic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BLHCMGRVFXRYRN-UHFFFAOYSA-N 6-hydroxynicotinic acid Chemical compound OC(=O)C1=CC=C(O)N=C1 BLHCMGRVFXRYRN-UHFFFAOYSA-N 0.000 title 1
- 230000003444 anaesthetic effect Effects 0.000 title 1
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 2
- DZPVCIBOAAIOBA-UHFFFAOYSA-N 6-[2-(diethylamino)ethoxy]pyridine-3-carboxylic acid Chemical compound CCN(CC)CCOC1=CC=C(C(O)=O)C=N1 DZPVCIBOAAIOBA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229960003920 cocaine Drugs 0.000 abstract 1
- 125000006264 diethylaminomethyl group Chemical group [H]C([H])([H])C([H])([H])N(C([H])([H])*)C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- DQKXQSGTHWVTAD-UHFFFAOYSA-N pramocaine Chemical compound C1=CC(OCCCC)=CC=C1OCCCN1CCOCC1 DQKXQSGTHWVTAD-UHFFFAOYSA-N 0.000 abstract 1
- 229960001896 pramocaine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7018769A FR2088145A1 (en) | 1970-05-22 | 1970-05-22 | 6-hydroxy nicotinic acid derivs - with local anaesthetic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7018769A FR2088145A1 (en) | 1970-05-22 | 1970-05-22 | 6-hydroxy nicotinic acid derivs - with local anaesthetic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2088145A1 true FR2088145A1 (en) | 1972-01-07 |
| FR2088145B1 FR2088145B1 (cg-RX-API-DMAC10.html) | 1973-04-06 |
Family
ID=9055966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7018769A Granted FR2088145A1 (en) | 1970-05-22 | 1970-05-22 | 6-hydroxy nicotinic acid derivs - with local anaesthetic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2088145A1 (cg-RX-API-DMAC10.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0405931A3 (en) * | 1989-06-30 | 1991-09-25 | Eli Lilly And Company | Improvements in and relating to anticonvulsant agents |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE743467C (de) * | 1938-02-28 | 1944-01-14 | Boehringer & Soehne Gmbh | Verfahren zur Herstellung von Nicotinsaeure-alkaminestern |
-
1970
- 1970-05-22 FR FR7018769A patent/FR2088145A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE743467C (de) * | 1938-02-28 | 1944-01-14 | Boehringer & Soehne Gmbh | Verfahren zur Herstellung von Nicotinsaeure-alkaminestern |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0405931A3 (en) * | 1989-06-30 | 1991-09-25 | Eli Lilly And Company | Improvements in and relating to anticonvulsant agents |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2088145B1 (cg-RX-API-DMAC10.html) | 1973-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |